A5013676522- Colorectal Cancer Treatments and Studies
- Inflammatory Biomarkers in Disease Prognosis
- Sarcoma Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Lipids, and Metabolism
- HER2/EGFR in Cancer Research
- Peptidase Inhibition and Analysis
- MicroRNA in disease regulation
- Colorectal and Anal Carcinomas
- Lung Cancer Treatments and Mutations
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Regulation of Appetite and Obesity
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Prostate Cancer Treatment and Research
- Childhood Cancer Survivors' Quality of Life
- Management of metastatic bone disease
- Colorectal Cancer Surgical Treatments
- Genetic factors in colorectal cancer
- PI3K/AKT/mTOR signaling in cancer
- Hormonal Regulation and Hypertension
- Vascular Tumors and Angiosarcomas
- Cancer survivorship and care
- Brain Metastases and Treatment
Pamukkale University
2014-2025
Denizli Devlet Hastanesi
2013-2018
Cancer cachexia is one of the most frequent effects malignancy, often associated with poor prognosis, and may account for up to 20% cancer deaths. The aim our study was evaluate relationship serum levels resistin leptin in patients advanced non-small cell lung cancer.A total 67 chemotherapy-naïve advanced-stage a control group containing 20 healthy individuals without known chronic disease were enrolled this study. All age sex matched. Demographic, anthropometric, laboratory data adipokines...
Abstract Epithelial ovarian cancer (EOC) is the second leading cause of death among women with gynecological cancers, particularly in high-income countries. Despite significant advancements molecular oncology and an initially positive response to primary chemotherapy, development drug resistance remains a major challenge effective management EOC. Consequently, there urgent need for innovative biological markers that can enable early diagnosis provide more accurate predictions recurrence risk...
Primary mesenchymal tumors of the colon are extremely rare among soft tissue sarcomas. These more aggressive and have poorer prognosis than adenocarcinoma colon. Here, we presented 3 cases primary Their histopathological diagnoses leiomyosarcoma, pleomorphic liposarcoma, desmoplastic small round cell tumor, respectively. The rarity makes it difficult to approach treatment predict these tumors.
Advanced bladder cancer (BC) is associated with an inflammatory nature and poor prognosis Inflammatory biomarkers are potential predictors in BC. We conducted a study to assess the prognostic value of pretreatment neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR) advanced cancer.A total 226-patients muscle-invasive BC (MIBC) were included. Overall (OS) progression-free survival estimated using Kaplan-Meier method log-rank test was used for...
Objective This study aimed to evaluate the efficacy and safety profile of capecitabine oxaliplatin (CAPOX) 5-fluorouracil, leucovorin, (FOLFOX) regimens as adjuvant treatment in patients with stage III colon cancer. Methods A total 243 who received CAPOX FOLFOX chemotherapy between 2014 2018 for cancer two centers were retrospectively studied. Among patients, 106 (43.6%) 137 (56.4%) treated using regimens, respectively. Efficacy, treatment-related side effects, overall survival rates these...
Ovarian cancer is a heterogeneous disease, where chronic inflammation plays key role in carcinogenesis. In this study, it aimed to analyze the relationship with prognosis and chemotherapy response clinicopathologicalnvariables epithelial ovarian cancers such as proliferation of PD-1 +, CD8 CD4 CD3 + T-lymphocytes infiltrating tumor stroma.Seventy-six cases diagnosed primary from biopsy or surgical resection materials were included study. Immunreactivity CD3, CD4, CD8, PD1 was evaluated...
The aim of this study is to evaluate the efficacy and toxicity trastuzumab emtansine (T-DM1) in cases with metastatic breast cancer (mBC) different lines treatment.Retrospective analysis T-DM1 results human epidermal growth factor receptor 2 (Her2) positive 414 mBC from 31 centers Turkey.Except 2, all were female a median age 47. had been used as second-line therapy 37.7% number cycles was 9. Progression-free survival (PFS) overall (OS) times according line treatment. OS found 43, 41, 46, 23...
The prognosis of patients with advanced HCC can vary widely depending on factors such as the stage cancer, patient's overall health, and treatment regimens. This study aimed to investigate survival outcomes associated in hepatocellular carcinoma (HCC). In this retrospective study, data from 23 medical oncology clinics were analyzed. Progression-free (PFS) (OS) values estimated using Kaplan–Meier method. Prognostic which identified univariate analysis subsequently evaluated a multivariate...
Fibromuscular dysplasia (FMD) is an uncommon disorder, accounting for less than 10% of cases renal artery stenosis, and typically presenting with hypertension in young women. This article reportsthe case a previously healthy 37-year-old man acute-onset, severe, bilateral flank pain. Initially treated ureteral colic urinary tract infection, he was transferred to the nephrology clinic upon recognition rising serum creatinine. He found have FMD arteries stenotic pattern on right side dissecting...
Objective Fear of cancer recurrence (FCR) is an important psychological trauma associated with reduction in the quality life, disruptions level adjustment, emotional distress and anxiety. The purpose study was to evaluate impact patient–physician relationship on FCR. Methods designed as a multicentre survey study. survivors, who were under remission, evaluated structured questionnaires. Patient–physician (PPR) scale which higher scores indicate better FCR inventory used. Results Between...
Taxane-containing combinations are recommended for the first-line therapy of advanced gastric cancer. It is not known which chemotherapy regimen best with trastuzumab HER2-positive patients. The aim this study was to compare taxane-containing intensified versus standard in combination treatment adenocarcinoma.This a retrospective multicenter Turkish Oncology Group. A total 130 patients inoperable locally advanced, recurrent, or metastatic adenocarcinoma being given plus as were included from...
Introduction: Quality of life (QoL) issues are importance in relatives women with breast cancer (BC)as caregivers neglecting their own needs due to care a patient and also as regarding the potential risk themselves developing BC. The objectives present study were compare QoL female treatment for cancer. To date, no had examined multi-dimensional accompanying people compared them into two groups whose first degree second degree. Methods: was assessed using Life-Family Version (QOL-FV) scale....
Background: Merkel cell carcinoma (MCC) is a rare but highly aggressive neuroendocrine of the skin. In this study, we aimed to evaluate clinicopathologic characteristics, treatment outcomes, and survival MCC cases in Turkey. Materials Methods: The patients diagnosed with between 1999 2018 at twenty different centers Turkey were included study. Patient tumor characteristics adjuvant metastatis outcomes analyzed retrospectively. Results: median age totally 89 was 70 (26–93). most common...
Aims: Acute myeloid leukemia (AML) is the most common type of in adults. Lung cancer one types cancer. The concomitant presentation AML and lung extremely rare. This study aimed to report a case series acute as metachronous or synchronous. Methods: We describe 6 cases with diagnosis these two diseases between years 2016-2020 our hospital. Patients treated hospital were retrospectively reviewed. Clinical characteristics, immunohistochemical genetic findings, treatments outcomes collected....
Purpose: Studies conducted to date showed that circulating tumor DNA (ctDNA)-based next generation sequencing (NGS) panels are beneficial in the treatment strategies of patients with metastatic colorectal cancer (mCRC). In this study; we planned determine frequencies various genetic alterations mCRC by ctDNA-based NGS analyses, evaluate concordance rates comparing these results standard polymerase chain reaction (PCR) and investigate effect detected on overall survival progression-free...
Objective:We analysed the relationship between albumin and CRP related inflammation markers (Controlling nutritional status(Conut)score, lymphocyte factor(LA), albumin-bilirubin score (ALBI), highly sensitive modified Glasgow prognostic (Hs-mGPS), score(GPS)) locoregional treatment response in HCC. Materials methods:Among 180 HCC patients, 63 patients who underwent therapy were included this study. Albumin immuno-nutrition scores calculated by recording routine laboratory tests fourth eighth...