- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Palliative Care and End-of-Life Issues
- Acute Kidney Injury Research
- Health Systems, Economic Evaluations, Quality of Life
- Organ Donation and Transplantation
- Chronic Kidney Disease and Diabetes
- Healthcare Policy and Management
- Patient-Provider Communication in Healthcare
- Diversity and Career in Medicine
- Renal Diseases and Glomerulopathies
- Intensive Care Unit Cognitive Disorders
- Vascular Procedures and Complications
- Patient Satisfaction in Healthcare
- Renal Transplantation Outcomes and Treatments
- Innovations in Medical Education
- Muscle and Compartmental Disorders
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Pharmacological Effects and Toxicity Studies
- Childhood Cancer Survivors' Quality of Life
- Epilepsy research and treatment
- Antimicrobial Resistance in Staphylococcus
- Blood Pressure and Hypertension Studies
University Hospitals Birmingham NHS Foundation Trust
2018-2025
Heartlands Hospital
2015-2025
NIHR Surgical Reconstruction and Microbiology Research Centre
2020-2024
University of Manchester
2024
National Heart Foundation Hospital & Research Institute
2024
West Midlands Deanery
2023
National Kidney Foundation
2023
Wayne State University
2023
Creative Commons
2023
Heart of England NHS Foundation Trust
2011-2019
BackgroundIndividuals with rare kidney diseases account for 5–10% of people chronic disease, but constitute more than 25% patients receiving replacement therapy. The National Registry Rare Kidney Diseases (RaDaR) gathers longitudinal data from these conditions, which we used to study disease progression and outcomes death failure.MethodsPeople aged 0–96 years living 28 types were recruited 108 UK renal care facilities. primary cumulative incidence mortality failure in individuals diseases,...
Background. There is little information on factors influencing patient choice of renal replacement modality (RRM) in the UK. Pre-dialysis education programmes have been associated with increased uptake peritoneal dialysis (PD) other countries but their relevance informing within UK centres has not extensively studied. In this study, we examined how different treatment modalities [haemodialysis (HD), PD and conservative management (CM)] influenced by personal demographic parameters.
Acute renal failure (ARF) is a diverse condition with no standardized definition and managed in several sub-specialty areas within hospitals. Its incidence aetiology are unknown studies show wide range of incidences. ARF becoming more common as the population ages leading to hypothesis that much higher than previous estimates.This prospective study investigated incidence, outcomes based on classification treated by replacement therapy (RRT) all hospitals where such treatment takes place....
There have been few studies of earlier systematic intervention to reduce the impact acute kidney injury (AKI). In 2009, we piloted an AKI outreach service with a before and after study, report on study its longer-term follow-up.AKI patients were identified using laboratory delta check for creatinine 75%. 4-week phase received standard care. consecutive 7-week team nephrology doctors nurses reviewed all alerts twice daily, 5 days week. The primary clinical caring patient was called be given...
Severe acute kidney injury (AKI) occurs in 2-7% of all hospital admissions and is an independent poor prognostic marker. Nevertheless, information on the long-term outcome AKI factors influencing this limited.To describe short- patients requiring renal replacement therapy (RRT) for severe to examine affecting patient survival recovery.Single centre retrospective analysis 481 consecutive over a period 39 months.12 months.overall mortality RRT dependency at 30 days, 90 days 1 year.Survival...
As a result of difficulties related to their illness, diagnosis and treatment, patients with end-stage renal disease experience significant emotional psychological problems, which untreated can have considerable negative impact on health wellbeing. Despite evidence that desire improved support, management psychosocial particularly at the lower-level, remains sub-optimal. There is limited understanding specific support need want, from whom, when, also lack data what helps hinders staff in...
Lower-level emotional and psychological difficulties ('distress') in patients with end stage renal disease (ESRD), can lead to reduced quality of life poor clinical outcomes. National guidelines mandate provision support for yet little is known about the that may require, or challenges staff experience identifying responding patient distress.Mixed methods study units at four NHS Trusts West Midlands, UK involving cross-sectional surveys ESRD unit semi-structured interviews 46...
Objectives To explore patient perceptions and experiences of mild-to-moderate emotional distress the support offered by kidney units to patients with end-stage disease. Methods In-depth, semi-structured qualitative interviews (n = 46) being treated for disease in four hospital Trusts, data analysed thematically. Results Patients described multiple sources talked about substantial burden that challenges raised their ability manage condition develop coping strategies. Many did not feel it...
This paper discusses the features of an effective long-term haemodialysis catheter and identifies some complications that improved dialysis design can overcome. It benefits using Glidepath TM Long Term Haemodialysis Catheter illustrates these with case studies feedback from patients
Background: Patients with chronic kidney disease (CKD) face an elevated risk of cardiovascular (CVD), particularly those estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m². Aims: To assess low-density lipoprotein cholesterol (LDL-C) values and the proportion pre-dialysis patients achieving national international targets. Methods: This was a retrospective audit (May–October 2024) 272 aged >18 years attending clinic (estimated m2) at Renal Unit, Birmingham Heartlands...
Cognitive impairment (CI) is very common condition that occurs in haemodialysis patients and it associated with reduced functional capacity mortality. We assessed the change cognitive function during risk factors.All ≥50 years, on for ≥3 months, no dementia from 2 dialysis centres were selected. Cognition was before after a session using parallel versions of Montreal Assessment (MOCA) tool. Multiple regression used to examine potential confounders.Eight-two completed both tests - median age...
Some Indoasian (IA) patients with established renal failure travel abroad for commercial kidney transplantation. We compared the 1-year outcomes of IA from one UK region who received overseas transplants receiving local living donor (LD) transplantation, deceased (DD) and dialysis.Between 1996 2006, 40 adults were transplanted overseas; 38 IA, follow-up data available on 36 patients. Forty LD transplants, 156 DD locally. A cohort 120 prospective dialysis was also used as a comparator...
Objectives To explore staff perceptions of barriers to the identification mild moderate distress and provision emotional support in patients with end-stage renal disease. Methods Qualitative semi-structured interviews two hospitals (n = 31), data analysed using a hybrid approach combining thematic analysis aspects grounded theory. Results Staff appeared very aware that many disease experience distress, most thought distressed should be helped as part routine care. However, practice was...
Objectives To assess the prevalence of mild-to-moderate distress in patients with end-stage renal disease (ESRD) and determine association between patient characteristics. Design Cross-sectional survey using emotion thermometer problem list. Setting Renal units four hospital Trusts West Midlands, UK. Participants Adult stage 5 chronic kidney who were: (1) On prerenal replacement therapy. (2) dialysis for less than 2 years. (3) years or more (4) With a functioning transplant. Outcomes The...