A5101645222- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Spine and Intervertebral Disc Pathology
- Cancer-related molecular mechanisms research
- Spinal Fractures and Fixation Techniques
- Hepatocellular Carcinoma Treatment and Prognosis
- Management of metastatic bone disease
- RNA modifications and cancer
- Medical Imaging and Analysis
- MicroRNA in disease regulation
- Liver Disease and Transplantation
- MRI in cancer diagnosis
- Liver Disease Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Cancer, Hypoxia, and Metabolism
- Traditional Chinese Medicine Studies
- Advanced X-ray and CT Imaging
- Acute Myocardial Infarction Research
- Gastric Cancer Management and Outcomes
- Eating Disorders and Behaviors
- Sepsis Diagnosis and Treatment
- Attention Deficit Hyperactivity Disorder
- Nanoparticle-Based Drug Delivery
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Organ Transplantation Techniques and Outcomes
Beijing University of Chinese Medicine
2025
Chinese PLA General Hospital
2025
Osaka University
2021-2024
Osaka Health Science University
2021-2024
Sichuan University
2024
West China Hospital of Sichuan University
2024
Capital Medical University
2019-2022
Beijing Children’s Hospital
2019-2022
Central South University
2017-2022
Second Xiangya Hospital of Central South University
2022
The extracellular signals which regulate the myogenic program are transduced to nucleus by mitogen-activated protein kinases (MAPKs). We have investigated role of two MAPKs, p38 and signal-regulated kinase (ERK), whose activities undergo significant changes during muscle differentiation. is rapidly activated in myocytes induced differentiate. This activation differs from those triggered stress cytokines, because it not linked Jun–N-terminal stimulation maintained whole process myotube...
Early identification of risk factors associated with early neurological deterioration (END) in patients acute minor stroke and large vessel occlusion (LVO) receiving intravenous thrombolysis (IVT) could assist formulating treatment decisions. Consecutive LVO were extracted from a single-center prospective database spanning January 2020 to December 2023. END was defined as an increase ≥ 4 points the National Institutes Health Stroke Scale (NIHSS) score baseline, or 2 any single NIHSS item,...
Background: Most previous studies have found that human intestinal microbiota affect the symptoms of autism spectrum disorder (ASD), especially gastrointestinal (GI) symptoms, but regarding this, there is limited data non-western ethnicity. Probiotics can reconstitute host and strengthen function, however, clinical proving effect probiotics treatment on ASD lacking. Methods: This study explored significant differences between neurotypical (NT), improvement applied behavior analysis (ABA)...
The serum creatinine/cystatin C ratio (CCR) or sarcopenia index is considered a useful marker of muscle mass. However, its usefulness in late-stage older adults remains unclear. We aimed to determine the CCR as an indicator community-dwelling Japanese aged >75 years.
Premonitory urges (PUs) are sensory phenomena that immediately precede tics. The Urge for Tics Scale (PUTS) is widely used to assess the severity of PUs, but psychometric properties PUTS and clinical features PU in Chinese patients with tic disorders still unclear. In this study, we examined version a large sample (including 367 pediatric disorders). We found no difference different age groups. exploratory factor analysis (EFA) showed emergence four primary factors. results reliability...
The effective chemotherapy of cancer is usually hindered by the unsatisfied cell internalization drug delivery systems (DDS) as well resistance cells. In order to solve these dilemmas in one design, red blood membrane (RBM)-coated silica nanoparticles (RS) were fabricated codeliver doxorubicin (Dox) and indocyanine green (ICG) effectively treat model lung using photothermal-assisted chemotherapy. Our results demonstrated that RS/I-D was nanoparticle at around 100 nm with superior stability...
This clinical study investigated plasma NT-proBNP levels as a potential predictor of heart failure in pediatric patients with sepsis. Plasma NT-ProBNP 211 sepsis and 126 healthy children were measured. Patients stratified (HF) or without (non-HF). graded having sepsis, severe septic shock. The optimal cut-off values for determined by analyzing the receiver operating characteristic (ROC). In HF, non-HF control groups, median 3640, 656, 226 ng/L, respectively. For all diagnostic value was 1268...
Anaplastic thyroid carcinoma is an aggressive variant of cancer that in most cases arises from anaplastic transformation terminally differentiated carcinomas. This process usually occurs the or cervical lymph nodes. distant metastatic sites exceedingly rare, only previously documented a few case reports. We report rare papillary within large retroperitoneal metastasis 64-year-old male 30 years after initial diagnosis.
Aim To examine the actual conditions of older patients receiving home medical care after hospitalization over a period 2 years in Japan. Methods The study population included 102 participants, aged ≥65 years, care, who consented to participate Osaka Home Care Registry (OHCARE) Japan years. We investigated for returning hospitalization. Results median age participants was 84 and 61 (59.8%) were women. In group that returned home, 42 (55.3%) respondents desired recuperate familiar place, as...
Backgrounds Effects of myocardial injury on E-selectin remain unclear. Thus, we investigated the diagnostic value for in paediatric patients with mycoplasma pneumoniae pneumonia. Methods In this prospective and blinded clinical study, plasma E-selectin, cardiac troponin I, creatine kinase isoenzyme MB, interleukin-6 tumor necrosis factor alpha concentrations were measured pneumonia (MPP group, n = 138). The control group comprised 120 healthy children. definition was based I or CK-MB (with...
Premonitory urges (PUs) was defined as the uncomfortable physical sensations of inner tension that can be relieved by producing movement responses. Nearly 70%-90% patients with Tourette syndrome reported experiences PUs.In this paper, we present two cases young PUs located in their tongue, which is very rare and easily misdiagnosed clinical work. Both complained an itchy tongue cannot help biting tongue. These were worth reporting because it initial symptom The results indicated seem to play...
BACKGROUND:Overexpression of p53, p21, and caspase-3 promotes apoptosis vascular smooth muscle cells. However, the mechanisms that lead to coronary artery cells (CASMCs) is unclear in Kawasaki disease (KD). This study investigated involvement CASMCs from a vasculitis mouse model. MATERIAL AND METHODS:The model with lesions was generated via administration Lactobacillus casei cell wall extract. In 2 groups mice (healthy control KD mice), levels protein root were evaluated...
We aimed to explore the correlations between eukaryotic translation initiation factor 3, subunit A (eIF3a) polymorphisms and susceptibility chemoradiotherapy efficacy in cervical carcinoma. Between August 2007 2011, 176 patients with carcinoma were enrolled as case group, 180 healthy individuals selected control group. eIF3a Arg803Lys C>T genotypes detected by hemi-nested polymerase chain reaction restriction fragment length polymorphism. All received evaluated for efficacy. Compared...