Simona De Vecchi
A5107998974- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac tumors and thrombi
- Intensive Care Unit Cognitive Disorders
- Pharmaceutical Practices and Patient Outcomes
- Cardiac Structural Anomalies and Repair
- COVID-19 and healthcare impacts
- Health Systems, Economic Evaluations, Quality of Life
- SARS-CoV-2 and COVID-19 Research
- Ultrasound in Clinical Applications
- Atrial Fibrillation Management and Outcomes
- Pulmonary Hypertension Research and Treatments
- COVID-19 and Mental Health
- Cardiovascular Issues in Pregnancy
- Myasthenia Gravis and Thymoma
- Respiratory Support and Mechanisms
- Connective tissue disorders research
- Parkinson's Disease and Spinal Disorders
- Thermal Regulation in Medicine
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2020-2025
Azienda Ospedaliera San Gerardo
2023
Istituti di Ricovero e Cura a Carattere Scientifico
2023
Fatebenefratelli Hospital
2023
Azienda Ospedaliero Universitaria Maggiore della Carita
2021-2022
Azienda Ospedaliera Ospedale Maggiore
2022
Regione Lazio
2016-2021
Ospedale degli Infermi
2019
<h3>Importance</h3> Although plenty of data exist regarding clinical manifestations, course, case fatality rate, and risk factors associated with mortality in severe coronavirus disease 2019 (COVID-19), long-term respiratory functional sequelae survivors COVID-19 are unknown. <h3>Objective</h3> To evaluate the prevalence lung function anomalies, exercise impairment, psychological among patients hospitalized for COVID-19, 4 months after discharge. <h3>Design, Setting, Participants</h3> This...
Abstract Clinical features and natural history of coronavirus disease 2019 (COVID-19) differ widely among different countries during phases the pandemia. Here, we aimed to evaluate case fatality rate (CFR) identify predictors mortality in a cohort COVID-19 patients admitted three hospitals Northern Italy between March 1 April 28, 2020. All these had confirmed diagnosis SARS-CoV-2 infection by molecular methods. During study period 504/1697 died; thus, overall CFR was 29.7%. We looked for...
A significant number of people, following acute SARS-CoV-2 infection, report persistent symptoms or new that are sustained over time, often affecting different body systems. This condition, commonly referred to as Long-COVID, requires a complex clinical management. In Italy health facilities specifically dedicated the diagnosis and care Long-COVID were implemented. However, activity these centers is highly heterogeneous, with wide variation in type services provided, specialistic expertise...
Introduction. The clinical course of Coronavirus Disease 2019 (COVID-19) is highly heterogenous, ranging from asymptomatic to fatal forms. identification and laboratory predictors poor prognosis may assist clinicians in monitoring strategies therapeutic decisions. Materials Methods. In this study, we retrospectively assessed the prognostic value a simple tool, complete blood count, on cohort 664 patients ( <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mi>F</mi> </math> 260; 39%,...
Clinical outcome data of patients discharged after Coronavirus disease 2019 (COVID-19) are limited and no study has evaluated predictors cardiovascular prognosis in this setting. Our aim was to assess short-term mortality hospitalization for COVID-19. A prospective cohort 296 consecutive COVID-19 from two Italian institutions during the first wave pandemic followed up 6 months included. The primary endpoint all-cause mortality. co-primary incidence composite major adverse cardiac...
Aims In the EXPLORER‐HCM trial, mavacamten reduced left ventricular outflow tract obstruction (LVOTO) and improved functional capacity of symptomatic hypertrophic obstructive cardiomyopathy (HOCM) patients. We sought to define potential use by comparing real‐world HOCM patients with those enrolled in assessing their eligibility treatment. Methods results collected information on followed up at 25 Italian HCM outpatient clinics significant LVOTO (i.e. gradient ≥30 mmHg rest or ≥50 after...
Post-acute sequelae of SARS-CoV-2 infection (PASC), commonly known as 'Long COVID-19', are progressively emerging in the population. While it was clear from pandemic outbreak that pre-existing cardiac conditions were exacerbated by even after its resolution, little is about rare cases de novo heart failure onset, whose mechanisms still not fully understood. A 74-year-old man admitted to emergency department with bilateral interstitial pneumonia at computed tomography scan. few months after,...
Abstract Objective The Marfan syndrome (MFS) is an autosomal dominant disorder of connective tissue resulting from pathogenic variants the fibrillin-1 gene (FBN1) with skeletal, cardiac, and ocular involvement. Study Design We report on a full-term male neonate, who showed at birth characteristics dysmorphisms suggestive nMFS, combined detection severe cardiovascular disease. A multidisciplinary team made up neonatologists pediatricians, cardiologists, geneticists, ophtalmologists,...
Background: The Italian Society of Echocardiography and Cardiovascular Imaging (SIECVI) conducted a national survey to understand better how different echocardiographic modalities are used accessed in Italy. Methods: We analyzed echocardiography laboratory activities over month (November 2022). Data were retrieved via an electronic based on structured questionnaire, uploaded the SIECVI website. Results: obtained from 228 laboratories: 112 centers (49%) northern, 43 (19%) central, 73 (32%)...
Abstract Background: The Italian Society of Echography and Cardiovascular Imaging (SIECVI) conducted a national survey to understand the volumes activity, modalities stressors used during stress echocardiography (SE) in Italy. Methods: We analyzed laboratory activities over month (November 2022). Data were retrieved through an electronic based on structured questionnaire, uploaded SIECVI website. Results: obtained from 228 echocardiographic laboratories, SE examinations performed 179 centers...
Background: Echocardiographic Pulmonary to Left Atrial Ratio (ePLAR) represents an accurate and sensitive non-invasive tool estimate the trans-pulmonary gradient. The prognostic value of ePLAR in hospitalized patients with COVID-19 remains unknown. We aimed investigate predictive on in-hospital mortality COVID-19. Methods: One hundred consecutive admitted two Italian institutions for undergoing early (<24 h) echocardiographic examination were included; was determined from maximum tricuspid...
Abstract Functional mitral regurgitation (FMR) is defined as with structurally normal leaflets secondary to the distortion of LV in context dilated cardiopathy. The conflicting results emerged from MITRA–FR and COAPT trials have raised a new interest individuation “primary–like” components MR. In this scenario, binary classification proportionate disproportionate FMR has been proposed by Garland et al. When MR completely due remodeling, they observed linear relationship between ERO LVEDV,...
Abstract Background. The incidence of cardiac implantable electronic device (CIED) implantation is currently growing. Patients who develop a moderate to severe CIED-induced tricuspid regurgitation (TR) are at higher risk pulmonary hypertension, right heart failure (HR) and have mortality. Transthoracic echocardiography (TTE) the most common method for TR grading, while transesophageal (TOE) with three-dimensional (3D) imaging nowadays gaining importance reconstruct valve morphology determine...
Abstract A 71-year-old male with no cardiovascular risk factors and a history of two uninvestigated episodes loss consciousness one year before, presented in our department to undergo treadmill exercise stress test relation inverted T waves V5-V6 on his basal ECG frequent ventricular extrasystoles (PVCs). The was positive for inducible ischemia, significant depression the ST-segment lateral lead. transthoracic echocardiography revealed normal thicknesses volumes left ventricle (LV)...