A5024374075- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Atrial Fibrillation Management and Outcomes
- Ion channel regulation and function
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- ECG Monitoring and Analysis
- Long-Term Effects of COVID-19
- Acute Myocardial Infarction Research
- Cardiac Structural Anomalies and Repair
- Neurological disorders and treatments
- Vasculitis and related conditions
- SARS-CoV-2 and COVID-19 Research
- Venous Thromboembolism Diagnosis and Management
- Nutritional Studies and Diet
- Sports injuries and prevention
- Heart Failure Treatment and Management
- Nuclear Structure and Function
- Cardiac Valve Diseases and Treatments
Instituto de Investigación Biosanitaria de Granada
2015-2025
Hospital Universitario Virgen de las Nieves
2014-2025
Universidad de Granada
2020-2022
Hospital Clínico Universitario Lozano Blesa
2022
KU Leuven
2022
Universidad de Navarra
2020
Navarre Institute of Health Research
2020
Complejo Hospitalario Universitario de Granada
2015-2017
Age and comorbidities increase COVID-19 related in-hospital mortality risk, but the extent by which mediate impact of age remains unknown.In this multicenter retrospective cohort study with data from 45 Dutch hospitals, 4806 proven patients hospitalized in hospitals (between February July 2020) CAPACITY-COVID registry were included (age 69[58-77]years, 64% men). The primary outcome was defined as a combination or discharge palliative care. Logistic regression analysis performed to analyze...
BACKGROUND: Less than 40% of patients with dilated cardiomyopathy (DCM) have a pathogenic/likely pathogenic genetic variant identified. TBX20 has been linked to congenital heart defects; although an association left ventricular noncompaction (LVNC) and DCM proposed, it is still considered gene limited evidence for these phenotypes. This study sought investigate the between truncating ( TBX20tv ) DCM/LVNC. METHODS: was sequenced by next-generation sequencing in 7463 unrelated probands...
Background Calmodulin 1, 2 and 3 (CALM) mutations have been found to cause cardiac arrest in children at a very early age. The underlying aetiology described is long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT) idiopathic fibrillation (IVF). Little phenotypical data about CALM2 available. Objectives aim of this paper describe the clinical manifestations Asn98Ser mutation two unrelated southern Spain with apparently unexplained arrest/death. Methods Two...
Abstract Introduction Cryoablation is an available tool for therapy the substrate of supraventricular tachycardia (SVT) located close to specific conduction system, due its lower risk atrioventricular block compared radiofrequency. Traditionally, this ablation guided by fluoroscopy, exposing patients and healthcare profesionals radiation. The electroanatomic map (EAM)-guided cryoablation modality achieved connecting catheter channel a standard tetrapolar catheter, which allows visualization...
IntroductionWe functionally analyzed a frameshift mutation in the SCN5A gene encoding cardiac Na+ channels (Nav1.5) found proband with repeated episodes of ventricular fibrillation who presented bradycardia and paroxysmal atrial fibrillation. Seven relatives also carry showed Brugada syndrome an incomplete variable expression. The (p.D1816VfsX7) resulted severe truncation (201 residues) Nav1.5 C-terminus. Methods ResultsWild-type (WT) mutated together hNavβ1 were expressed CHO cells currents...
Abstract SARS-CoV-2 is a rapidly evolving pandemic causing great morbimortality. Medical therapy with hydroxicloroquine, azitromycin and protease inhibitors being empirically used, reported data of QTc interval prolongation. Our aim to assess QT behaviour in not critically ill monitored cohort patients. We evaluated admitted ambulatory patients COVID-19 12 lead electrocardiogram at 48 h after treatment initiation. Other clinical analytical variables were collected. Statistical analysis was...
Background The Prevention With Mediterranean Diet (PREDIMED) trial supported the effectiveness of a nutritional intervention conducted by dietitian to prevent cardiovascular disease. However, effect remote follow diet has been less explored. Objective This study aims assess remotely provided diet–based in obtaining favorable dietary changes context secondary prevention atrial fibrillation (AF). Methods PREvention recurrent arrhythmias with (PREDIMAR) is 2-year multicenter, randomized,...
Introduction Cardiac channelopathies are a frequent cause of sudden cardiac death (SCD) and often manifest with convulsive syncope, leading to misdiagnosis epilepsy. We aim evaluate the clinical impact epilepsy in cohort patients channelopathies. Methods Fifty probands/families channelopathy were included. retrospectively collected information from medical records identify all who presented syncope diagnosed after neurological evaluation. Clinical data outcome compared those without previous...
Abstract The treatment of patients with bifascicular block (BFB) and syncope in the absence structural heart disease (SHD) is not well defined. objective our study to compare pacemaker empirical implantation use electrophysiological studies (EPS). This a prospective cohort that included 77 unexplained cardiogenic BFB without between 1997 2012. Two groups: 36 received pacemakers (Group A) 41 underwent EPS B) guide their treatment. incidence recurrence atrioventricular was lower group A....