A5103193675- Essential Oils and Antimicrobial Activity
- Synthesis and biological activity
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Crystallization and Solubility Studies
- Enzyme Structure and Function
- Protein Structure and Dynamics
- Computational Drug Discovery Methods
- Synthesis and Biological Evaluation
- Natural Antidiabetic Agents Studies
- Click Chemistry and Applications
- Cancer therapeutics and mechanisms
- Psidium guajava Extracts and Applications
- Bioactive Compounds and Antitumor Agents
- Carbohydrate Chemistry and Synthesis
- Synthesis and Characterization of Heterocyclic Compounds
- Phenothiazines and Benzothiazines Synthesis and Activities
- Medicinal Plants and Neuroprotection
- Free Radicals and Antioxidants
- Toxin Mechanisms and Immunotoxins
- Natural product bioactivities and synthesis
- Medicinal Plant Research
- Proteins in Food Systems
- Date Palm Research Studies
- Enzyme Production and Characterization
Al Baha University
2015-2024
University of Sfax
2015-2024
Indian Medical Association
2023-2024
École Nationale Supérieure Agronomique
2022
Qassim University
2021
University of Sadat City
2020
Centre of Biotechnology of Sfax
2017
Government Medical College
2013
University of Gabès
2011
Institut de Biologie Moléculaire et Cellulaire
2002-2005
This study aimed to investigate and compare the total phenolic content (TPC) flavonoid (TFC) antioxidant antibacterial activities of different extracts recovered from Date Palm Pollen collected Tunisian cultivars Kerkennah (DPP-K) Tozeur (DPP-T) using various solvents, including hexane, chloroform, ethyl acetate, acetone, ethanol water. The results revealed that DPP-T had higher TPC than DPP-K for all solvent extracts, except with a value 237.74 ± 9.58 mg GAE/g water extract. highest level...
Ecballium elaterium is a perennial herb with multiple medicinal properties. It was widely used in folk medicine as cathartic, anti-inflammatory and analgesic agents. The present study devoted to investigate the effect of diethyl ether, acetone, methanol solvent on extraction, phytochemicals profiles, antioxidant antimicrobial activities seeds peels fruits. total phenolic, flavonoid, flavonol, condensed tannins carotenoids contents were estimated. Maximum phenolic (107 ± 4 mg GAE/g) flavonoid...
In order to validate its antiseptic and anticancer properties with respect traditional uses, we have screened for the first time antimicrobial activity of aerial parts M. vulgare L. essential oil against different pathogenic microorganisms cytotoxic HeLa cell lines.The agar disk diffusion method was used study antibacterial 12 bacterial 4 fungi strains. The disc diameters zone inhibition (DD), minimum inhibitory concentrations (MIC) concentration inhibiting 50% (IC50) were investigated...
Herbs and spices have been used since antiquity for their nutritional health properties, as well in traditional remedies the prevention treatment of many diseases. Therefore, this study aims to perform a chemical analysis both essential oils (EOs) from seeds Carum carvi (C. carvi) Coriandrum sativum sativum) evaluate antioxidant, antimicrobial, anti-acetylcholinesterase, antidiabetic activities alone combination. Results showed that EOs mainly constitute monoterpenes with γ-terpinene...
Considering the current dramatic and fatal situation due to high spreading of SARS-CoV-2 infection, there is an urgent unmet medical need identify novel effective approaches for prevention treatment Coronavirus disease (COVID 19) by re-evaluating repurposing known drugs. For this, tomatidine patchouli alcohol have been selected as potential drugs combating virus. The hit compounds were subsequently docked into active site molecular docking analyses revealed that both can bind 3CLpro, PLpro,...
Piper cubeba L. fruit is an important species used in folk medicine for different types of pains such as rheumatism, chills, flu, colds, muscular aches, and fever. This study examines the chemical constituents, antioxidant activity, potential inhibitory effect against human peroxiredoxin 5, a key enzyme P. essential oil from fruits. Using gas chromatography coupled with mass spectrometry (GC-MS), principal components were methyleugenol (41.31%) eugenol (33.95%), followed by (E)-caryophyllene...
This research study examines academic self-perceptions and course satisfaction among university students associated factors during virtual classes. A cross-sectional online survey of (n = 328) undergraduate postgraduate Saudi who took classes the second semester year 2019–2020 first 2020–2021 coronavirus disease 2019 (COVID-19) pandemic. The findings demonstrated students’ scores on negative (mean (M) 9.84; standard deviation (S.D.) 3.09) are significantly higher in comparison to positive (M...
Anethum graveolens L. has been known as an aromatic, medicinal, and culinary herb since ancient times. The main purpose of this study was to determine the chemical composition, antibacterial, antibiofilm, anti-quorum sensing activities essential oil (EO) obtained by hydro-distillation aerial parts. Twelve components were identified, representing 92.55% analyzed oil. Limonene (48.05%), carvone (37.94%), cis-dihydrocarvone (3.5%), trans-carvone (1.07%) identified constituents. Results showed...
A novel isoxazolidine derivative (ISoXD) dye was successfully synthesized and comprehensively characterized. In this study, we conducted a thorough examination of its various properties, including optical characteristics, interactions with DNA β-cyclodextrin (β-CD), molecular docking, dynamic simulation, density functional theory (DFT) calculations. Our investigation encompassed systematic analysis the absorption emission spectra ISoXD in diverse solvents. The observed variations...
The aim of the present study was to appraise antimicrobial activity Ricinus communis L. essential oil against different pathogenic microorganisms and cytotoxic HeLa cell lines.The agar disk diffusion method used antibacterial 12 bacterial 4 fungi strains. disc diameters zone inhibition (DD), minimum inhibitory concentrations (MIC) concentration inhibiting 50% (IC50) were investigated characterize activities this oil. in vitro cytotoxicity examined using a modified MTT assay; viability IC50...
For the first time, we reported phytochemical composition of volatile oil from Thymus musilii Velen (T. musilii). The antioxidant and antimicrobial activities against various food-borne clinical pathogenic microorganisms were also tested. thyme was particularly rich in thymol (67.697 ± 0.938%), thymyl acetate (12.993 0.221%). strongest activity essential registered with tests: ABTS (IC50 = 5.6 × 10−4 mg/mL) β-carotene/linoleic acid 3.2 10−3 mg/mL). This thymol-chemotype active all tested an...
In vitro cytotoxicity and druglikeness of pyrazolines pyridines bearing benzofuran moietyAsma S. Al Wasidi, Ashraf Hassan, Ahmed M. Naglah
This study investigated
In an attempt to rationalize the search for new potential anti-inflammatory and anti-infection agents, a series of 1,4-and 1,5-disubstituted 1,2,3-triazoles linked benzoxazine conjugates have been synthesized via "Click Chemistry" reaction, were designed, characterized by means spectral elemental data. The newly compounds assessed their antimicrobial, antioxidant potential. Results revealed that all display superior activities standard drug against different bacterial strains especially S....
Clinical multi-drug-resistant bacteria continue to be a serious health problem. Plant-derived molecules are an important source of bioactive compounds counteract these pathogenic bacteria. In this paper, we studied the chemical composition methanol (80%) extract from Pithecellobium dulce seed (Hail, Saudi Arabia) and its ability inhibit growth clinically relevant Molecular docking analysis was performed predict best with low binding energy high affinity interact two Staphylococcus aureus...
Isoxazolidine derivatives were designed, synthesized, and characterized using different spectroscopic techniques elemental analysis then evaluated for their ability to inhibit both α-amylase α-glucosidase enzymes treat diabetes. All synthesized demonstrated a varying range of activity, with IC
In the development of novel antidiabetic agents, a series isoxazolidine-isatin hybrids were designed, synthesized, and evaluated as dual α-amylase α-glucosidase inhibitors. The precise structures synthesized scaffolds characterized using different spectroscopic techniques elemental analysis. obtained results compared to those reference drug, acarbose (IC
Background: The study aimed to assess the antioxidant and wound healing properties of Urtica dioica essential oil (UDEO) through a comprehensive evaluation involving in silico, vitro, vivo analyses. phytochemistry UDEO was also investigated identify trace compounds crucial. Methods: Various injection methods multimode inlet (MMI) chromatography were attain lower instrumental detection limits. Subsequently, silico studies employed delve deeper into potential biological activities identified...