Chunhui Qiu

ORCID: 0000-0003-4757-7782
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Research Areas
  • Advanced Differential Geometry Research
  • Geometric Analysis and Curvature Flows
  • Holomorphic and Operator Theory
  • Parasites and Host Interactions
  • Geometry and complex manifolds
  • Algebraic and Geometric Analysis
  • Research on Leishmaniasis Studies
  • Meromorphic and Entire Functions
  • RNA modifications and cancer
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Advanced Harmonic Analysis Research
  • Nonlinear Partial Differential Equations
  • Trace Elements in Health
  • Advanced Mathematical Modeling in Engineering
  • Mathematical functions and polynomials
  • Advanced Algebra and Geometry
  • Algebraic Geometry and Number Theory
  • Differential Equations and Boundary Problems
  • Analytic and geometric function theory
  • Spectral Theory in Mathematical Physics
  • Circular RNAs in diseases
  • Vitamin K Research Studies
  • Nonlinear Waves and Solitons
  • Advanced Topics in Algebra

Xiamen University
2014-2025

Third Affiliated Hospital of Sun Yat-sen University
2011-2024

Sun Yat-sen University
2011-2024

Guangzhou Medical University
2021

First Affiliated Hospital of Guangzhou Medical University
2021

Sun Yat-sen Memorial Hospital
2021

China Academy Of Machinery Science & Technology (China)
2016

Chinese Academy of Agricultural Sciences
2010-2015

Fujian Agriculture and Forestry University
2010-2015

Shanghai Veterinary Research Institute
2010-2015

Long non-coding RNAs (lncRNAs) have been known to partake in the development and immune escape of hepatocellular carcinoma (HCC). The initial microarray analysis GSE115018 expression profile revealed differentially expressed lncRNA fetal-lethal developmental regulatory RNA (FENDRR) HCC. Therefore, this study's main purpose was explore mechanism tumor suppressor FENDRR regulating HCC cells. Notably, it further validated through study that competitively bound microRNA-423-5p (miR-423-5p),...

10.1016/j.omtn.2019.05.027 article EN cc-by-nc-nd Molecular Therapy — Nucleic Acids 2019-06-12

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). retracted at the request of editors. Concerns regarding data integrity, which were based a PubPeer thread showing unusually structured flow cytometry plots and an acknowledgements statement that appeared in multiple paper mill papers (https://pubpeer.com/publications/5BDD7EDBC667C3CAD70F57F88FC657), raised by National Science Library Chinese Academy Sciences....

10.1016/j.omtn.2019.10.035 article EN cc-by-nc-nd Molecular Therapy — Nucleic Acids 2019-11-13

The interplay between sexes is a prerequisite for female growth, reproductive maturation, and egg production, the basis of schistosome pathopoiesis propagation. tegument in direct contact with host environment its surface membranes are particularly crucial survival definitive host. In this study, streptavidin–biotin affinity purification technique combined LC–MS/MS was used to analyze putative tegument-exposed proteins male adult Schistosoma japonicum worms. total, 179 were identified...

10.1021/pr400476a article EN Journal of Proteome Research 2013-08-02

10.1007/s00526-024-02916-0 article EN other-oa Calculus of Variations and Partial Differential Equations 2025-01-06

Retinoic acid receptor-related receptor alpha (RORalpha) has been proven to play a tumor suppressive role in certain types of solid tumors. However, the clinical characteristic RORalpha not reported by far. This study investigated expression hepatocellular carcinoma (HCC) and evaluated its relationship with parameters prognosis HCC patients. Quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) Western blot analyses were performed detect levels 20 paired corresponding...

10.1007/s13277-014-2007-9 article EN Tumor Biology 2014-05-05

In this study, the authors address design of optimal waveform for detecting extended target in signal-dependent interference, using probability detection as a cost function. The model received signal frequency domain and derive optimum Neyman–Pearson (NP) detector. Considering distribution test statistic is rather complicated, use mathematically tractable form to approximate an analytical expression with regard transmitted waveform. This lays foundation subsequent optimisation. Finally,...

10.1049/iet-rsn.2010.0275 article EN IET Radar Sonar & Navigation 2012-01-01

Integrator complex subunit 6 (INTS6) was found to play a tumour suppressing role in certain types of solid tumours. In this study, we wanted determine the expression level INTS6 hepatocellular carcinoma (HCC) and evaluate its clinical characteristics mechanisms HCC patients (Lui Lu, European Journal Cancer, 51:S94, 2015).First, used microarray analysis explore mRNA levels paired normal liver tissues; second, qRT-PCR measure cohort 50 tissues adjacent third, Western blot analyses detect...

10.1186/s12885-017-3628-3 article EN cc-by BMC Cancer 2017-09-12

Primary hepatic neuroendocrine tumors (PHNETs) are rare malignant liver that present diagnostic challenges owing to their rarity and absence of specific clinical features. This study aimed investigate the characteristics this tumor enhance our understanding disease, improve accuracy, explore standardized treatment approaches.During physical examination, two elderly women, aged 64 74 years, were found have masses. 18F-FDG Positron Emission Tomography-Computed Tomography (18F-FDG PET-CT)...

10.3389/fonc.2023.1225583 article EN cc-by Frontiers in Oncology 2023-08-04

We analyzed proteins that were differentially expressed by 10-day-old schistosomula from 3 different hosts and determined a functional thioredoxin peroxidase-2 gene has an important antioxidant role in Schistosoma japonicum, which we investigated further. A full-length cDNA encoding the S. japonicum (SjTPx-2) had open reading frame of 681 bp encoded 226 amino acids with signal peptide 24 acids. SjTPx-2 without sequence was isolated 42-day-old schistosome cDNAs. Real-time quantitative RT-PCR...

10.1645/ge-3096.1 article EN Journal of Parasitology 2013-02-01

In this study, we aimed to determine whether the pseudogene integrator complex subunit 6 1 (INTS6P1) in plasma could be used as a novel approach screen for and detect hepatocellular carcinoma (HCC). We explored clinical role of INTS6P1: First, expression level INTS6P1 was measured cohort 33 HCC tissue samples adjacent normal liver tissue, next, detected culture medium tumor cells cellular experiment, last, diagnostic performance examined an independent 100 people. The remarkably...

10.1007/s13277-015-3899-8 article EN Tumor Biology 2015-08-18

Abstract Background Thyroid hormones (TH) modulate growth, development and differentiation metabolic processes by interacting with thyroid hormone receptors (THRs). The purpose of this study was to identify a novel receptor beta encoding gene Schistosoma japonicum (SjTHRβ) investigate its potential as vaccine candidate antigen against schistosomiasis in BALB/c mice. Methods full-length cDNA sequence SjTHRβ, organization, transcript levels were characterized, the phylogenetic relationship...

10.1186/1756-3305-5-172 article EN cc-by Parasites & Vectors 2012-08-13

Leucocytozoon parasites infect many species of avian hosts, including domestic chicken, and can inflict heavy economic loss to the poultry industry. Although prevalence distribution two (L. sabrazesi L. caulleryi) have been reported in China previously, there are questions related parasite infection that remain unanswered, population diversity transmission dynamics chickens. Here we surveyed chicken blood samples from seven sites four provinces identify infection, characterized within...

10.1371/journal.pone.0094877 article EN cc-by PLoS ONE 2014-04-11

10.1016/s0252-9602(10)60025-2 article EN Acta Mathematica Scientia 2010-01-01

10.1016/j.aim.2018.11.008 article EN publisher-specific-oa Advances in Mathematics 2018-12-04

Schistosomiasis, caused by infection with <i >Schistosoma</i> species, remains an important parasitic zoonosis. Thioredoxin glutathione reductase of >Schistosoma japonicum </i>(SjTGR) plays role in the development parasite and for its survival. Here we present a recombinant plasmid DNA vaccine, pVAX1/SjTGR, to estimate protection against >S. japonicum</i> BALB/c mice. The vaccine administrated particle bombardment induced higher than intramuscular injection. All animals vaccinated...

10.1155/2013/952416 article EN cc-by BioMed Research International 2012-12-31

Background and AimsHepatic ischemia-reperfusion injury (HIRI) is a prevalent complication of liver transplantation, partial hepatectomy, severe infection, necessitating the development more effective clinical strategies. Receptor activity–modifying protein 1 (RAMP1), member G protein–coupled receptor adapter family, has been implicated in numerous physiological pathological processes. The study aimed to investigate pathogenesis RAMP1 HIRI.

10.14218/jcth.2023.00339 article EN Journal of Clinical and Translational Hepatology 2024-02-29

Let M be a compact complex manifold with Finsler metric F. We define natural projection of horizontal Laplacian on M: it is independent the fiber coordinate. By using Sobolev space theory and spectral resolution in Hilbert space, we prove Hodge theorem for M.

10.1016/j.difgeo.2014.01.012 article EN publisher-specific-oa Differential Geometry and its Applications 2014-02-15

The boundedness and compactness of the weighted composition followed andproceeded by differentiation operators from Zygmund spaces to Bloch-type spacesand little are characterized. MSC: 47B38, 30H30, 32C15.

10.1186/1029-242x-2014-152 article EN cc-by Journal of Inequalities and Applications 2014-05-02

10.1007/s11401-011-0661-4 article EN Chinese Annals of Mathematics Series B 2011-07-01
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