Marian Klinger
A5056125023- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Renal Diseases and Glomerulopathies
- Central Venous Catheters and Hemodialysis
- Dialysis and Renal Disease Management
- Vascular Procedures and Complications
- Renal and Vascular Pathologies
- Neurological Complications and Syndromes
- Transplantation: Methods and Outcomes
- Organ Donation and Transplantation
- Pharmacological Effects and Toxicity Studies
- Vasculitis and related conditions
- Urticaria and Related Conditions
- Systemic Lupus Erythematosus Research
- Pregnancy and Medication Impact
- Polyomavirus and related diseases
- Chronic Kidney Disease and Diabetes
- Cytomegalovirus and herpesvirus research
- T-cell and B-cell Immunology
- Vascular anomalies and interventions
- Organ and Tissue Transplantation Research
- Acute Kidney Injury Research
- Immune Cell Function and Interaction
- Parathyroid Disorders and Treatments
- Viral-associated cancers and disorders
University of Opole
2019-2023
Wroclaw Medical University
2012-2021
Uniwersytecki Szpital Kliniczny w Opolu
2019-2020
Istituto di Fisiologia Clinica
2016
Medical University of Silesia
2016
University of Wrocław
2002-2014
Niepubliczna Wyższa Szkoła Medyczna
1994-2014
Poznań University of Technology
2011-2012
Phoenix Contact (United States)
2011-2012
University of Bydgoszcz
2011-2012
Background and objectives Accumulation of fluid in the lung is most concerning sequela volume expansion patients with ESRD. Lung auscultation recommended to detect monitor pulmonary congestion, but its reliability ESRD unknown. Design, setting, participants, & measurements In a subproject ongoing Water by Ultra-Sound Guided Treatment Prevent Death Cardiovascular Complications High Risk Patients Cardiomyopathy Trial, we compared ultrasound–guided ultrafiltration prescription policy versus...
<b><i>Background/Aims: </i></b>The aim of the study was to evaluate effects a six-month physical training undertaken by haemodialysis (HD) patients, on depression and anxiety. <b><i>Methods: </i></b>Patients with end stage renal disease (ESRD) were recruited from dialysis station at Department Nephrology Transplantation Medicine in Wroclaw. Physical took place beginning first 4-hours dialysis, three times week for six months. A personal...
Chronic kidney disease (CKD) is a prevalent cause of morbidity and mortality worldwide. A hallmark CKD progression renal fibrosis characterized by excessive accumulation extracellular matrix (ECM) proteins. In this study, we aimed to investigate the correlation urinary proteome classifier CKD273 individual peptides with degree fibrosis. total, 42 biopsies urine samples were examined. The percentage per total tissue area was assessed in Masson trichrome stained tissues. analysed capillary...
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are a group of pauci-immune small vessel that often affect the kidneys manifesting as rapidly progressive glomerulonephritis. Although exact pathogenesis AAV is not fully known, evidence from in vitro, vivo and clinical studies all point to involvement ANCA AAV. In this review, we highlight contributory roles played by various factors (e.g. genetics, environment, B T-regulatory cells, toll-like receptors, etc.)...
Within the framework of LUST trial (LUng water by Ultra-Sound guided Treatment to prevent death and cardiovascular events in high-risk end-stage renal disease patients), European Renal Cardiovascular Medicine (EURECA-m) working group Association–European Dialysis Transplant Association established a central core lab aimed at training certifying nephrologists cardiologists participating this trial. All participants were trained an expert trainer with entirely web-based programme. Thirty 14...
Background. The side effects associated with corticosteroids have led to efforts minimize their use in renal transplant patients. In this study we compared two corticosteroid-free tacrolimus-based regimens a standard triple therapy. Methods. This was 6-month, phase III, open-label, parallel-group, multicenter study. total analysis set comprised 451 patients, randomized (1:1:1) receive tacrolimus (Tac) monotherapy following basiliximab (Bas) administration (n=153), Tac/mycophenolate mofetil...
Non-HLA antibodies (Abs) targeting vascular receptors are considered to have an influence on renal transplant injury. Anti-endothelin-1 type A receptor (anti-ETAR) were associated with cellular and antibody-mediated rejection early onset of vasculopathy in heart patients but their role transplantation remains unclear. The aim our study was assess the incidence importance anti-ETAR impact during first year observation.We evaluated presence 116 consecutive recipients pre- post-transplant...
BackgroundKidney recipients maintaining a prolonged allograft survival in the absence of immunosuppressive drugs and without evidence rejection are supposed to be exceptional. The ERA-EDTA-DESCARTES working group together with Nantes University launched European-wide survey identify new patients, describe them estimate their frequency for first time.
Long-term use of corticosteroids is associated with considerable morbidity, including cardiovascular and metabolic adverse effects.This study evaluated the long-term efficacy safety two steroid-free regimens compared a triple immunosuppressive therapy in renal transplant recipients. This was 3-year follow-up to 6-month, open-label, randomized, multicenter study.Data from 3 years were available for 421 (93.3%) 451 patients original intent-to-treat population (143 tacrolimus/basiliximab...
This is the first report on epidemiology of biopsy-proven kidney diseases in Poland.The Polish Registry Renal Biopsies has collected information all (n = 9394) native renal biopsies performed Poland from 2009 to 2014. Patients' clinical data at time biopsy, and histopathological diagnoses were used for epidemiological clinicopathologic analysis.There was a gradual increase number per million people (PMP) year 2009-14, starting 36 PMP 44 A considerable variability between provinces mean...
Abstract Background Quality of life (QoL) is an important outcome in chronic kidney disease (CKD). Patients feel that symptoms are determinant QoL. However, this relation unknown. The aims study were to investigate the impact number and severity on QoL elderly pre-dialysis patients, assessed by both effect their importance relative function, other clinical variables Methods European (EQUAL study) ongoing prospective follow-up late Stage 4/5 CKD patients aged ≥65 years. We used included...
In animal and in vitro models, FK778 inhibits acute rejection, modifies vasculopathy, shows anti-viral activity. We report first efficacy safety data of human kidney transplant recipients at two concentration-controlled ranges.In a double-blind manner, 149 patients were randomized to 12-week treatment with combination tacrolimus (Tac) corticosteroids (S). Of the high-level group (H), 49 received 2 x 600 mg/day continued on 150 mg/day, 54 low-level (L) got 1 followed by 75 46 placebo (P)....