Sophie Thorn
A5004451331- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Trauma and Emergency Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Blood transfusion and management
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood donation and transfusion practices
- Cardiac Arrest and Resuscitation
- Acute Ischemic Stroke Management
- Pelvic and Acetabular Injuries
- Venous Thromboembolism Diagnosis and Management
Alfred Health
2020-2022
Monash University
2019-2022
Witten/Herdecke University
2019
Summary Coagulopathy in patients with traumatic brain injury is associated an increase morbidity and mortality. Although timely aggressive treatment of coagulopathy paramount importance, excessive transfusion blood products has been linked poor long‐term outcomes injury. A point‐of‐care thromboelastometric‐guided algorithm could assist creating a more individually tailored approach to each patient. The aim this study was evaluate the feasibility implementing centres that were formerly naïve...
Abstract Background Trauma-induced coagulopathy in patients with traumatic brain injury (TBI) is associated high rates of complications, unfavourable outcomes and mortality. The mechanism the development TBI-associated poorly understood. Methods This analysis, embedded prospective, multi-centred, observational Collaborative European NeuroTrauma Effectiveness Research Traumatic Brain Injury (CENTER-TBI) study, aimed to characterise TBI. Emphasis was placed on acute phase following TBI,...
Abstract Background Trauma-induced coagulopathy in traumatic brain injury (TBI) remains associated with high rates of complications, unfavorable outcomes, and mortality. The underlying mechanisms are largely unknown. Embedded the prospective multinational Collaborative European Neurotrauma Effectiveness Research Traumatic Brain Injury (CENTER-TBI) study, coagulation profiles beyond standard conventional assays were assessed patients isolated TBI within very early hours injury. Methods...
Purpose Early identification of trauma patients at risk developing acute traumatic coagulopathy is important in initiating appropriate, coagulopathy-focused treatment. A clinical prediction tool a quick, simple method to evaluate risk. The COAST score was developed Australia and we hypothesised that it could predict bleeding-related adverse outcomes other advanced systems. We validated on single-centre cohort from centre Belgium. Methods modified suit available data; used entrapment, blood...