A5100733648- Advanced biosensing and bioanalysis techniques
- Carbon and Quantum Dots Applications
- Luminescence and Fluorescent Materials
- Nanocluster Synthesis and Applications
- Cancer-related molecular mechanisms research
- Biosensors and Analytical Detection
- Molecular Sensors and Ion Detection
- Ideological and Political Education
- Antibiotic Resistance in Bacteria
- Advanced Nanomaterials in Catalysis
- MicroRNA in disease regulation
- Hydrogen Storage and Materials
- Circular RNAs in diseases
- Advancements in Transdermal Drug Delivery
- Electrochemical sensors and biosensors
- Clostridium difficile and Clostridium perfringens research
- RNA Interference and Gene Delivery
- MXene and MAX Phase Materials
- Advanced Battery Materials and Technologies
- Catalytic Cross-Coupling Reactions
- Ammonia Synthesis and Nitrogen Reduction
- Quantum Dots Synthesis And Properties
- Coordination Chemistry and Organometallics
- Catalysis and Oxidation Reactions
- Infections and bacterial resistance
Southeast University
2024
Southwest University
2014-2024
Dalian University
2023-2024
Second Affiliated Hospital of Jilin University
2009-2024
Yibin University
2024
Changhai Hospital
2024
Second Military Medical University
2024
First Affiliated Hospital of Wannan Medical College
2024
Chongqing University
2018-2023
Kunming Medical University
2023
Emerging antibiotic resistance threatens human health. Gut microbes are an epidemiologically important reservoir of genes (resistome), yet prior studies indicate that the true diversity gut-associated resistomes has been underestimated. To deeply characterize pediatric resistome, we created metagenomic recombinant libraries in Escherichia coli host using fecal DNA from 22 healthy infants and children (most without recent exposure), performed functional selections for to 18 antibiotics eight...
Novel two-dimensional Ti3C2 MXene nanosheets were successfully prepared by etching Al from Ti3AlC2 in LiF/HCl system. In order to further improve the dispersing property and electrical conductivity of nanosheets, Ti3C2/graphene oxide (Ti3C2-GO) nanocomposites synthesized applied for fabrication inkjet-printed hydrogen peroxide (H2O2) sensor. The results electrochemical characterization show that sensor maintains biological activity hemoglobin (Hb) can be practical detection. printed sensors...
Infections caused by antibiotic-resistant bacterial pathogens are a growing public health threat. Understanding of pathogen relatedness and biology is imperative for tracking outbreaks developing therapeutics. Here, we detail the phylogenetic structure 145 K. variicola genomes from different continents. Our results have important clinical ramifications as high-risk antibiotic resistance genes present in variety geographic locations demonstrate that isolates can establish higher bladder...
A high quantum yield (QY) is the key requirement for implementing carbon dots (CDs) in nearly all applications. In this work, blue emissive N-doped CDs with a QY of 83% and orange 47% were successfully prepared using resorcinol phloroglucin as resources formamide by one-step microwave synthesis, respectively. Formamide not only plays role solvent but also takes part formation CDs. It demonstrated that as-prepared blue- orange-emitting can be uniformly dispersed into glue fabricated CD/glue...
Quantum-dots (QDs) have fuelled up intensive research efforts over the past two decades. Nevertheless, currently developed classes of fluorescent QDs, colloidal semiconductor QDs and carbonaceous suffer from either toxicity or short luminescence lifetime. Here, we report a new class bio-dots that are derived DNA via self-assembly at low temperatures down to 80°C, which has an optical bandgap 3.4 eV in particular possesses strong photoluminescence with much longer lifetime (τ1 = 10.44 ns)...
In the present work, polyethylenimine-capped CdS quantum dots (PEI-CdS QDs) with bright green fluorescence were synthesized and applied for sensitively selectively detecting nitrite in vegetable water samples. Highly fluorescent environment-friendly PEI-CdS QDs (quantum yield about 8%) diameters of ca. 5 nm easily by using hyperbranched PEI as functional polymer. Formation was verified transmission electron microscopy UV-vis spectroscopy. The intensity as-synthesized enhanced pronouncedly...
Orange red-emitting CDs were constructed from 2,3-diaminopyridine and successfully used for visual colorimetry near-infrared cellular imaging.
Abstract Coated microneedles (CMNs) are a minimally invasive platform for immediate‐release transdermal drug delivery. However, the practical applications of CMNs have been significantly hindered by challenges associated with complex formulations, single function, and limited loading capacity. This study has developed spiderweb‐shaped iron‐coordinated polymeric nanowire network (Fe‐IDA NWs). The resulting Fe‐IDA NWs endowed certain viscosity due to synergy multiple supramolecular...
Abstract DNA molecules as storage media are characterized by high encoding density and low energy consumption, making a highly promising method. However, has shortcomings, especially when storing multimedia data, wherein image reconstruction fails address errors occur, resulting in complete data loss. Therefore, we propose parity local mean iteration (PELMI) scheme to achieve robust of images. The proposed satisfies the common biochemical constraints sequences undesired motif content. It...
The role of lncRNA KCNQ1 opposite strand/antisense transcript 1 (KCNQ1OT1) in colon cancer involves various tumorigenic processes and has been studied widely. However, the mechanism by which it promotes remains unclear. Retroviral vector pSEB61 was retrofitted established HCT116-siKCN SW480-siKCN cells to silence KCNQ1OT1. Cellular proliferation measured using CCK8 assay, flow cytometry (FCM) detected cell cycle changes. RNA sequencing (RNA-Seq) analysis showed differentially expressed genes...
Macrophages, the predominant immune cells in lungs, play a pivotal role maintaining delicate balance of pulmonary microenvironment. However, chronic inflammatory lung diseases and cancer, macrophage phenotypes undergo distinct transitions, with M1-predominant macrophages promoting damage M2-predominant fostering cancer progression. Exosomes, as critical mediators intercellular signaling substance exchange, participate pathological reshaping during development cancer. Specifically, diseases,...
A protocol for regio-controlled hydromagnesiation of 1,3-enynes was developed using magnesium hydride that is generated in situ by solvothermal treatment sodium (NaH) and iodide (MgI2 ) THF. The resulting allenylmagnesium species could be converted into tri- tetra-substituted allenes subsequent with various carbon- silicon-based electrophiles the aid CuCN as a catalyst.