A5106175111- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Livestock Farming and Management
- Genetic Mapping and Diversity in Plants and Animals
- melanin and skin pigmentation
- Livestock and Poultry Management
- Molecular Biology Techniques and Applications
- Animal Genetics and Reproduction
- Nutrition, Health and Food Behavior
- Bat Biology and Ecology Studies
- Animal Nutrition and Physiology
- Milk Quality and Mastitis in Dairy Cows
- Livestock Management and Performance Improvement
- Fungal and yeast genetics research
- Genetic diversity and population structure
- Food Quality and Safety Studies
- Agricultural Systems and Practices
- Evolution and Paleontology Studies
- Genomics and Phylogenetic Studies
- Agriculture, Soil, Plant Science
- Genetic Syndromes and Imprinting
- Human-Animal Interaction Studies
- Fungal Plant Pathogen Control
- Plant-Microbe Interactions and Immunity
China Agricultural University
2019-2025
Anhui Agricultural University
2025
Ministry of Agriculture and Rural Affairs
2020-2024
State Key Laboratory of Animal Nutrition
2020
Abstract Genetic introgression not only provides material for adaptive evolution but also confounds our understanding of evolutionary history. This is particularly true canids, a species complex in which genome sequencing and analysis has revealed history admixture introgression. Here, we sequence 19 new whole genomes from high-altitude Tibetan Himalayan wolves dogs combine these into larger data set 166 canid genomes. Using data, explore the adaptation other lineages. We find that are...
Abstract Visible pigmentation phenotypes can be used to explore the regulation of gene expression and evolution coat color patterns in animals. Here, we performed whole-genome RNA sequencing applied genome-wide association study, comparative population genomics biological experiments show that 2,809-bp-long LINE-1 insertion ASIP (agouti signaling protein) is causative mutation for white phenotype swamp buffalo (Bubalus bubalis). This (3′ truncated containing only 5′ UTR) functions as a...
Paper mulberry (Broussonetia papyrifera; PM) is an excellent and extensive type of roughage in Asia. This study aimed to evaluate the effects PM silage on milk production, apparent digestibility, antioxidant capacity, fecal bacteria composition Holstein dairy cows. Forty-five lactating cows with a similar yield parity were selected randomly assigned three groups. The control group was fed non-PM diet, PM-treated groups 4.5 9.0% supplementary diets for 28 days. Then, treatment containing 13.5...
Abstract Background Ketosis is a common metabolic disease during the transition period in dairy cattle, resulting long-term economic loss to industry worldwide. While genetic selection of resistance ketosis has been adopted by many countries, and biological basis underlying poorly understood. Results We collected total 24 blood samples from 12 Holstein cows, including 4 healthy 8 ketosis-diagnosed ones, before (2 weeks) after (5 days) calving, respectively. then generated RNA-Sequencing...
Household buffalo dairy farming is gaining popularity nowadays in Bangladesh because of the outstanding food value milk as well lower production cost compared to cattle. An initiative has recently been taken for genetic improvement indigenous buffaloes. The present study was carried out determine influence some environmental factors like age, parity, season calving, calving interval, dry period on lactation yield, and curve buffaloes Bangladesh. A total 384 from 3rd 4th parity seven herds...
We generated 73 transcriptomic data of water buffalo, which were integrated with publicly available in this species, yielding a large dataset 355 samples representing 20 major tissue categories. established multi-tissue gene expression atlas buffalo. Furthermore, by comparing them 4866 cattle from the genotype-tissue (CattleGTEx), we found that transcriptomes two species exhibited conservation their overall patterns, tissue-specific and house-keeping expression. further identified conserved...
Background/Objectives: Buffalo populations exhibit distinct genetic variations influenced by domestication history, geographic distribution, and selection pressures. This study investigates the structure differentiation of 11 buffalo populations, focusing on five loci related to milk protein (CSN1S1 CSN3) fat metabolism (LPL, DGAT1 SCD). The aim is assess variation between river, swamp, wild-type buffaloes identify key contributing population differentiation. Methods: Genetic diversity was...
Swamp-type buffaloes with varying degrees of white spotting are found exclusively in Tana Toraja, South Sulawesi, Indonesia, where spotted buffalo bulls highly valued accordance the Torajan customs. The depigmentation is caused by absence melanocytes. However, genetic variants that cause this phenotype have not been fully characterized. objective study was to identify genomic regions and responsible for unique coat-color pattern.
Abstract The application of high-throughput genotyping or sequencing data helps us to understand the genomic response natural and artificial selection. In this study, we scanned genomes five indigenous buffalo populations belong three recognized breeds, adapted different geographical agro-ecological zones in Iran, unravel extent diversity localize regions genes underwent past A total 46 river whole genomes, from West East Azerbaijan, Gilan, Mazandaran, Khuzestan provinces, were resequenced....
Indigenous buffaloes, as the important livestock species contributing to economy of country, are lifeline livelihood in Nepal. They distributed across diverse geographical regions country and have adapted various feeding, breeding, management conditions. The larger group these native buffalo breeds present narrow stiff hilly terrains. Their dispersal indicates a possible environmental adaptation mechanism, which is crucial for conservation breeds. We utilized whole-genome sequencing (WGS)...
Accurate breed classification is required for the conservation and utilization of farm animal genetic resources. Traditional methods mainly rely on phenotypic characterization. However, it difficult to distinguish between highly similar breeds due challenges in qualifying character. Machine learning algorithms show unique advantages using genomic information. To evaluate Chinese cattle breeds, this study utilized SNP data from 213 individuals across seven local compared accuracies three...
Abstract To identify the genetic determinants of domestication and productivity Asian water buffaloes ( Bubalus bubalis ), 470 genomes domesticated river swamp along with their putative ancestors, wild arnee ) are sequenced integrated. The inherit morphology buffaloes. In contrast, most unique in morphology, but cluster levels genomic diversity Italian Indonesian decrease at opposite extremes distribution range. Purifying selection prevented accumulation harmful loss‐of‐function variants...
Mastitis caused by Staphylococcus aureus (S. aureus) infection is one of the most difficult diseases to treat in dairy cattle. Exploring biological progression S. mastitis via interaction between host, pathogen, and environment key an effective sustainable improvement animal health. Here, two strains a strain MRSA (Methicillin-resistant isolated from cows with different inflammation phenotypes were used challenge Mac-T cells investigate their effects on global transcriptome cells, then...
Embryo loss is an important factor affecting fertility in dairy production. HH2 was identified as a haplotype on chromosome 1 associated with embryonic lethality Holstein cattle. In the current study, both short- and long-read WGS performed four carriers non-carriers of to screen for variants concordance status. Sequence variation analysis revealed five putative functional protein-coding genes, including frameshift mutation (g.107172616delT) intraflagellar transport protein 80 (IFT80) gene....
Genetic introgression provides material for adaptive evolution, but also confounds our understanding of evolutionary history. This is particularly true canids, a species complex including dogs, wolves, coyotes, jackals, and other wolf-like carnivores, in which genomic analyses have revealed history admixture introgression. Among the most enigmatic canid lineages whose origin relationships remain unresolved are high-altitude wolves Tibetan Plateau, grey wolf Himalayan wolf. Here, we use newly...