A5025427609- Ferroptosis and cancer prognosis
- Cancer, Lipids, and Metabolism
- RNA modifications and cancer
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Gut microbiota and health
- Lung Cancer Treatments and Mutations
- Brain Metastases and Treatment
- Hepatitis B Virus Studies
- Neurosurgical Procedures and Complications
- Lung Cancer Research Studies
- Cancer Immunotherapy and Biomarkers
- Innovations in Medical Education
- Clostridium difficile and Clostridium perfringens research
- Cancer Research and Treatments
- Venous Thromboembolism Diagnosis and Management
- Empathy and Medical Education
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer-related gene regulation
- Problem and Project Based Learning
- Advanced Memory and Neural Computing
- S100 Proteins and Annexins
- Cancer, Hypoxia, and Metabolism
- Barrier Structure and Function Studies
- Inflammation biomarkers and pathways
University of South China
2023-2025
Sichuan University
2025
Harbin Medical University
2023-2025
Peking University
2017-2025
Southern Medical University
2023-2025
Third Affiliated Hospital of Harbin Medical University
2025
Heilongjiang University
2025
Shenzhen Maternity and Child Healthcare Hospital
2025
Baoshan College
2025
Peking University First Hospital
2025
Uncertainty exists over the size of potential beneficial effects medical treatments targeting hematoma growth in intracerebral hemorrhage (ICH). We report associations parameters on clinical outcomes pilot phase, Intensive Blood Pressure Reduction Acute Cerebral Hemorrhage Trial (INTERACT1) (ClinicalTrials.gov NCT00226096).In randomized patients with both baseline and 24-hour brain CT (n = 335), between measures absolute relative 90-day poor death dependency (modified Rankin Scale score 3-5)...
Charge trap materials that can store carriers efficiently and controllably are desired for memory applications. 2D promising highly compacted reliable mainly due to their ease of constructing atomically uniform interfaces, however, remain unexplored as being charge media. Here it is discovered semiconducting PbI
Abstract Purpose The safety of laparoscopic inguinal–hernia repair must be carefully evaluated in elderly patients. Very little is known regarding the approach patients under surgical and medical co-management (SMC). Therefore, this study patients, especially with multiple comorbidities SMC. Methods From January 2012 to December 2021, aged ≥ 65 years who underwent open or during hospitalization were consecutively enrolled. Postoperative outcomes included major minor operation-related...
Background The gut microbiota (GM) is believed to be closely associated with symptomatic carotid atherosclerosis (SCAS), yet more evidence needed substantiate the significant role of GM in SCAS. This study, based on detection bacterial DNA plaques, explores characteristics SCAS patients plaque genetic material positivity, aiming provide a reference for subsequent research. Methods We enrolled 27 healthy individuals (NHF group) and 23 (PFBS group). utilized 16S rDNA V3-V4 region gene...
Coastal mangroves are strongly nutrient-limited, but a comprehensive understanding of nutrient concentration and resorption strategies in mangrove ecosystems is lacking. In this study, we measured leaf chemical stoichiometry the species Kandelia obovata winter (January) summer (July) at six sites covering latitudinal range (19°N to 28°N) China. Leaf nitrogen (N) phosphorus (P) N:P ratio had distinct unimodal patterns along gradient both seasons. N P varied seasonally, with significantly (P <...
Introduction: Mucolipidosis II alpha/beta (ML II) is an autosomal recessive disorder with craniofacial dysmorphism and bone deformities. The variants in GNPTAB are associated ML II. Materials Methods: A female pediatric patient presented deformities, mental motor developmental abnormalities dysmorphism. We performed clinical whole-exome sequencing (WES) verified the via qPCR, gap-PCR Sanger sequencing. Results: Clinical WES identified a point variant c.1090C > T (p.R364*) copy number...
Colorectal cancer (CRC) is the third most common worldwide and second leading cause of cancer-related mortality. While early-stage CRC patients generally exhibit favorable overall survival (OS) rates, prognosis for metastatic (mCRC) remains poor, with a rate < 15%.
e16549 Background: Muscle-invasive bladder cancer (MIBC) continues to pose a significant health challenge, as conventional neoadjuvant chemotherapy (NAC) has shown limited improvements in efficacy outcomes. Recent clinical trials suggest that combining NAC with immune checkpoint blockade (NAC.NICB) may enhance therapeutic efficacy. This study aims explore the short-term and outcomes of NAC.NICB compared real-world settings for treatment MIBC. Methods: A total 100 patients MIBC who received...
Patients with non-small cell lung cancer (NSCLC) who develop brain metastases (BM) have a poor prognosis. This study aimed to construct clinical prediction model determine the overall survival (OS) of NSCLC patients BM.A total 300 BM at Yunnan Cancer Centre were retrospectively analysed. The was constructed using least absolute shrinkage and selection operator-Cox regression. bootstrap sampling method employed for internal validation. performance our compared recursive partitioning analysis...
This study investigates the efficacy and safety of bridging intravenous thrombolysis (IVT) before endovascular therapy (EVT) compared with EVT alone in patients large infarction core.
Background:Rattus norvegicus can carry and transmit various zoonotic pathogens. Some studies were conducted to investigate a few pathogens in Guangzhou, China, but no coinfections investigated or specifically mentioned. Studies on the infections influencing factors of R. along Zengjiang River Guangzhou have not been carried out. Materials Methods: In this study, was captured November 2020 September 2021 River, tested for Bartonella spp., Leptospira Orientia tsutsugamushi, Borrelia...
Air pollution significantly impacts lung cancer progression, but there is a lack of comprehensive molecular characterization clinical samples associated with air pollution. Here, we performed proteogenomic analysis adenocarcinoma (LUAD) in 169 female never-smokers from the Xuanwei area (XWLC cohort), where coal smoke primary contributor to high incidence. Genomic mutation revealed XWLC as distinct subtype LUAD separate cases smoking or endogenous factors. Mutational signature suggested that...
Postoperative cognitive dysfunction (POCD) is a common postoperative complication in older patients. Chitinase-3-like-1 protein (CHI3L1) identified as neuroinflammatory biomarker and impairs function. This study aimed to evaluate the association between serum levels of CHI3L1 POCD explore interleukin-6 (IL-6), IL-1β C-reactive (CRP) elderly after total hip arthroplasty (THA).A 76 patients undergoing THA were enrolled prospective observational study. Serum measured 1 day before surgery other...
The narrow range of distribution and special habitat Taihangia rupestris Yu et Li have rendered it endangered. absence a reliable taxonomic tool increases the difficulty identifying this species. Molecular species identification with DNA barcoding is promising for investigation conservation both endangered plant animal This approach can facilitate species-level even if only small fragment organism, flowers or fruits, at any developmental stage present. Therefore, study was undertaken to...
With the vigorous development of shipping industry, ship intelligence has become an important direction for shipbuilding and predictive maintenance health management machinery equipment can be obtained in real-time through sensors, communication, other technical means. A multi-parameter oil contaminant detection sensor is designed, which based on LC resonance sensing technology, using nested structure inner outer coils, coil set outside pipeline as reading excitation coil, induction coil....
Severe liver diseases, such as fibrosis, cirrhosis, and cancer, are mainly caused by hepatitis B virus (HBV). This study investigated the differences between gut microbiota in HBeAg-positive negative groups of patients with chronic (CHB) effect tenofovir alafenamide (TAF) on microbiota.This prospective included CHB not taking nucleoside antivirals (No-NAs group, n = 95) those TAF (TAF 60). We divided into two according to HBeAg status subjects day data collection. Phase 1 HBeAg-negative...
Abstract Background Studies have found dysbiosis of the gut microbiota in individuals infected with hepatitis B virus (HBV). Tenofovir dipivoxil (TDF) is one preferred oral antiviral drugs used for treatment chronic (CHB), but extent to which TDF able affect and inflammatory factors a patient remains largely unexplored. In this study, we collected stool samples from HBV patients prior medication CHB treated TDF. Results The were assessed 42 healthy subjects (HC group), 109 HBV-infected...