A5104668823- Aquaculture Nutrition and Growth
- Aquaculture disease management and microbiota
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Aquatic life and conservation
- MicroRNA in disease regulation
- Circular RNAs in diseases
- RNA Research and Splicing
- Physiological and biochemical adaptations
- Ferroptosis and cancer prognosis
- Environmental Toxicology and Ecotoxicology
- Cancer-related gene regulation
- RNA regulation and disease
- Hippo pathway signaling and YAP/TAZ
- Invertebrate Immune Response Mechanisms
- Biochemical Analysis and Sensing Techniques
- Ubiquitin and proteasome pathways
- Microencapsulation and Drying Processes
- Antioxidant Activity and Oxidative Stress
- Protein Degradation and Inhibitors
- Regulation of Appetite and Obesity
- Insect Utilization and Effects
- Protein Hydrolysis and Bioactive Peptides
- Neurobiology and Insect Physiology Research
- High Altitude and Hypoxia
Chinese Academy of Fishery Sciences
2015-2024
Central South University
2022-2024
Guangdong Medical College
2021-2024
Zigong First People's Hospital
2023
Beihai People's Hospital
2018-2022
Guangzhou Medical University
2017-2022
Ministry of Agriculture and Rural Affairs
2019-2022
State Key Laboratory of Respiratory Disease
2022
Affiliated Hospital of Guangdong Medical College Hospital
2021-2022
Shenzhen University Health Science Center
2022
Pyroptosis is an inflammatory form of programmed cell death implicated in inflammation and disease. Moreover, inducing pyroptosis has been appreciated as anti-cancer therapy for its ability to unleash immune responses.Utilizing the data available The Cancer Genome Atlas (TCGA), pyroptosis-related genes' (PRGs) expression, genomic aberrations, clinical significance were systematically analyzed pan-cancer. A GSVA score was obtained rate level divide cancers into pyroptosis-low pyroptosis-high...
Summary It has been reported that exercise under hypoxic conditions elevates acute growth hormone secretion after compared with normoxic conditions. This study examined the influence of resistance training moderate on muscle thickness, strength and hormonal responses. Thirteen healthy men were assigned into two groups matched for physical fitness level then randomized performed (FiO 2 = 20·9%) or 12·7%) Three sets elbow extensions unilateral arm to exhaustion at a workload 10 repetition...
Abstract Radiotherapy is one of the standard treatments for glioma patients; however, its clinical efficacy limited by radioresistance. We identified a mechanism such resistance mediated linc-RA1 (radioresistance-associated long intergenic noncoding RNA 1). Linc-RA1 was upregulated in radioresistant cells and tissue samples, compared with radiosensitive nontumor tissues. associated inferior overall survival advanced stage . promoted radioresistance vitro vivo. Mechanistically, stabilized...
Abstract Long non-coding RNAs play critical roles in the development of lung cancer by functioning as tumor suppressors or oncogenes. Changes expression LINC01279 have been associated with cell differentiation and human diseases. However, mechanism underlying activity tumorigenesis is not clear. Here, we analyzed function adenocarcinoma using clinical samples, xenografts, non-small-cell lines. We found that highly expressed may be considered a predictive factor for this cancer. Knockdown...
The aim of this study was to develop a novel long non-coding RNA (lncRNA) expression signature accurately predict early recurrence for patients with hepatocellular carcinoma (HCC) after curative resection.Using profiles downloaded from Cancer Genome Atlas database, we identified multiple lncRNAs differential between (ER) and non-early (non-ER) groups HCC. Least absolute shrinkage selection operator logistic regression models were used an lncRNA-based classifier predicting ER in the training...
Abstract Cervical cancer (CC) is one of the commonest malignant cancers among women with high morbidity and mortality. Despite encouraging advances had been found in diagnostic therapeutic strategies, effective strategy further exploration mechanism underlying CC still needed. We searched The Cancer Genome Atlas database that long noncoding RNA LINC02535 was highly expressed CC. has not studied CC, its molecular regulation remains unknown. Based on starBase database, could potentially bind...
MicroRNAs (miRs) have previously been demonstrated to be important in the tumorigenesis and progression of breast cancer. miR-372 was revealed involved various types human cancer, however its function cancer remains largely unknown. The present study that is frequently overexpressed cell lines tissues. downregulation markedly inhibited proliferation, arrested cycle G1/S phase, increased apoptosis cells. Consistently, an vivo xenograft also suppressive effects knockdown on tumor growth....
AbstractE2A transcription factors, E12 and E47, are important regulators of lymphocyte development. Notch signaling pathways have been shown to regulate E2A function by accelerating the degradation proteins through a mitogen-activated protein kinase-dependent ubiquitin-mediated pathway. To further understand mechanism underlying ubiquitination degradation, we conducted yeast two-hybrid screen identified carboxyl terminus Hsc70-interacting (CHIP) as an E47 binding protein. Here, show that...
A 56-day growth trial was conducted to determine the isoleucine requirement of juvenile Trachinotus ovatus. Six diets with different concentrations L-isoleucine (13.2, 15.7, 18.2, 20.7, 23.2 and 25.7g/kg dry diet, defined as diet Ile-1, Ile-2, Ile-3, Ile-4, Ile-5 Ile-6, respectively) were formulated contain 430g/kg crude protein fish meal, soybean peanut pre-coated crystalline amino acids. Each randomly assigned triplicate treatments 20 (initial body weight 6.36±0.03g) in seawater floating...
Abstract We report that a deletion of 19 base pairs (bp) in intron 3 the proteolipid protein (PLP/DM20) gene causes neurological disease characterized by mild developmental delay, followed progressive decline acquired motor and cognitive milestones. The clinical features are associated with delay myelination demonstrated magnetic resonance imaging studies ongoing demyelination axonal loss spectroscopy. demonstrate purine‐rich 19bp element regulates PLP‐specific splice site selection...