A5023174884- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Organic and Molecular Conductors Research
- Magnetism in coordination complexes
- Lanthanide and Transition Metal Complexes
- Histone Deacetylase Inhibitors Research
- Ferroptosis and cancer prognosis
- Antiplatelet Therapy and Cardiovascular Diseases
- Radiopharmaceutical Chemistry and Applications
- Liver Disease Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Hepatitis B Virus Studies
- Atrial Fibrillation Management and Outcomes
- Cancer Research and Treatments
- Crystallization and Solubility Studies
- ECG Monitoring and Analysis
- Circular RNAs in diseases
- Lung Cancer Research Studies
- Bone Metabolism and Diseases
- Hepatitis C virus research
- X-ray Diffraction in Crystallography
- Rough Sets and Fuzzy Logic
- Cancer, Lipids, and Metabolism
Weihai Chest Hospital
2018-2023
Yan'an University
2019
Qingdao University
2019
University of Siegen
2008
Folkwang University of the Arts
2008
To investigate the potential prognostic value of LDHA in lung adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC).Molecular, clinicopathological survival data Cancer Genome Atlas-Lung were obtained for secondary analysis.LDHA expression was significantly upregulated both LUAD LUSC compared with normal tissues. tissues had even higher Increased an independent indicator terms overall (hazard ratio: 1.547, 95% CI: 1.253-1.911; p < 0.001) recurrence-free 1.486, 1.161-1.900; = 0.002) LUAD,...
In this study, we investigated the potential prognostic value of ubiquitin-conjugating enzyme E2D1 ( UBE2D1 ) RNA expression in different histological subtypes non-small-cell lung cancer (NSCLC). A retrospective study was performed by using molecular, clinicopathological, and survival data Cancer Genome Atlas (TCGA)—Lung Cancer. Results showed that both adenocarcinoma (LUAD) (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Effects of thrombelastogram-guided (TEG-guided) clopidogrel and aspirin on major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI) were investigated. A retrospective analysis was performed 203 patients undergoing PCI interventional therapy in the Cardiovascular Medicine Weihai Central Hospital from February 2015 to September 2016. The treated with for anti-thrombus therapy. Among them, 104 who had TEG detection anticoagulant effects guiding medication...
Abstract Reaction of ligand L H 2 (4,5‐bis[carboxymethylthio]‐1,3‐dithiol‐2‐thione) with neodymium silyl‐amide (Nd[N(TMS) ] 3 ; TMS= ‐SiMe ), in a ratio 2:1, yields neodymium‐dithiolene‐carboxylato complex ( 1 ) (Nd( H) ). Similarly, reaction equivalents L′ (4,5‐bis[2′‐hydroxyethyl)thio]‐1,3‐dithiol‐2‐thione) and one equivalent allowed the isolation , ligand:metal 3:2. ATR‐IR spectrum displays broad band characteristic an OH group showing that carboxylate remains protonated. Emission under...
Objective To investigate the expression of serum ferritin in patients with breast cancer and its clinical significance. Methods Serum was determined by electrochemiluminescence 127 cases different stages, 33 benign disease 40 normal control group. Results The mean value group, stage 0 Ⅰ, stag Ⅱ, Ⅲ Ⅳ were 27.6±11.1, 30.1±25.2, 63.9±49.9, 101.2 ±67.7, 179.1±63.5, 623.3±544.1, respectively. The level significantly higher than that group gradually increased along progress...
Objective To investigate the correlation between HBV abnormal serum markers and HBV-DNA levels. Methods The 94 cases of chronic hepatitis patients were divided in 4 groups based on results serological tests. The detected by CLIA real-time fluorescence quantitative PCR, respectively. Results In group A, with coexistence HBsAg HBsAb, positive rate was 96.9% (31/32). In B, HBeAg HBeAb, 90.0% (18/20). There no statistical significance A B (x2=2.95, P>0.05). C, negative positive,...
Objective To investigate the expression of hepcidin in peripheral blood patients with breast cancer, and to explore its role pathogenesis cancer. Methods A total 58 preoperative cancer as well healthy control were recruited from Weihai central hospital; their samples collected detect expressions hepcidin, ferroportin, ferritin hemoglobin serum. Results The levels (Z=6.63, P<0.000 1) ferritinin (t=9.00, significantly higher level ferroportin was lower than controls. The not...
Objective To investigate the effect of Hepcidin on proliferation and migration breast cancer cell line MDA-MB-231 its mechanism. Methods The serum samples 58 patients schedμled for operation, who were admitted to Wendeng Central Hospital in Weihai between April 2014 May 2016, healthy controls included study. The expression was determined by enzyme-linked immunosorbent assay (ELISA) . After adding at concentrations 0, 1, 2, 4 μmol/L cells, methylthiazoletetrazolium (MTT) used examine...
Metastasis is a complex multi-step biological process involving multiple genes and biomolecules. Breast cancer clinically treated mainly by surgery, chemotherapy, radiation, which can control the growth of primary tumor, but metastatic disease still biggest clinical challenge in oncology. These methods are not very effective preventing recurrence or treating breast cancer. This article reviews several aspects metastasis, including metastasis cascade diffusion models, tumor angiogenesis, cell...