A5114626874- GABA and Rice Research
- Probiotics and Fermented Foods
- Mycotoxins in Agriculture and Food
- Food Quality and Safety Studies
- Sesquiterpenes and Asteraceae Studies
- Protein Hydrolysis and Bioactive Peptides
- Natural product bioactivities and synthesis
- Essential Oils and Antimicrobial Activity
- Bioactive Compounds and Antitumor Agents
- Light effects on plants
- Photoreceptor and optogenetics research
- Phytochemicals and Antioxidant Activities
- Adenosine and Purinergic Signaling
- Telomeres, Telomerase, and Senescence
- Agriculture, Soil, Plant Science
- Phytochemistry and Biological Activities
- Skin Protection and Aging
- bioluminescence and chemiluminescence research
- Rice Cultivation and Yield Improvement
- Allergic Rhinitis and Sensitization
- Nutrition, Health and Food Behavior
- Plant Genetic and Mutation Studies
- Endoplasmic Reticulum Stress and Disease
- Mast cells and histamine
- Ginseng Biological Effects and Applications
Ajou University
2025
Rural Development Administration
2024
Kyungpook National University
2023
Hankyong National University
2021-2023
Hallym University
2023
Sookmyung Women's University
2017-2022
Dankook University
2020
Chungnam National University
2012-2013
In this study, we investigated the anti-allergic action of mulberry fruit extract (MFE) or MFE in combination with naringinase (MFEN) IgE-activated RBL-2H3 cells, and mechanisms responsible for effects MFEN. β-hexosaminidase release assay was used to measure amount released from ELISA levels tumor necrosis factor-α (TNF-α). We found that significantly reduced (IC(50), 10.59 mg/ml) TNF-α 4.87 mg/ml). Moreover, MFEN enhanced inhibitory on 123.10 µg/ml) 65.01 µg/ml). Furthermore, had no...
본 연구는 지방함량이 낮고 건강지향적인 고품질 오디 샐러드드레싱 개발을 위해 식초대신 오미자, 점도를 높이기 생마즙을 사용하여 샐러드 드레싱을 제조하고 그 이화학적 특성 및 항산화성을 분석하였다. 드레싱에 첨가되는 재료는 샐러드베이스(플레인 요거트:마요네에즈:생크림=8:1:1):오디분쇄물:오미자청:생마즙=4:4:6:1 또는 4:4:6:3 으로 첨가하였으며, 이때 첨가된 생마는 전체 드레싱의 0,7, 18% 수준이었다. pH는 생마즙이 증가할수록 높아졌으며, 산도는 낮아졌다. 점도는 첨가하지 않은 대조군은 83.20 cP로 낮았으나, 생마즙 첨가량이 유의적으로 증가하여 7%첨가군은 113 cP, 첨가군은 125 cP 를 나타내었다(p<0.001). 유화 안정성은 첨가량과 관계없이 49-50으로 일정한 값을 나타내었다. 색도 중 명도와 황색도는 높아지는 경향을 총 페놀성 화합물 함량은 대조군이 0.087 mg/g 이었으며, 7% 첨가 드레싱은 0.101 mg/g, 0.122...
A sesquiterpene was purified from Artemisia iwayomogi methanolic extract during the course of searching anti-inflammatory principle medicinal plants. identified as armefolin inhibited production nitric oxide (NO) and attenuated inducible synthase (iNOS) protein level in lipopolysaccharide (LPS)-activated RAW 264.7 cells. Armefolin also down-regulated mRNA expressions iNOS pro-inflammatory cytokines, interleukin-1β interleukin-6 LPS-activated macrophages. Moreover, suppressed degradation...
Four sesquiterpenoids were isolated from an ethyl acetate-soluble fraction of A. princeps ethanolic extract: seco-tanapartholide B (5-epi-seco-tanapartholide A) (1), 4-epi-seco-tanapartholide A (2), 11,13-dehydrodesacetylmatricarin (3) and desacetylmatricarin (4). Compounds 1 − 3 dose-dependently inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-activated macrophages. These compounds also decreased mRNA protein expression levels inducible NO synthase cyclooxygenase-2 as well...
It is well known that oxidative stress highly associated with Parkinson's disease (PD), and biliverdin reductase A (BLVRA) to have antioxidant properties against stress. In this study, we developed a novel N-acetylgalactosamine kinase (GK2) protein transduction domain (PTD) derived from adenosine A2A fused BLVRA determine whether the GK2-BLVRA fusion could protect dopaminergic neuronal cells (SH-SY5Y) in vitro vivo using PD animal model. was transduced into various cells, including SH-SY5Y...
본 연구는 항산화능이 우수한 오디, 오미자, 생마즙(0, 7, 18%)을 사용하여 개발한 고품질 샐러드드레싱의 저장(<TEX>$5^{\circ}C$</TEX>, 4주) 기간 중 품질 특성 및 항산화능을 분석하였다. pH 산도는 생마즙의 첨가량이 증가할수록 pH는 높아지고 낮아졌으며 저장기간에 따라 다소 증가하고 감소하였으나 그 변화 폭이 적어 변화가 일어나지 않았다. 점도는 대조군은 83.2 cP로 낮았으나, 유의적으로 값이 증가하였으며(p<0.001) 모든 군에서 점도가 증가하는 경향을 나타냈다. 유화안정성은 생마즙 첨가량과 상관없이 49~50의 수준으로 나타났으며 저장기간이 경과되어도 변화를 나타내지 색도는 저장 초기 대조군에 비해 생마즙을 첨가한 실험군의 명도, 적색도, 황색도 수치가높았으며 길어질수록 감소하는 보였다. DPPH 라디칼 소거능 <TEX>$IC_{50}$</TEX> 값과 총 페놀함량을 통한 항산화성은 항산화성이 증가하였고, 따른 항산화성 저하는 관찰되지...
Deoxynivalenol (DON) is the most common mycotoxin contaminant of food or feed worldwide and causes disease in animals. Lauric acid (LA) a medium-chain fatty useful for barrier functions such as antimicrobial activity intestine monogastric However, molecular mechanisms by which lauric exerts its effects on deoxynivalenol-exposed small have not been studied. We used an intestinal porcine epithelial cell line (IPEC-J2) <italic>in vitro</italic> model to explore mechanism alleviating...
Abstract Numerous efforts have been made toward the goal of visualizing spatiotemporal dynamics single mRNA molecules, yet our capacity for precisely controlling their functions lags behind. Here, we present an optogenetic approach manipulating localization and translation specific mRNAs in live cells. Our technique combines blue light-responsive protein-protein interactions with visualization modules to robustly reversibly generate protein clusters that can trap molecules. This...