A5101961369- Plant Stress Responses and Tolerance
- MicroRNA in disease regulation
- Arsenic contamination and mitigation
- Effects of Environmental Stressors on Livestock
- Protein Degradation and Inhibitors
- Multiple Myeloma Research and Treatments
- Research in Cotton Cultivation
- Selenium in Biological Systems
- Suicide and Self-Harm Studies
- FOXO transcription factor regulation
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Plant Gene Expression Analysis
- Adipose Tissue and Metabolism
- Kruppel-like factors research
- Liver Disease Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Radioactive element chemistry and processing
- Cancer-related molecular mechanisms research
- Heat shock proteins research
- Posttraumatic Stress Disorder Research
- Barrier Structure and Function Studies
- Biochemical effects in animals
- Phytochemicals and Antioxidant Activities
- High Entropy Alloys Studies
- Spinal Dysraphism and Malformations
Hunan Agricultural University
2024
Union Hospital
2019-2024
Huazhong University of Science and Technology
2019-2024
Zhejiang A & F University
2022-2024
Sichuan University
2015-2022
University of South China
2022
Chaohu Hospital of Anhui Medical University
2021-2022
West China Hospital of Sichuan University
2015-2022
Anhui Mental Health Center
2022
Hangzhou Normal University
2022
Tissue engineered conduits have great promise for bridging peripheral nerve defects by providing physical guiding and biological cues. A flexible method integrating support cells into a conduit with desired architectures is wanted. Here, 3D-printing technology adopted to prepare bio-conduit designer structures regeneration. This consisted of cryopolymerized gelatin methacryloyl (cryoGelMA) gel cellularized adipose-derived stem (ASCs). By modeling using 3D-printed "lock key" moulds, the...
Arsenic is a significant food safety and environmental concern due to its mutagenic carcinogenic effect on living organism. Soybean (Glycine max [L.] Merrill) global staple crop grown intensively in arsenic-contaminated regions of the world (e.g., Southern Province China). Therefore, objective this study was investigate whether Se-NPs and/or ZnO-NPs could be used as an eco-friendly efficient amendment reduce arsenic uptake toxicity soybean. Ten-days-old seedling, vermiculite, were...
Cancer cells frequently use fructose as an alternative energy and carbon source, to fuel glycolysis support the synthesis of various biomacromolecules.Glut5 is only fructose-specific transporter, which lacks ability transport other carbohydrates such glucose galactose.Interplay between inflammatory factors cancer renders tissue environment a predisposing condition for development.Nevertheless, how coordinate with metabolism facilitate tumor growth remains largely elusive.Here we show that...
Accumulation of β-amyloid peptide (Aβ) in the brain plays an important role pathogenesis Alzheimer's disease (AD). Previous studies have demonstrated neuroprotective osthole against oxygen and glucose deprivation cortical neurons. However, effects on Aβ-induced neurotoxicity neural cells rarely been reported. The current study was designed to investigate protective a cell model AD insulted by exogenous Aβ25-35 potential mechanism(s). In this study,...
Objectives: The incidence of psychological and behavioral problems depression among adolescents is increasing year by year, which has become an important public health problem. Alexithymia, as susceptible factor adolescent depression, may continue to develop strengthen under the stimulation COVID-19-related stressors. However, no studies have focused on alexithymia in during pandemic China. This study aims investigate related factors pandemic. Methods: Three hundred patients were enrolled...
Calcium-Dependent Protein Kinases (CDPKs) involved in regulating downstream components of calcium signaling pathways play a role tolerance to abiotic stresses and seed development plants. However, functions only few cotton CDPKs have been clarified at present. In this study, 80 conserved Gossypium hirsutum L. were identified characterized, which was divided into four subgroups. Among them, the transcript level GhCDPK60 significantly upregulated under drought several hormone treatments. And...
Abstract Rationale and objective Clozapine (CLZ) is the most effective drug for treatment-resistant schizophrenia but associated with many side effects, including glycometabolism disorders. Immunological mechanisms may be involved in development of clozapine effects. Research relating immunomodulatory effects its early markers to clinically relevant adverse events needed reduce harmful clozapine. This study aimed investigate role proinflammatory cytokines clozapine-associated Methods We...
Internet addiction (IA) symptoms are common among adolescents and negatively impact their academic performance development. These also associated with lower quality of life (QOL) increased suicidality. This study aimed to examine the prevalence sociodemographic clinical correlates IA in major depressive disorder (MDD) association QOL.This cross-sectional was conducted three general four psychiatric hospitals Anhui Province, China, from January July 2021. Sociodemographic data were collected....
Globally, heat stress seriously threatens productivity of cattle. The objective this study was to identify novel miRNAs that regulated in feedlot Experiment conducted under and normal conditions. With profiling each cattle, our results showed the level miR-1246 significantly increased these heat-stressed cattle (P < 0.05). Furthermore, by using bioinformatics analysis luciferase reporter assays combined with qPCR western blot, we found negatively poly (C) binding protein 2 (PCBP2) cAMP...
Abstract Non-functioning pituitary adenomas (NFPAs) are the most common tumors, and some exhibit locally invasive or even clinically aggressive behavior. Circular RNAs (circRNAs) a reinvented class of non-coding that play important roles in tumor initiation progression. CircRNA microarray assays were performed 4 non-invasive NFPAs, typically differential expression circRNAs selected for validation using quantitative reverse transcription-polymerase chain reaction. The diagnostic prognostic...
Seed vigor (SV) is a crucial trait determining the quality of crop seeds. Currently, over 80% China's cotton-planting area in Xinjiang Province, where fully mechanized planting model adopted, accounting for more than 90% total fiber production. Therefore, identifying SV-related loci and genes improving cotton yield Xinjiang. In this study, three seed vigor-related traits, including germination potential, rate, index, were investigated across environments panel 355 diverse accessions based on...
Mild cognitive impairment (MCI) is a kind of non-functional decline between normal aging and dementia. With the increase individual age, quality function has become more important topic. The study gene loci in patients with MCI essential for prevention In this study, we evaluate polymorphism Chinese Han by propensity score matching (PSM) comparing them to healthy control (HC) subjects.Four hundred seventeen mild 508 people were included. two groups matched applying one-to-one PSM, tolerance...
Glioma initiating cells (GICs), also known as glioma stem cells, display the capacity to recapitulate functional diversity within tumor. Despite great progress achieved over last decades, defining key molecular regulators of GICs has represented a major obstacle in this field. In our study, data from The Cancer Genome Atlas database illustrated relationship between C-X-C motif chemokine receptor 4 (CXCR4) expression and survival patients. Mechanistically, we further indicated that CXCR4...
Abstract Activated carbon/CuO (AC/CuO) composites were prepared through a facile one-step hydrothermal method and used as bifunctional material for adsorption catalysis degradation of bisphenol A (BPA). The composite was characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), X-ray powder diffraction (XRD). obtained AC/CuO exhibited excellent catalytic performance. maximum capacity BPA on the 319.03 mg/g according to Langmuir fitting. At an...
Background: Fine particulate matter (particulate 2.5, PM2.5) is considered one of the harmful factors to neuronal functions. Apoptosis mechanisms injury induced by PM2.5. Methylcobalamine (MeCbl) has been shown have anti-apoptotic and neuroprotective effects. Objective: The current work tried explore effects that MeCbl protects mice against cognitive impairment apoptosis chronic real-time PM2.5 exposure. Methods: Twenty-four 6-week-old male C57BL/6 were exposed ambient fed with for 6 months....
Background: Radiation-induced brain injury is a serious and treatment-limiting complication of radiation therapy. Although endothelial cell dysfunction plays critical role in the development this pathogenesis, underlying molecular mechanisms remain elusive. Methods: Primary cultured rat microvascular cells (BMECs) were divided into five groups without or with exposure x-rays delivered at 5 Gy 20 Gy. For irradiated groups, continued to cultivate for 12 24 h after being irradiated. Then mRNA...
Expansins are known as cell wall loosening proteins and involved in expansion varieties of plant developmental progresses. However, little is about their biological functions alfalfa (Medicago sativa L.). In the present study, 30 MsEXP genes were identified (cultivar “zhongmu-1”) genome. Phylogenetic analysis revealed that these divided into four subfamilies, including twenty-one MsEXPAs, six MsEXPBs, one MsEXL1 two MsEXLBs. unevenly distributed on eight chromosomes. The gene structures...