- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- ECG Monitoring and Analysis
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- EEG and Brain-Computer Interfaces
- Cardiovascular Function and Risk Factors
- Healthcare Technology and Patient Monitoring
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Phonocardiography and Auscultation Techniques
- Advanced MRI Techniques and Applications
- Optical Imaging and Spectroscopy Techniques
- Muscle activation and electromyography studies
- Cardiac Health and Mental Health
- Venous Thromboembolism Diagnosis and Management
- Telemedicine and Telehealth Implementation
- Blood Pressure and Hypertension Studies
- Cardiovascular and Diving-Related Complications
- Cardiomyopathy and Myosin Studies
- Social Media in Health Education
- Neurological disorders and treatments
- Mechanical Circulatory Support Devices
University of Michigan
2016-2025
Enzo Life Sciences (United States)
2023
Michigan Medicine
2012-2023
Michigan United
2015-2023
Digital Health Cooperative Research Centre
2021-2022
Heart Rhythm Society
2020
Asklepios Klinik St. Georg
2014
Brigham and Women's Hospital
2014
Peking University
2014
Peking University Third Hospital
2014
The PhysioNet/Computing in Cardiology Challenge 2021 focused on the identification of cardiac abnormalities from electrocardiograms (ECGs) and assessed diagnostic potential reduced-lead ECGs relative to standard but less-accessible twelve-lead ECG. We sourced 131,155 recordings with clinical diagnoses seven institutions four countries, sharing 88,253 annotated publicly withholding remaining for validation testing. asked participants design working, open-source algorithms identifying...
Atrial fibrillation (AF) usually starts as paroxysmal but can evolve relentlessly to the persistent and permanent forms. However, mechanisms governing such a transition are unknown. The authors show that intracardiac serum levels of galectin (Gal)-3 greater in patients with than AF Gal-3 independently predicts atrial tachyarrhythmia recurrences after single ablation procedure. Using sheep model further demonstrate upstream therapy targeting diminishes both electrical remodeling fibrosis by...
Evaluate the performance of SANSA device to simultaneously assess obstructive sleep apnea (OSA) and cardiac arrhythmias. Participants suspected or known have OSA underwent polysomnography (PSG) while wearing SANSA. SANSA's algorithm was trained using 86 records tested on 67 evaluate training bias. evaluated against ground truth PSG scored by consensus three technologists. scoring from individual testing sites also consensus. Diagnostic standard apnea-hypopnea index (AHI) cutoffs. AHI total...
Ventricular arrhythmias have been described to originate from intramural locations. Intramural scar can be assessed by delayed-enhanced MRI, but MRIs cannot performed on every patient. The objective of this study was assess the value voltage mapping detect MRI-defined and correlate with ventricular arrhythmias.In 15 consecutive patients (3 women; age 55±16 years; ejection fraction, 49±13%) structural heart disease, detected MRI. All underwent endocardial unipolar bipolar guided registered...
The standard twelve-lead electrocardiogram (ECG) is a widely used tool for monitoring cardiac function and diagnosing disorders. development of smaller, lower-cost, easier-to-use ECG devices may improve access to care in lower-resource environments, but the diagnostic potential these unclear. This work explores issues through public competition: 2021 PhysioNet Challenge. In addition, we explore performance boosting meta-learning approach.
Abstract Aim Artificial Intelligence (AI) has the potential to transform cardiac electrophysiology (EP), particularly in arrhythmia detection, procedural optimization, and patient outcome prediction. However, a standardized approach reporting understanding AI-related research EP is lacking. This scientific statement aims develop apply checklist for enhance transparency, reproducibility understandability field. Methods An AI specific was developed with expert input from writing group voted on...
Significance How does the heart of a healthy individual cease to function within just few minutes in absence oxygen? We addressed this issue by simultaneously examining and brain animal models during asphyxiation found that asphyxia markedly stimulates neurophysiological neurochemical activities brain. Furthermore, previously unidentified corticocardiac coupling showed increased intensity as deteriorated. Blocking efferent input survival time both The results show targeting brain’s outflow...
Wearable devices may be useful for identification, quantification and characterization, management of atrial fibrillation (AF). To date, consumer wrist-worn AF detection using photoplethysmography-based algorithms perform only periodic checks when the user is stationary are US Food Drug Administration cleared prediagnostic uses without intended use clinical decision-making. There an unmet need medical-grade diagnostic that provide long-term, continuous monitoring.
Many patients who need cardiac resynchronization therapy (CRT) require chronic anticoagulation. Current guidelines recommend discontinuation of warfarin and the initiation anticoagulant "bridging" during these procedures. We evaluated safety CRT-device (CRT-D) implantation without interruption therapy.A total 123 consecutive requiring CRT-D were enrolled, 49 identified as high risk for thromboembolic events received either intravenous heparin, low molecular weight or therapy. The control...