A5052394772- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 diagnosis using AI
- Radiomics and Machine Learning in Medical Imaging
- COVID-19 and healthcare impacts
- Ultrasound in Clinical Applications
- Respiratory viral infections research
- Cancer-related molecular mechanisms research
- Cancer Cells and Metastasis
- AI in cancer detection
- Neonatal Respiratory Health Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pneumonia and Respiratory Infections
- MicroRNA in disease regulation
- Intracerebral and Subarachnoid Hemorrhage Research
- Inflammatory Bowel Disease
- Respiratory Support and Mechanisms
- Retinal and Optic Conditions
- Remote Sensing and Land Use
- Non-Invasive Vital Sign Monitoring
- E-commerce and Technology Innovations
- Gastric Cancer Management and Outcomes
- MRI in cancer diagnosis
- Hops Chemistry and Applications
- Immune cells in cancer
Helmholtz Zentrum München
2025
German Center for Lung Research
2025
Ludwig-Maximilians-Universität München
2025
Jiangnan University
2024
Wuxi Fourth People's Hospital
2024
Wuhan Red Cross Hospital
2020-2022
Shanghai Harbour Engineering Design & Research Institute
2020
Xiamen University
2014-2019
Shanghai University of Traditional Chinese Medicine
2014
The Fifth People’s Hospital of Suzhou
2010
An outbreak of a novel coronavirus disease (i.e., COVID-19) has been recorded in Wuhan, China since late December 2019, which subsequently became pandemic around the world. Although COVID-19 is an acutely treated disease, it can also be fatal with risk fatality 4.03% and highest 13.04% Algeria 12.67% Italy (as 8th April 2020). The onset serious illness may result death as consequence substantial alveolar damage progressive respiratory failure. laboratory testing, e.g., using reverse...
Phytogenic compounds with anti-oxidant and anti-inflammatory properties, such as ginsenoside metabolite compound K (CK) or berberine (BBR), are currently discussed promising complementary agents in the prevention treatment of cancer inflammation. The latest study showed that Rb1 its metabolites could inhibit TNBS-induced colitis injury. However, functional mechanisms anti-inflammation effects ginsenoside, particularly CK still not clear. Here, using dextran sulfate sodium (DSS)-induced mice,...
// Weiwei Wang 1, * , Wei Zhong Jiahui Yuan 1 Congcong Yan Shaoping Hu Yinping Tong Yubin Mao 2 Tianhui Bing Zhang Gang Song Cancer Research Center, Medical College of Xiamen University, 361102, China Department Basic Medicine, These authors have contributed equally to this work Correspondence to: Song, e-mail: gangsongsd@xmu.edu.cn Keywords: cholangiocarcinoma, MSCs, metastasis, chemoresistance, β-catenin Received: April 17, 2015 Accepted: September 05, Published: October 14, ABSTRACT...
Our previous work has demonstrated that mesenchymal stem cells (MSCs) could induce metastatic growth of the inflammation-related cholangiocarcinoma (CCA). However, functional mechanism MSCs on CCA progression in early inflammatory microenvironment remained undetermined. Here, we showed TNF-α and IFN-γ-induced stimulated expression TNF-α, CCL5, IL-6, IDO, activated NF-κB signaling with p65 nuclear translocation cells. cell lines QBC939 Mz-chA-1 exposed to conditioned medium after being by...
With the rapid spread of COVID-19 worldwide, early detection and efficient isolation suspected patients are especially important to prevent transmission. Although nucleic acid testing SARS-CoV-2 is still gold standard for diagnosis, there well-recognized early-detection problems including time-consuming in diagnosis process, noticeable false-negative rate stage lacking kits some areas. Therefore, effective rational applications imaging technologies critical aiding screen helping patients....
Abstract Lung fibrosis development utilizes alveolar macrophages, with mechanisms that are incompletely understood. Here, we fate map connective tissue during mouse lung and observe disassembly transfer of macromolecules from pleuro-alveolar junctions (PAJs) into deep tissue, to activate fibroblasts fibrosis. Disassembly PAJ occurs by activating cysteine-type proteolysis on pleural mesothelium. The niche the cascade is active in patient biopsies, persists chronic models, wanes down acute...
COVID-19 is a new pneumonia. It has been hypothesized that tobacco smoking history may increase severity of this disease in the patients once infected by underlying coronavirus SARS-CoV-2 because and both cause lung damage. However, hypothesis not tested.
Facing the novel coronavirus disease 2019 (COVID-19), most vulnerable individuals are seniors, especially those with comorbidities. More attention needs to been paid COVID-19 patients Alzheimer's (AD), which is top age-related neurodegenerative disease.Since it unclear whether AD prone infection and progression severe stages, we report for first time a retrospective analysis of clinical characteristics pneumonia.We conducted cohort study data 19 pneumonia, compared 23 non-AD admitted at same...
To investigate the epidemiological and clinical characteristics of children with
Background: The 2019 novel coronavirus-infected disease (COVID-19) breakout in Wuhan of China has caused growing concerns about the consequences. Here we report worst consequence, death cases with COVID-19, aiming to find out main causes and risk factors. Methods: Retrospective, single-center case series two groups, 65 deceased patients (i.e., those not survive, leading cases) 96 surviving patients, all were confirmed COVID-19 at Red Cross Hospital from January 21st February 14th, 2020....
Objectives: Both coronavirus disease 2019 (COVID-19) pneumonia and influenza A (H1N1) are highly contagious diseases. We aimed to characterize initial computed tomography (CT) clinical features develop a model for differentiating COVID-19 from H1N1 pneumonia. Methods: In total, we enrolled 291 patients with January 20 February 13, 2020, 97 May 24, 2009, 29, 2010 two hospitals. Patients were randomly grouped into primary cohort validation using seven-to-three ratio, their clinicoradiologic...
Elderly populations with underlying chronic diseases are more vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and have higher mortality. Parkinson's disease (PD) is a neurodegenerative that occurs often in elderly people. Currently, little known about whether patients PD susceptible novel 2019 (COVID-19) the treatment of would affect management COVID-19 or vice versa. Here, we report case patient pneumonia Wuhan, China. After diagnosis COVID-19, this had...
Humulus scandens, rich in flavonoids, is a traditional Chinese medicine. It widely used China to treat tuberculosis, dysentery and chronic colitis. In this study, the major active faction of scandens (H.S) was prepared. Then, its immunosuppressive effects underlying mechanisms on T cell activation were investigated vitro vivo. Results showed that H.S significantly inhibited proliferation splenocytes induced by concanavalin A, lipopolysaccharides, mixed-lymphocyte reaction vitro....
An outbreak of a novel coronavirus disease (i.e., COVID-19) has been recorded in Wuhan, China since late December 2019, which subsequently became pandemic around the world. Although COVID-19 is an acutely treated disease, it can also be fatal with risk fatality 4.03% and highest 13.04% Algeria 12.67% Italy (as 8th April 2020). The onset serious illness may result death as consequence substantial alveolar damage progressive respiratory failure. laboratory testing, e.g., using reverse...
<h3>Background</h3> CCR8-expressing CD4 and Foxp3 positive Treg (CCR8+ Treg) has been demonstrated to be a major driver for immunosuppression in solid tumors1 <1> Superscript. Clinical studies have shown that CCR8 is selectively up-regulated by tumor resident Tregs several types including clear cell renal carcinoma (ccRCC)2 <2> Superscript breast cancer3 <3> In these types, exhibit strong expression on while it rarely observed peripheral blood mononuclear cells (PBMCs)....