A5100423395- Cancer-related molecular mechanisms research
- Perovskite Materials and Applications
- Food Quality and Safety Studies
- Mycobacterium research and diagnosis
- RNA modifications and cancer
- Endoplasmic Reticulum Stress and Disease
- Noise Effects and Management
- Skin and Cellular Biology Research
- Chalcogenide Semiconductor Thin Films
- Solid-state spectroscopy and crystallography
- Biochemical Analysis and Sensing Techniques
- Probiotics and Fermented Foods
- Cellular Mechanics and Interactions
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Fiscal Policy and Economic Growth
- Music Therapy and Health
- Cancer Genomics and Diagnostics
- Health, psychology, and well-being
- Pain Management and Treatment
- Signaling Pathways in Disease
- Synthetic Aperture Radar (SAR) Applications and Techniques
- Advanced Biosensing Techniques and Applications
- Workplace Health and Well-being
- Crystal Structures and Properties
Southern Medical University
2022-2025
Peking University
2025
State Key Laboratory of Microbial Technology
2025
Peking University Third Hospital
2025
Shandong University
2025
Zhejiang University
2024
Beijing University of Chinese Medicine
2024
Southwest University of Science and Technology
2024
RELX Group (United States)
2023
Faculty of 1000 (United States)
2023
Individuals with inactive pulmonary tuberculosis (PTB) lesions were found to be high-risk populations for active PTB development. This retrospective study evaluated the association between different types of and development aiming provide epidemiological evidence developing precise intervention strategies. Based on a population-based case-finding project conducted elderly, total 154 028 subjects who had participated in 2020 baseline survey was included current analysis. During 2-year...
Background Cardiovascular disease (CVD) remains a major health concern globally, contributing to considerable burden. However, few studies have considered long-term cumulative blood pressure (cBP) exposure in middle-aged and older population China. The aim of this study was investigate whether cBP associated with subsequent cardiovascular outcomes among participants without CVD at baseline Chinese over 45 years old.
To identify the core supportive care needs of ostomy patients across postoperative period using network analysis to inform targeted interventions. This cross-sectional study was conducted according STROBE guidelines. included 588 from three tertiary Grade-A hospitals in China between December 2023 and March 2024. Supportive were assessed an adapted version short form Care Needs Survey. Data analysed descriptive statistics, one-way ANOVA explore interconnections centrality symptoms four...
Members of Eubacteriaceae are involved in host health and diseases. Two Gram-stain-positive, strictly anaerobic, non-motile, non-spore-forming, rod-shaped bacterial strains, HA2171T HA2172T, were isolated from the feces Chinese healthy donors. Based on 16S rRNA gene sequences, HA2172T belonged to family Eubacteriaceae. Physiological biochemical characterizations indicated that neutrophilic, mesophilic, tolerant low-concentration NaCl. The major cellular fatty acids (>10.0%) C16:0, C14:0,...
Abstract Bromodomain‐containing protein 7 (BRD7) is a tumour suppressor that known to regulate many pathological processes including cell growth, apoptosis and cycle. Endoplasmic reticulum (ER) stress‐induced plays key role in diabetic cardiomyopathy (DCM). However, the molecular mechanism of hyperglycaemia‐induced myocardial still unclear. We intended determine BRD7 high glucose (HG)‐induced cardiomyocytes. In vivo , we established type 1 rat model by injecting high‐dose streptozotocin...
Abstract Expansion microscopy (ExM) increases the effective resolving power of any microscope by expanding sample with swellable hydrogel. Since its invention, ExM has been successfully applied to a wide range cell, tissue and animal samples. Still, fluorescence signal loss during polymerization digestion limits molecular-scale imaging using ExM. Here we report development label-retention (LR-ExM) set trifunctional anchors that not only prevent but also enable high-efficiency labeling SNAP...
To assess the association of pulmonary tuberculosis (PTB) recurrence with fine particulate matter (PM2.5) and residential greenness using a population-based retrospective study design. All incident PTB patients, registered in Tuberculosis Information Management System (TBIMS) from 2015 to 2019 Quzhou City, China, were included. The data on PM2.5 exposure was extracted China High Air Pollutants dataset level estimated Normalized Difference Vegetation Index (NDVI) values around patient's...
Previous literature on social cohesion has emphasized the role of daily activities but overlooked their interrelated nature resulting from space-time constraints. Moreover, gendered constraints found in recent studies add complexity to mechanism. This research broadens scope by adopting a activity perspective. Utilizing data an diary survey conducted 2021 Fuzhou, China, we explore gender differences impact housework activity, employment and neighborly cohesion, considering Employing...
The Daguangbao landslide (DGBL), triggered by the 2008 Wenchuan earthquake, is a rare instance of super-giant landslides globally. post-earthquake evolution DGBL has garnered significant attention in recent years; however, its deformation patterns remain poorly characterized owing to complex local topography. In this study, we present first observations surface dynamics integrating satellite- and ground-based InSAR data complemented kinematic interpretation using LiDAR-derived Digital...
Although stroke is a major human neurological disease, there paucity of effective neuroprotectants that can improve its treatment. Casticin natural monomer drug with many biological effects such as anti-inflammatory and anti-tumor actions. However, it not clear whether has neuroprotective effect in ischemic stroke. In this study, the casticin rat middle cerebral artery occlusion (MCAO) model was investigated. Results showed reduced volume infarction, mNSS scores, swimming distance, time to...
The effect of serum L-carnitine (LC) concentrations on cancer risk remains unclear. This study aims to explore the association between LC and incident cancer.This is a case-control study, including 574 patients with controls matched in 1:1 ratio by age, sex, residence, nested within China H-Type Hypertension Registry Study (CHHRS). Conditional logistic regression analysis was used assess risk.When assessed as quartiles, compared low (Q1), highest quartile (Q4) had 33% (OR = 0.67, 95% CI:...
Pulmonary tuberculosis (PTB) infection is a chronic inflammatory response caused by Mycobacterium (Mtb). The purpose of this study was to confirm the value long noncoding RNA NORAD (noncoding activated DNA damage) in diagnosis PTB and explore its mechanism Mtb-infected macrophages. serum levels were estimated qRT-PCR 90 patients with 85 healthy individuals. Receiver operating characteristic curves plotted assess diagnostic PTB. Human murine macrophages infected Mtb strain H37Rv. CCK-8 (a...
The study investigated the clinical diagnostic value of long non-coding RNA (LncRNA) small nucleolar host gene 16 (SNHG16) and explored its underlying molecular mechanism through Mycobacterium tuberculosis (M. tuberculosiinfection macrophages.RT-qPCR analysis serum SNHG16 levels 66 healthy individuals, 67 latent TB (LTB) patients, active (ATB) patients. receiver-operating characteristic (ROC) curve to detect in In vitro, M. tuberculosis-infected macrophages, CCK-8 ELISA cell proliferation...
Abstract Objective The objective of this study was to perform noninvasive analysis skin proteins in a healthy Chinese population using label‐free nanoflow liquid chromatography‐mass spectrometry ( nLC ‐ MS ). Materials and Methods Five consecutive tape strippings were obtained from the volar forearm subjects. Proteins extracted, trypsin‐digested peptides analyzed by nanochromatography instrument coupled an Orbitrap Fusion Tribrid mass spectrometer. Data‐dependent acquisition allowed protein...