A5101743390- Thyroid Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Hypoxia, and Metabolism
- Immune Response and Inflammation
- Cancer Cells and Metastasis
- Human Pose and Action Recognition
- 3D Shape Modeling and Analysis
- T-cell and B-cell Immunology
- Lung Cancer Research Studies
- Head and Neck Cancer Studies
- Face recognition and analysis
- Pancreatic function and diabetes
- Biosimilars and Bioanalytical Methods
- Cancer-related Molecular Pathways
- Photodynamic Therapy Research Studies
- Inflammasome and immune disorders
- Intensive Care Unit Cognitive Disorders
- Nanoplatforms for cancer theranostics
- Cytokine Signaling Pathways and Interactions
- Salivary Gland Tumors Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- RNA Research and Splicing
- CRISPR and Genetic Engineering
- Oral health in cancer treatment
- Fatty Acid Research and Health
Zhejiang University
2012-2025
Kunming Medical University
2025
First Affiliated Hospital of Kunming Medical University
2025
Children's Hospital of Fudan University
2025
First Affiliated Hospital of Xi'an Jiaotong University
2024
Chinese PLA General Hospital
2023-2024
West China Hospital of Sichuan University
2023
Sichuan University
2023
Qinghai Provincial Peoples Hospital
2023
Nankai University
2023
Patients with triple-negative breast cancers (TNBC) are at a high risk for recurrent or metastatic disease, and the molecular mechanisms associated this unclear. Proteoglycan serglycin (SRGN) proteins involved in tumor metastasis, but their role TNBC has not yet been elucidated. This study investigates SRGN gene expression how it regulates TGFβ2 downstream signaling of cells tissues. Our results show that mRNA protein levels were significantly higher cell lines tissues than non-TNBC We...
The most prevalent types of lymphomas are B cell (BCL). Newer therapies for BCL have improved the prognosis many patients. However, approximately 30% with aggressive either remain refractory or ultimately relapse. These patients urgently need other options. This study shows how calcium/calmodulin-dependent protein kinase II delta (CAMKIIδ) is pivotal development. In cells, ablation CAMKIIδ inhibits both lipolysis from lipid droplets and oxidative phosphorylation (OXPHOS). With blocked,...
Automatic pain assessment for non-communicative children is in high demand. However, the availability of related training datasets remains limited. This study focuses on creating a large-scale dataset facial expressions specifically Chinese critically ill and evaluating its utility using deep learning models. Data were gathered from two intensive care units at Children's Hospital Fudan University. The dataset, named expression (PFECIC), includes 119 videos 6951 images collected 53 between...
Objectives: Coarse calcifications are prone to cause echo attenuation during ultrasonography (US) and hence affect the classification of benign malignant nodules. This study aimed investigate diagnostic role computed tomography (CT) for differentiating American College Radiology (ACR) Thyroid Imaging Reporting Data System (TI-RADS) 4−5 nodules with coarse calcifications. Methods: CT data 216 ACR TI-RADS confirmed by surgery pathology in 207 patients were analyzed retrospectively. Halo sign,...
Dysfunctions in nucleic acid-sensing Toll-like receptors (TLRs) disrupt acid tolerance, leading to systemic lupus erythematosus (SLE). Here, we report a novel homozygous gain-of-function p.R95L mutation the TLR chaperone protein UNC93B1 an SLE patient. Bulk and single-cell transcriptional analysis of patient's peripheral blood mononuclear cells (PBMCs) revealed significantly elevated inflammation T myeloid due enhanced dendritic function. The R95L leads hyperactivation TLR7/8, but not...
To analyze the preventive and therapeutic effects of comprehensive nursing interventions on chemotherapy-induced oral mucositis in pediatric patients with hematologic malignancies.
Objective To discuss the predictive value of multiple ultrasonic features combination in diagnosis thyroid papillary carcinoma (PTC) more than 1.0 cm diameter. Methods The 258 PTC nodules from 251 patients and 207 nodular goiter (NG) 190 First People′s Hospital Hangzhou were retrospectively analyzed. All confirmed by pathological examination after surgery. The included shape nodules, internal echo, anteroposterior/transverse diameter ratio (A/T), microcalcification. χ2 test was used...
<sec> <title>BACKGROUND</title> For critically ill children who cannot communicate and express themselves sufficiently, facial expressions are important indicators of their pain levels. Dataset training testing quality is a crucial factor affecting the performance expression analysis algorithms. Establishing high-quality standardized dataset requires in-depth research. </sec> <title>OBJECTIVE</title> This study aims to propose standard for constructing expression-based assessment by...
Photodynamic therapy (PDT) has limited effects in treating metastatic breast cancer. Immune checkpoints can deplete the function of immune cells; however, expression after PDT is unclear. This study investigates whether efficacy due to upregulated and tries combine checkpoint inhibitor observe efficacy. A cancer model was treated by mediated hematoporphyrin derivatives (HpD-PDT). The anti-tumor effect HpD-PDT observed, as well CD4[Formula: see text]T, CD8[Formula: text]T calreticulin (CRT)...