A5059343029- Pluripotent Stem Cells Research
- Tissue Engineering and Regenerative Medicine
- Cytokine Signaling Pathways and Interactions
- Natural Compounds in Disease Treatment
- Cancer Immunotherapy and Biomarkers
- Congenital heart defects research
- Adipose Tissue and Metabolism
- Cancer-related molecular mechanisms research
- Rheumatoid Arthritis Research and Therapies
- Microtubule and mitosis dynamics
- Lanthanide and Transition Metal Complexes
- Lung Cancer Research Studies
- Medicinal Plant Pharmacodynamics Research
- Diet and metabolism studies
- Lung Cancer Treatments and Mutations
- Gut microbiota and health
- Cardiovascular Function and Risk Factors
- Medical Imaging Techniques and Applications
- CRISPR and Genetic Engineering
- Electrospun Nanofibers in Biomedical Applications
- Immune Cell Function and Interaction
- Medicinal Plants and Bioactive Compounds
- Circular RNAs in diseases
- Intraperitoneal and Appendiceal Malignancies
- Electrochemical sensors and biosensors
Anhui University of Traditional Chinese Medicine
2012-2025
Jilin Province Tumor Hospital
2023-2025
Nantong Tumor Hospital
2025
Peking University
2024
State Key Laboratory of Turbulence and Complex Systems
2024
Dalian Medical University
2024
Chongqing Medical University
2024
Second Affiliated Hospital of Chongqing Medical University
2024
Institute of Biomedical Sciences, Academia Sinica
2006-2023
Academia Sinica
2006-2022
The gut microbiome and its metabolites are increasingly implicated in several cardiovascular diseases, but their role human myocardial infarction (MI) injury responses have yet to be established. To address this, we examined stool samples from 77 ST-elevation MI (STEMI) patients using 16 S V3-V4 next-generation sequencing, metagenomics machine learning. Our analysis identified an enriched population of butyrate-producing bacteria. These findings were then validated a controlled...
A systematic survey of expression profiles glycosphingolipids (GSLs) in two hESC lines and their differentiated embryoid body (EB) outgrowth with three germ layers was carried out using immunofluorescence, flow cytometry, MALDI-MS MS/MS analyses. In addition to the well-known hESC-specific markers stage-specific embryonic antigen 3 (SSEA-3) SSEA-4, we identified several globosides lacto-series GSLs, previously unrevealed hESCs, including Gb 4 Cer, Lc fucosyl Globo H, disialyl 5 Cer. During...
Cardiac regeneration after injury is limited by the low proliferative capacity of adult mammalian cardiomyocytes (CMs). However, certain animals readily regenerate lost myocardium through a process involving dedifferentiation, which unlocks their capacities.
Summary Aim Nerve growth factor ( NGF ) regulates neuronal survival and differentiation by activating extracellular signal‐regulated‐kinases ERK 1/2 phosphoinositide‐3‐kinase PI 3K)/Akt pathways in two distinct processes: latency process neurite extension process. This study was designed to investigate whether botanical drug C‐glucosylated isoflavone puerarin coordinates with regulate neuritogenesis via 3K/Akt Methods We investigated the neuroprotective neurotrophic activities of MPTP...
Glycosphingolipids (GSLs) are ubiquitous components of cell membranes that can act as mediators adhesion and signal transduction possibly be used type-specific markers. Our previous study indicated there was a striking switch in the core structures GSLs during differentiation human embryonic stem cells (hESCs) into embryoid body (EB), suggesting close association with differentiation. In this study, to further clarify if alterations GSL patterns correlated lineage-specific hESCs, we analyzed...
Research Article23 December 2016Open Access Transparent process Reprogramming-derived gene cocktail increases cardiomyocyte proliferation for heart regeneration Yuan-Yuan Cheng Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan Biomedical Academia Sinica, Search more papers by this author Yu-Ting Yan David J Lundy Annie HA Lo Yu-Ping Wang Shu-Chian Ruan Po-Ju Lin Patrick CH Hsieh Corresponding Author [email protected] orcid.org/0000-0002-8910-3596 Department...
Abstract Biofuel cells (BFCs) use enzymes and microbial to produce energy from bioavailable substrates treat various wastewaters, cathodic oxygen reduction is a key factor governing the efficiency of BFCs. In this study, we demonstrated that green alga, Chlamydomonas reinhardtii , could directly mediate reduction. Cyclic voltammogram analysis revealed C. biofilm formed on solid electrode was responsible for without dosing electron mediator. Furthermore, 4‐electron pathway found in...
Background Prostaglandin E2 has long been known to be an immune modulator. It is released after tissue injury and plays a role in modulating macrophage activities, which are essential for regeneration. However, the involvement of prostaglandin receptor 2 ( EP 2)-dependent regulation macrophages postischemic heart unclear. This study aims evaluate damaged heart. Methods Results The effect was evaluated using 2-deficient transgenic mice. We demonstrated that cardiac function worse myocardial...
Tripterygium is a Chinese herb with immunosuppressive effects and an established history of use in the treatment rheumatoid arthritis. Previous studies demonstrated that tripterygium glycosides (TPG) alleviated Freund's complete adjuvant (FCA)-induced Simultaneously, it has also been observed to impact arthritis (AA) associated lung injury. In this study, we have investigated whether traditional medicine could attenuate injury induced by AA observing TPG on degree swelling, index (AI), (LI),...
Rationale: Gut microbiota plays a crucial role in cancer development and treatment.Studies show that although the gut is able to promote tumor growth, its presence also improves efficacy of treatment such as immunotherapy.To date, understanding potential impact on other modalities nanomedicine still limited.In this study, we aimed establish relationship between nanomedicine, which can potentially open new path combines modulation along with nanotherapeutics.Methods: Mice bearing 4T1...
Objective Given the intricate challenges and potential complications associated with periacetabular osteotomy (PAO) for developmental dysplasia of hip (DDH). Our study aimed to compare clinical imaging benefits drawbacks two surgical approaches, modified Stoppa combined iliac spine approach Smith–Peterson approach, treating PAO provide guidance selecting approaches. Methods A retrospective analysis 56 patients 62 DDHs was conducted from June 2018 January 2022. The experimental group...