A5042936826- Bariatric Surgery and Outcomes
- Body Contouring and Surgery
- Diet and metabolism studies
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Obesity and Health Practices
- Minimally Invasive Surgical Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Gallbladder and Bile Duct Disorders
- Colorectal Cancer Surgical Treatments
- Pelvic floor disorders treatments
- Eating Disorders and Behaviors
- Hernia repair and management
- Gastroesophageal reflux and treatments
- Cardiovascular Disease and Adiposity
- Abdominal Surgery and Complications
- Thyroid Cancer Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Gastrointestinal Tumor Research and Treatment
- Celiac Disease Research and Management
- Intestinal and Peritoneal Adhesions
- Anorectal Disease Treatments and Outcomes
- Nutrition and Health in Aging
- Gastrointestinal disorders and treatments
University of Rome Tor Vergata
2016-2025
Ospedale San Carlo
2022-2025
Maria Cecilia Hospital
2023-2025
Winterthur Museum Garden and Library
2023
Carlo Forlanini Hospital
2023
Policlinico Tor Vergata
2007-2022
Azienda Sanitaria Unità Locale di Reggio Emilia
2021
Istituti di Ricovero e Cura a Carattere Scientifico
2021
Sapienza University of Rome
2011
Magna Graecia University
2011
In Brief Objective: To evaluate the early effect of Roux-en-Y (RYGB) gastric bypass on hormones involved in body weight regulation and glucose metabolism. Significant Background Data: The RYGB is an effective bariatric procedure for which mechanism action has not been elucidated yet. Reports hormonal changes after suggest a possible endocrine operation; however, it unknown whether these are cause or rather surgically induced loss. We speculated that if involves effect, then should occur...
Abstract Background The gut microbiome and iron status are known to play a role in the pathophysiology of non-alcoholic fatty liver disease (NAFLD), although their complex interaction remains unclear. Results Here, we applied an integrative systems medicine approach (faecal metagenomics, plasma urine metabolomics, hepatic transcriptomics) 2 well-characterised human cohorts subjects with obesity (discovery n = 49 validation 628) independent cohort formed by both individuals without ( 130),...
The unresolved chronic inflammation of white adipose tissue (WAT) in obesity leads to interstitial deposition fibrogenic proteins as reparative process. contribution omental (oWAT) fibrosis obesity-related complications remains controversial. aim our study was investigate whether oWAT may be related insulin resistance severely obese population.Forty subjects were studied by glucose clamp before undergoing bariatric surgery and thus stratified according severity (M-value). From the first...
Obesity represents one of the most complex public health challenges and has recently reached epidemic proportions. is also considered to be primarily responsible for rising prevalence metabolic syndrome, defined as coexistence in same individual several risk factors atherosclerosis, including dyslipidemia, hypertension hyperglycemia, well cancer. Additionally, presence three five (abdominal obesity, low high-density lipoprotein cholesterol, high triglycerides, fasting glucose blood pressure)...
Efficacy and safety of OAGB/MGB (one anastomosis/mini gastric bypass) have been well documented both as primary revisional procedures. However, even after OAGB/MGB, surgery is unavoidable in patients with surgical complications or insufficient weight loss.A questionnaire asking for the total number demographics OAGB/MGBs performed between January 2006 July 2020 was e-mailed to all S.I.C. OB centres excellence (annual caseload > 100; 5-year follow-up 50%). Each bariatric centre asked provide...
Objective— Tissue inhibitor of metalloproteinase 3 (TIMP3) is a stromal protein that inhibits the activity proteases and receptors. TIMP3 downregulated in metabolic inflammatory disorders, such as type 2 diabetes mellitus atherosclerosis, particularly regions enriched with monocyte/macrophage cells. To investigate role we generated new mouse model which Timp3 was overexpressed atherosclerotic plaque via macrophage-specific promoter (MacT3). We elucidated any potential antiatherosclerotic...
The tissue inhibitor of metalloproteinase (TIMP)3, a stromal protein that restrains the activity proteases and receptors, is reduced in inflammatory metabolic disorders such as type 2 diabetes mellitus (T2DM) atherosclerosis. We overexpressed Timp3 mouse macrophages (MacT3) to analyze its potential antidiabetic antiatherosclerotic effects. Transgenic mice with myeloid cells targeting overexpression TIMP3 were generated fed high-fat diet for 20 weeks. Physical phenotypes determined....
Purpose: The objective of this retrospective study was to observe whether more frequent long-term medical follow-up visits than what occurs with the current typical schedule might prevent weight regain and nutritional deficiencies, improve resolution comorbidities in bariatric patients. Materials Methods: Clinical reports were examined patients (n=71, 16 males, age 42±11.6 years, body mass index [BMI] 48.6±7.9 kg/m2) who had a minimum 36 months post-surgery follow-up. All after surgery at 1,...
For bariatric surgery candidates body image dissatisfaction (BID) may influence both psychological well-being and motivation to obtain surgery. This study aims examine possible psychiatric predictors of BID. In particular, we explored the burden new associated factors such as early trauma attachment style (AS), which have not been assessed in previous literature.In this study, 536 patients with extreme obesity (mean Body Mass Index, BMI=43 kg/m2, SD=6.62) undergoing presurgical evaluations...