A5054062335- Neonatal Respiratory Health Research
- Fatty Acid Research and Health
- Cholesterol and Lipid Metabolism
- Congenital Diaphragmatic Hernia Studies
- Educational Practices and Policies
- Biomedical and Chemical Research
- Dutch Social and Cultural Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Retinopathy of Prematurity Studies
- Child and Adolescent Health
- Pregnancy and preeclampsia studies
- Diet and metabolism studies
- Infant Development and Preterm Care
- Renal function and acid-base balance
- Health and Medical Studies
- Neuroscience of respiration and sleep
- Neonatal and Maternal Infections
- Antioxidant Activity and Oxidative Stress
- Streptococcal Infections and Treatments
- Diet, Metabolism, and Disease
- Scientific and Historical Analyses
- Tuberous Sclerosis Complex Research
- Cardiovascular Conditions and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Childhood Cancer Survivors' Quality of Life
München Klinik Harlaching
2020-2025
München Klinik Schwabing
2020-2025
München Klinik
2023-2025
Technical University of Munich
2020-2021
Post Apotheke
2018
Klinikum Magdeburg
2016
University of Münster
2016
University Medical Center Freiburg
2004-2015
University of Freiburg
1996-2015
Zentrum für Kinderheilkunde
2003-2013
Importance The inclusion of less invasive surfactant administration (LISA) in the care preterm infants has been found to be beneficial for respiratory outcomes. Recently, OPTIMIST trial higher mortality rates subgroup born at 25 26 weeks’ gestational age (GA) who received treatment while spontaneously breathing. Objective To analyze outcomes among LISA-exposed, highly vulnerable babies than 27 GA within large-scale observational cohort German Neonatal Network. Design, Setting, and...
<h3>Aim:</h3> To study prospectively the plasma levels of vascular endothelial growth factor (VEGF-A), its soluble receptors sVEGFR-1, sVEGFR-2 and Tie2 in premature infants. identify their changes related to onset retinopathy prematurity (ROP). <h3>Methods:</h3> Blood samples 63 preterm infants born at a postmenstrual age (PMA) 23–32 weeks were obtained between 5 days 15 after birth. 42 had no ROP, two stage 1, nine 2 10 3. Of these, four treated with retinal photocoagulation. VEGF-A,...
Mutations in TPM3, encoding Tpm3.12, cause a clinically and histopathologically diverse group of myopathies characterized by muscle weakness. We report two patients with novel de novo Tpm3.12 single glutamic acid deletions at positions ΔE218 ΔE224, resulting significant hypercontractile phenotype congenital stiffness, rather than weakness, respiratory failure one patient.The effect the on contractile properties dissected patient myofibers was measured. used quantitative vitro motility assay...
The effective utilization of staff resources is decisive importance for the adequate, appropriate, and economical delivery hospital services. goal this study was to determine distribution working time among doctors in a German university hospital-in particular, terms type activities day.The determined from 14-day samples taken seven clinical departments Medical Center-University Freiburg. In each sample, being carried out at multiple, randomly chosen times were recorded.A total 250...
Group B Streptococcus (GBS) is a common intestinal colonizer during the neonatal period, but also may cause late-onset sepsis or meningitis in up to 0.5% of otherwise healthy colonized infants after day 3 life. Transmission routes and risk factors this form invasive GBS disease (iGBS) are not fully understood. Cases iGBS with recurrence (n=25) those occurring parallel twins/triplets (n=32) from UK Ireland (national surveillance study 2014/15) Germany Switzerland (retrospective case...
Importance Retinopathy of prematurity (ROP) is a major morbidity preterm infants causing visual impairment, including blindness, for which timely treatment vital and prevention key. Increasing evidence suggests that exposure to neonatal sepsis contributes ROP development. Objective To investigate the association between in 2 large-scale cohorts born at less than 29 weeks’ gestation. Design, Setting, Participants This retrospective cohort study was conducted using data from German Neonatal...
Abstract Background The Covid-19 pandemic restrictions severely impacted parents’ and children’s mental physical health. Families with pre-existing stress factors may have been particularly affected. Parental following premature birth is well acknowledged. addition of the to stressors related constitute an especially high-risk factor for family thereby neuropsychological development. Accessibility special preterm follow-up care programs important development faced additional relevance in...
<title>Abstract</title> Objective To assess whether neonates with critical congenital heart defects (cCHD) can be safely delivered and stabilized at a Level-III perinatal center lacking dedicated paediatric cardiology unit. Methods Retrospective single-center cohort study (2018–2022) tertiary cardiologists on staff but no Inclusion of all prenatally or postnatally diagnosed cCHD the followed until transfer discharge. Main outcome measures Integrated prenatal neonatal care prior to for...
Prolonged testing of marine fish oil (FO) as a dietary supplement is necessary because widespread claims that it antiatherogenic. The basis for such inadequate atherogenesis chronic and may not respond to short-term changes induced by treatments. A proven (vervet) model atherosclerosis promoted an atherogenic diet (AD) was used test supplementation with Atlantic pilchard FO 20 months in 47 omnivorous nonhuman primates. Responses were controlled against known favorable effects changing from...
Purpose.: To prospectively study plasma levels of soluble E-selectin (sE-selectin) in premature infants and to identify their relationship retinopathy prematurity (ROP) on the background known clinical risk factors. Methods.: Eighty-five sE-selectin samples from 42 preterm born at 23 32 weeks gestational age (GA) were analyzed. Twenty-two did not have ROP, eight had stage I, seven II, five III. Infants having no ROP or I designated as no-ROP group, with II III formed group. Results.: In...
Palm oil (PO) contains ~43% of palmitic acid. It is the most abundant saturated fatty acid in diet and it generally considered primary cholesterol (C)-raising However, effect on plasma appears to depend content diet. The aim this study was determine PO with either a high-fat, high-C or moderate-fat, moderate-C lipoprotein C low-density (LDL) composition. Fifty adult, male vervet monkeys were randomly assigned high-fat group (HFD: 35%E fat, ~0.106 mg C/kJ; n =20) moderate-fat (MFD: 30%E...
Plasma retinol and indices of iron status were measured in 148 school children (6-12 years) receiving a soup fortified with vitamin C for period 15 weeks. The most significant change serum (P = 0.0005) transferrin saturation 0.0002) was seen subjects plasma > 40 μg/dl, while < 20 μg/dl showed no response. Serum ferritin improved the categories suggesting that absorption not impaired by marginal A status, but it rather mobilisation from stores affected. Changes correlated positively...