Fereshteh Torabi
A5013104202- CAR-T cell therapy research
- Cutaneous lymphoproliferative disorders research
- T-cell and B-cell Immunology
- Probiotics and Fermented Foods
- Single-cell and spatial transcriptomics
- Medical Malpractice and Liability Issues
- Proteins in Food Systems
- Patient Safety and Medication Errors
- Skin Diseases and Diabetes
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- Pharmaceutical Practices and Patient Outcomes
- Congenital heart defects research
- Genomics and Chromatin Dynamics
- Meat and Animal Product Quality
- Extracellular vesicles in disease
- Dermatology and Skin Diseases
- Mesenchymal stem cell research
- Genetic Neurodegenerative Diseases
- Tissue Engineering and Regenerative Medicine
- Epigenetics and DNA Methylation
- Medical History and Research
- Lymphoma Diagnosis and Treatment
- Quality and Safety in Healthcare
- Food composition and properties
Wellcome Sanger Institute
2023-2024
Agricultural Sciences and Natural Resources University of Khuzestan
2020-2021
Ministry of Health and Medical Education
2016-2018
Tehran University of Medical Sciences
2015
Human prenatal skin is populated by innate immune cells, including macrophages, but whether they act solely in immunity or have additional functions morphogenesis unclear. Here we assembled a comprehensive multi-omics reference atlas of human (7-17 post-conception weeks), combining single-cell and spatial transcriptomics data, to characterize the microanatomical tissue niches skin. This revealed that crosstalk between non-immune cells underpins formation hair follicles, implicated scarless...
Cutaneous T cell lymphoma (CTCL) is a potentially fatal clonal malignancy of cells primarily affecting the skin. The most common form CTCL, mycosis fungoides, can be difficult to diagnose, resulting in treatment delay. We performed single-cell and spatial transcriptomics analysis skin from patients with fungoides-type CTCL an integrated comparative human atlas datasets healthy inflamed revealed co-optation helper 2 (T
Enhancers are key gene regulatory elements that ensure the precise spatiotemporal execution of developmental expression programmes. However recent findings indicate approaches to identify enhancers may not capture full repertoire active in mammalian genomes. Here, we combine massively parallel enhancer assays with chromatin structure and transcriptome profiling functionally annotate genome-wide human induced pluripotent stem cells. We find a substantial fraction (~40%) accessible regions...
The quality parameters of the optimized symbiotic ultrafiltrated white cheese (OC; containing demineralized whey powder and inulin) treated with microbial transglutaminase enzyme (MTE) was compared two commercial probiotic (PC) non-probiotic (NC) cheeses. counts (Lactobacillus acidophilus LA5) total lactic acid bacteria, pH were significantly decreased during 60-day cold storage period. Fat protein contents, stress levels at rupture point, Young's modulus meaningfully increased until 30th...
Abstract Cutaneous T-cell lymphoma (CTCL) is a potentially fatal clonal malignancy of T cells primarily affecting the skin. The most common form CTCL, mycosis fungoides (MF), can be difficult to diagnose resulting in treatment delay. pathogenesis CTCL not fully understood due limited data from patient studies. We performed single-cell RNA sequencing and spatial transcriptomics profiling skin patients with MF-type an integrated comparative analysis human cell atlas datasets healthy skin,...
Summary Human prenatal skin is populated by innate immune cells including macrophages, and whether they act solely in immunity or have additional functions morphogenesis unclear. We assembled the first comprehensive multi-omic reference atlas of human (7-16 post-conception weeks), combining single cell spatial transcriptomic data, to characterise skin’s microenvironmental cellular organisation. This revealed that crosstalk between non-immune underpins formation hair follicles, has...
Abstract Introduction and aims Hair-bearing skin organoids (SkOs) are a complex three-dimensional (3D) model that faithfully recapitulates human as multicellular organ with appendage structures. The development of such models provides unique potential for investigating translational dermatology. Although this answers many demands an investigative tool, one obvious limitation is the absence immune cells in SkOs. Our aim to generate coculture systems SkOs macrophages investigate how influence...
Abstract Embryonic development requires the accurate spatiotemporal execution of cell lineage-specific gene expression programs, which are controlled by transcriptional enhancers. Developmental enhancers adopt a primed chromatin state prior to their activation; however how this enhancer is established, maintained, and it affects regulation developmental networks remains poorly understood. Here, we use comparative multi-omic analyses human mouse early embryonic identify subsets...
Texture, Color and Sensory Characteristics of Synbiotic Ultrafiltrated White Cheese Treated with Microbial Transglutaminase Enzyme During Storage Period
Introduction: The most common variation of the axillary components in human is Langer’s arch (axillopectoral muscle). For first time, Ramsay 1795 explained this variation, and 1864, Langer confirmed called it as Langer. Case Presentation: During routine dissection, we encountered an aberrant slip muscle fascia expanded from latissimus dorsi to pectoralis major. Conclusions: very clinically important, because may entrap implicate neurovascular bundle. Also important for surgeons during...