A5101568452- Traditional Chinese Medicine Analysis
- Lymphoma Diagnosis and Treatment
- Traditional Chinese Medicine Studies
- Plant-based Medicinal Research
- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Pharmacological Effects of Natural Compounds
- Cancer Mechanisms and Therapy
- Pregnancy-related medical research
- CNS Lymphoma Diagnosis and Treatment
- Bee Products Chemical Analysis
- Breast Cancer Treatment Studies
- Protein Degradation and Inhibitors
- PARP inhibition in cancer therapy
- Metabolism, Diabetes, and Cancer
- Fermentation and Sensory Analysis
- Computational Drug Discovery Methods
- Folate and B Vitamins Research
- Liver Disease Diagnosis and Treatment
- Essential Oils and Antimicrobial Activity
- Metabolism and Genetic Disorders
- Advanced Radiotherapy Techniques
- Phytoestrogen effects and research
- Chromatography in Natural Products
- Spine and Intervertebral Disc Pathology
Shandong University of Technology
2025
Beijing University of Chinese Medicine
2014-2024
South China Agricultural University
2024
First Hospital of Jilin University
2023
Jilin University
2023
Zhongshan Hospital
2006-2020
Fudan University
2007-2020
Tianjin Medical University
2016
Sichuan Academy of Agricultural Sciences
2016
Shanghai Medical College of Fudan University
2006
To identify core bacterial communities and volatile compounds to investigate their relationships in Doubanjiang, a Chinese traditional red pepper paste.Two main culture-independent methods, polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) MiSeq sequencing technique, were used composition. Headspace solid-phase microextraction combined with gas chromatography-mass spectrometry (HS-SPME-GC-MS) was isolate organic compounds. Partial least squares (PLS) regression...
Metabolic-associated fatty liver disease (MAFLD) is a common chronic metabolic worldwide that seriously threatens human health. The Xiaoji-chenpi formula (XCF), derived from QingGanSan (QGS), has previously been proven to be clinically effective in MAFLD. However, its pharmacological activity and mechanism have not studied depth. In this study, we explored determined the optimal amounts of cholesterol fat additives (4% 20%, respectively) for modeling zebrafish MAFLD via orthogonal tests....
Chrysanthemum flower is a common traditional Chinese medicine (TCM). In this work, pressurized hot water extraction (PHWE) followed by headspace solid-phase microextraction (HS-SPME) and GC-MS was developed for the determination of three main active volatile compounds eucalyptol, camphor, borneol in flowers from four different growing areas China internal standard method. The parameters PHWE HS-SPME were optimized. method also validated. results showed that PHWE-SPME-GC-MS simple, rapid,...
Clinical efficacy and mechanism of Qishen Yiqi Dripping Pills(QSYQ) have been well researched, but the compatibility underlying its therapeutic effect still requires further analysis. This study aims to explore QSYQ in treating myocardial ischemia. UPLC-Q-Exactive Orbitrap-MS technique was used obtain absorbed blood components QSYQ. Target proteins were collected screened using TCMSP, TCMIP, SwissTargetPrediction databases. Disease related ischemia obtained through GeneCards, OMIM, DisGeNET...
Abstract Angelica sinensis (danggui in Chinese) is a common traditional Chinese medicine (TCM), and its essential oil has been used for the treatment of many diseases such as hepatic fibrosis. Z ‐Ligustilide found to be an important active component TCM oil. In this work, first time, headspace single‐drop microextraction (HS‐SDME) followed by gas chromatography‐mass spectrometry (GC‐MS) was developed determination ‐ligustilide rabbit plasma after oral administration danggui. The extraction...
In this study, The fingerprints of Cuscutae Semen and its processed products such as qing chao pin (QCP), jiu zhi (JZP), yan (YZP) were performed using high performance liquid chromatography. Ten chromatographic peaks selected characteristic peaks, the relative peak areas (RPA) which calculated for quantitative expression HPLC fingerprints. RPA 10 subjected to principal component analysis (PCA) in order classify raw products. Principal analytical data showed that could be clustered...
Objectives One-carbon metabolism (OCM) significantly influences fetal growth and neurodevelopment through transferring methyl group to biomolecules, during which folate, methionine, choline betaine function as donor nutrients, while vitamin B 2 , 6 12 enzyme cofactors, homocysteine (Hcy) S-adenosyl methionine (SAM) are functional metabolites. This study aimed assess blood OCM index levels explore their relationships among Chinese pregnant women. Methods Data were obtained from the baseline...
<title>Abstract</title> <italic>Tribolium castaneum</italic> (Herbst), which resides in shaded areas avoiding daylight, has developed various adaptation strategies to cope with ultraviolet (UV) stress. In this study, we utilized 16S rRNA amplicon sequencing assess the diversity of bacterial communities within <italic>T. following exposure ultraviolet-A and ultraviolet-B for different durations, elucidate role microbiome host response UV This study revealed that irradiation affected relative...
The whole process quality control and management of traditional Chinese medicine (TCM) decoction pieces is a system engineering, involving the base environment, seeds seedlings, harvesting, processing other multiple steps, so accurate identification factors in TCM production that may induce risk, as well reasonable measures are very important. At present, concept risk mainly concentrated aspects regulations, etc. There no comprehensive analysis on possible risks pieces, or summary effective...
Intervertebral disc degeneration (IDD) is a common disease with high morbidity rate, which results in significant deterioration the quality of life patients. MicroRNAs (miRNAs/miRs) are class endogenous small non‑coding RNAs that influence target genes and serve critical roles numerous biological processes. However, role miR‑489‑3p lumbar yet to be elucidated. In present study, human NP cells were treated 10 ng/ml lipopolysaccharide (LPS) for 24 h investigate IDD an <em>in vitro</em> model....
Gansu province,which spans the Yangtze river,is in upper reaches of Yellow river and located at intersection Qinghai-Tibet plateau,the Inner Mongolia plateau Loess plateau. All these areas are highly respected by doctors all ages as they have enriched resources traditional Chinese medicines. In interaction between heavens earth,the people future has been passed down to present. As one abbreviations province, " Long" is not only symbol representative region,but also authentic...
Objective To establish a method to compare the difference of exposure component oral taking different part ofPueraria Lobata (Willd.) Ohwi in intestine.Methods After incubation puerarin,extraction Radix Puerariae and Flos with S9,the mixtures were centrifuged get supernatant for analysis HPLC.Results The research showed that metabolic rate puerarin was higher than extractions because concentration enzyme.The between fingerprints indicated there chemical components such two parts Kudzuvine...
Objective: To analyze the clinical features, treatment and outcomes of primary lymphoma bone (PLB) . Methods: The data 11 PLB patients were retrospectively analyzed. Results: enrolled in our study including 7 females 4 males. median age was 45 years old. main histologic type diffuse large B cell anaplastic lymphoma. Of cases, 3 cases at stage ⅠE, 2 ⅡE, 6 ⅣE respectively. treated with chemotherapy radiotherapy, total joint arthroplasty chemotherapy, alone 5 got complete remission, partial...
Abstract Kinase‐targeted therapy has been established as a widely used strategy to treat liver cancer. However, number of kinase gatekeeper mutations are clinically observed cause acquired drug resistance during the therapy, which can be overcome by pan‐kinase inhibitors. Here, we create systematic profile inhibitors against clinical in cancer pathogenesis integrating computational modeling and experimental assay. With able identify those that potentially or confer sensitivity certain The...