Mengyuan Zhang

ORCID: 0000-0001-5097-1946
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About
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Research Areas
  • Algebraic Geometry and Number Theory
  • Genetic Mapping and Diversity in Plants and Animals
  • Circular RNAs in diseases
  • Rice Cultivation and Yield Improvement
  • Genomics and Phylogenetic Studies
  • MicroRNA in disease regulation
  • Commutative Algebra and Its Applications
  • Gut microbiota and health
  • RNA Interference and Gene Delivery
  • Cancer-related molecular mechanisms research
  • Hydrogels: synthesis, properties, applications
  • Sulfur Compounds in Biology
  • Electrospun Nanofibers in Biomedical Applications
  • Advanced Algebra and Geometry
  • Immune Cell Function and Interaction
  • HIV Research and Treatment
  • Photosynthetic Processes and Mechanisms
  • Genetic and phenotypic traits in livestock
  • Plant Pathogens and Fungal Diseases
  • Extracellular vesicles in disease
  • Epigenetics and DNA Methylation
  • Algebraic structures and combinatorial models
  • Helicobacter pylori-related gastroenterology studies
  • Topological and Geometric Data Analysis
  • Geometric Analysis and Curvature Flows

Anhui Academy of Agricultural Sciences
2024-2025

Ministry of Agriculture and Rural Affairs
2025

Anhui Agricultural University
2023-2025

Rice Research Institute
2024-2025

Inner Mongolia University
2025

Henan University of Science and Technology
2025

Xi'an Jiaotong University
2021-2024

Beijing Ditan Hospital
2022-2024

Capital Medical University
2022-2024

Shanghai University of Traditional Chinese Medicine
2023-2024

The Hoffmeister effect of inorganic salts is verified as a promising way to toughen hydrogels, however, the high concentration may be accompanied by poor biocompatibility. In this work, it found that polyelectrolytes can obviously elevate mechanical performances hydrogels through effect. introduction anionic poly(sodium acrylate) into poly(vinyl alcohol) (PVA) hydrogel induces aggregation and crystallization PVA boost properties resulting double-network hydrogel: elevation 73, 64, 28, 135,...

10.1002/adma.202301551 article EN Advanced Materials 2023-03-20

Stable mechanical properties under cyclic loads are critical for the applications of hydrogels in flexible electronics and tissue engineering. However, most existing tough still face obvious notch sensitivity suffer from fatigue fracture continuous load. Designing with multifunctional properties, such as high stretchability, toughness, excellent antifatigue fracture, through a facile strategy is on demand. In this work, nanocomposite comprehensive were prepared by one-pot polymerization...

10.1021/acs.chemmater.1c01790 article EN Chemistry of Materials 2021-08-12

Objective MiRNA-766-3p has been shown to be associated with a variety of cancers.However, few studies have done in gastric cancer (GC).This study explores the mechanism miR-766-3p GC.Methods The potential targets microRNA (miRNA) were predicted using Tarbase and Targetscan databases.The results are intersected differential genes (DEGs) (fold change > 1.5, P < 0.05) obtain core targets.The hub screened by constructing PPI networks (degree 5, expression 0.5).Validating immunohistochemistry...

10.7150/jca.90321 article EN cc-by-nc Journal of Cancer 2024-01-01

Abstract Background Colony‐stimulating factor 1 receptor (CSF1R)‐related disorder (CRD) is a rare autosomal dominant disease. The clinical and genetic characteristics of Chinese patients have not been elucidated. Objective objective the study to clarify core features influence factors CRD in China. Methods Clinical genetic‐related data China were collected. Mini‐Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Sundal MRI Severity Score evaluated. Whole exome sequencing...

10.1002/mds.29764 article EN Movement Disorders 2024-03-11

The eating and cooking quality (ECQ) directly affects the taste of rice, being closely related to factors such as gelatinization temperature (GT), gel consistency (GC) amylose content (AC). Mining quantitative trait loci (QTLs), gene controlling ECQ-related traits is vital. A genome-wide association study on was conducted, combining 1.2 million single nucleotide polymorphisms (SNPs) with phenotypic data 173 rice accessions. Two QTLs for GT, one GC five AC were identified, which two found in...

10.3390/ijms25010630 article EN International Journal of Molecular Sciences 2024-01-03

Breast cancer has attracted tremendous research interest in treatment development as one of the major threats to public health. The use non-viral carriers for therapeutic DNA delivery shown promise treating various types, including breast cancer, due their high loading capacity, cell transfection efficiency, and design versatility. However, cytotoxicity large sizes often raise safety concerns hinder applications clinic. Here we report a novel nanoparticle formulation (termed NP-Chi-xPEI)...

10.3390/nano12040584 article EN cc-by Nanomaterials 2022-02-09

In China, Fusarium pseudograminearum has emerged as a major pathogen causing crown rot (FCR) and caused significant losses. Studies on the pathogen’s properties, especially its mating type trichothecene chemotypes, are critical with respect to disease epidemiology food/feed safety. There currently few available reports these issues. This study investigated species composition, idiomorphs, genotypes of spp. FCR in Henan, China. A shift F. pseudograminearum-induced was found present study. Of...

10.3390/jof10040240 article EN cc-by Journal of Fungi 2024-03-22

Imperatorin (IMP) is a naturally occurring furanocoumarin with beneficial biological activities such as anticancer, antioxidant, and neuromodulatory properties. Currently, the protective effects mechanisms of IMP on oxidative stress experienced by mouse oocytes after vitrification-thawing remain unclear. To investigate influence oocyte development vitrification-thawing, we added different concentrations to vitrification thawing media. Results indicated that addition 40 μM enhanced post-thaw...

10.3390/ani15050661 article EN cc-by Animals 2025-02-25

There is a growing demand for natural and potent α-glucosidase inhibitors due to the rising prevalence of diabetes. In this study, newly identified inhibitory peptides were from tryptic hydrolysate hemp seed proteins based on peptidomics in silico analysis. A total 424 peptides, primarily derived four cupin-type-1 domain-containing proteins, identified, 13 ultimately selected validation their higher PeptideRanker scores, solubility, non-toxicity, favorable ADMET properties. Molecular docking...

10.3390/ijms26052222 article EN International Journal of Molecular Sciences 2025-02-28

The aging of the immune system is associated with various diseases. It worth exploring changes in aging. Previous studies have shown that aged T cells enhanced expression co-inhibitory molecules. However, it remains unclear whether NK exhibit similar characteristics to cells. objective our research was clarify this aspect. This study included 98 adults 24-90 years (50 males and 48 females). We detected subset peripheral blood receptors on among donors different age groups by flow cytometry....

10.2147/ijgm.s452476 article EN cc-by-nc International Journal of General Medicine 2024-02-01

Increasing evidence has suggested that alterations in the gut microbiome are correlated with autoimmune neurologic disorders, yet causal relationship between them to be established.

10.3389/fmicb.2024.1337632 article EN cc-by Frontiers in Microbiology 2024-04-24

The aim of this study was to investigate the effect hesperidin on liver and kidney dysfunctions induced by nickel. mice were divided into six groups: nickel treatment with 80 mg/kg, 160 320 mg/kg groups, 0.5% CMC-Na group, blank control group. Histopathological techniques, biochemistry, immunohistochemistry, TUNEL method used changes in structure, functions, oxidative injuries, apoptosis kidney. results showed that could alleviate weight loss histological injuries nickel, increase levels...

10.3389/fvets.2024.1424711 article EN cc-by Frontiers in Veterinary Science 2024-06-25
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