A5014548426- Exercise and Physiological Responses
- Heat shock proteins research
- Adipose Tissue and Metabolism
- Muscle metabolism and nutrition
- Muscle Physiology and Disorders
- Sports Performance and Training
- Sports injuries and prevention
- Thermoregulation and physiological responses
- Tissue Engineering and Regenerative Medicine
- Cardiovascular Effects of Exercise
- Electrospun Nanofibers in Biomedical Applications
- Physical Activity and Health
- Nutrition and Health in Aging
- Spaceflight effects on biology
- Hormonal and reproductive studies
- Liver Disease Diagnosis and Treatment
- Mobile Health and mHealth Applications
- Autophagy in Disease and Therapy
- Genetics and Physical Performance
- Alcohol Consumption and Health Effects
- Fatty Acid Research and Health
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Physical Education and Training Studies
- Gut microbiota and health
- High Altitude and Hypoxia
University of Palermo
2011-2025
Università degli Studi eCampus
2016-2024
Istituto Euro Mediterraneo di Scienza e Tecnologia
2016-2024
SMART Global Holdings (United States)
2019-2022
SMART Reading
2019-2022
ORCID
2021
Italian University Line
2021
Stellenbosch University
2009-2019
Italian Society of Physiotherapy
2017
Clinica Luganese Moncucco
2005-2016
Abstract Recent studies have correlated physical activity with a better prognosis in cachectic patients, although the underlying mechanisms are not yet understood. In order to identify pathways involved activity-mediated rescue of skeletal muscle mass and function, we investigated effects voluntary exercise on cachexia colon carcinoma (C26)-bearing mice. Voluntary prevented loss ultimately increasing survival C26-bearing We found that autophagic flux is overloaded both murine models but...
Context: Plyometric training has been successfully used in different sporting contexts. Studies that investigated the effect of plyometric on muscle morphology are limited, and results controversial with regard to which fiber type is mainly affected. Objective: To analyze skeletal structural ultrastructural change induced by an acute bout exercise determine fibers predominantly damaged. Design: Descriptive laboratory study. Setting: Research laboratory. Patients or Other Participants: Eight...
We have studied the pathophysiology of vascular obstruction induced by Plasmodium falciparum-parasitized erythrocytes with use an ex vivo microcirculatory preparation perfused red cells infected knobless and knobby clones FCR-3 strain. find that parasitized erythrocyte membrane knobs are indispensable for generation circulatory obstruction. Uninfected incubated in culture early or late forms clone all failed to obstruct microcirculation, although exhibiting various effects on bulk viscosity...
Abstract Heat shock protein 60 (Hsp60) is a chaperone localizing in skeletal muscle mitochondria, whose role poorly understood. In the present study, levels of Hsp60 fibres entire posterior group hindlimb muscles ( gastrocnemius , soleus and plantaris ) were evaluated mice after completing 6-week endurance training program. The correlation between expression four isoforms peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC1α) investigated only . Short-term...
The purpose of this study was to analyze the differences in standing balance during dominant and nondominant one-legged stance among athletes different sports sedentary subjects. right-footed subjects four groups (sedentary, n = 20; soccer, basketball, windsurfer 20) underwent 5-sec unipedal (left right foot) stabilometric analysis with open eyes closed measure center pressure (COP) sway path COP velocity (mean value, anteroposterior, laterolateral millimeters per second). soccer group...
Alcoholism is one of the most devastating diseases with high incidence, but knowledge its pathology and treatment still plagued gaps mostly because inherent limitations research patients. We developed an animal model for studying liver histopathology, Hsp (heat-shock protein)-chaperones involvement, response to treatment.The system was standardized using mice which ethanol orally administered alone or in combination Lactobacillus fermentum following a precise schedule over time applying, at...
Background: This research explored how tele-exercise influenced physical fitness and mental well-being in individuals with without disabilities different training habits. Methods: One hundred ninety-three participants were categorized into two groups: athletes non-athletes. Participants involved either synchronous or asynchronous programs of three sessions workouts per week, lasting eight weeks. Psychological was evaluated pre- vs. post-intervention by the WHO-Five Well-Being Index (WHO-5),...
In athletes, airway inflammatory cells were found to be increased in induced sputum or bronchial biopsies. Most data obtained after exposure cold and dry air at rest during exercise. Whether training affects epithelial small airways is unknown.To test whether endurance under standard environmental conditions causes damage inflammation the of mice.Formalin-fixed, paraffin-embedded lung sections sedentary (n = 14) endurance-trained 16) Swiss mice baseline 15, 30, 45 days training. The...
A new role for fat supplements, in particular conjugated linoleic acid (CLA), has been delineated steroidogenesis, although the underlying molecular mechanisms have not yet elucidated. The aims of present study were to identify pathway stimulated by CLA supplementation using a cell culture model and determine whether this same is also vivo associated with exercise. In vitro, Leydig tumour rat cells (R2C) supplemented different concentrations exhibited increasing testosterone biosynthesis...
Conjugated linoleic acid (CLA) has been reported to improve muscle hypertrophy, steroidogenesis, physical activity, and endurance capacity in mice, although the molecular mechanisms of its actions are not completely understood. The aim present study was identify whether CLA alters expression any peroxisome proliferator-activated receptor γ coactivator 1α (PGC1α) isoforms, evaluate possible existence fibre-type-specific hypertrophy gastrocnemius plantaris muscles. Mice were randomly assigned...
The purpose of this study was to investigate if exertional rhabdomyolysis induced by an acute bout plyometric exercise in untrained individuals associated with histological characteristics skeletal muscle, creatine kinase (CK) polymorphism or secondary damage. Twenty-six healthy male completed a (10 sets 10 maximal squat jumps, each standardised achieve at least 95% individual jump height). Blood samples were taken and perceived pain scored immediately before the intervention 6 hours, 1, 2 3...
Besides its substantial role in eye lens, αB-crystallin (HSPB5) retains fundamental function striated muscle during physiological or pathological modifications. In this study, we aimed to analyse the cellular and molecular factors driving functional response of HSPB5 protein different muscles from mice subjected an acute bout non-damaging endurance exercise C2C12 myocytes upon exposure pro-oxidant environment, chosen as “in vivo” vitro” models a stressing conditions, respectively. To end,...
Laboratory teaching in sport and exercise sciences universities is of fundamental importance as it provides students with the necessary hands-on skills that are indispensable to future kinesiologists. However, due COVID-19 pandemic, lockdown missed opportunity acquire laboratory skills. Here we report solutions adopted by a blended science Master’s degree program an online Italian university ensure didactic continuity practice-oriented activities during period lockdown. In order mitigate...
Several studies focused on the macroscopic architecture of increased cardiac wall induced by exercise training. Our goal was to evaluate myocardiocyte, interstitial and vascular component, connexin-43 expression in endurance-trained mouse hearts. Sixty-three 10-week-old male Swiss mice were divided into four sedentary groups (C0, C15, C30 C45) three exercised respectively for 15 (T15-D; running intensity [RI]: 3.18 m/min; duration [RD]: 75 min/first week 150 min/second week), 30 (T30-D; RI:...
The purpose of this study was to investigate skeletal muscle changes induced by an acute bout plyometric exercise (PlyEx) both before and after PlyEx training, understand if titin is affected differently training. Healthy untrained individuals (N = 11) completed the 1stPlyEx (10 × 10 squat-jumps, 1-min rest). Thereafter, six subjects 8 wk PlyEx, while five controls abstained from any jumping activity. Seven days last training session, all 2ndPlyEx. Blood samples were collected 6 h 1, 2, 3, 4...
Probiotics are live microorganisms that yield health benefits when consumed, generally by improving or restoring the intestinal flora (microbiota) as part of muco-microbiotic layer bowel. In this work, mice were fed with ethanol alone in combination probiotic Lactobacillus fermentum (L. fermentum) for 12 weeks. The modulation NF-κB signaling pathway induction Hsp60, Hsp90, and IkB-α occurred jejunum. L. inhibited IL-6 expression downregulated TNF-α transcription. inactivation concurred...
Probiotics have shown the potential to counteract loss of muscle mass, reduce physical fatigue, and mitigate inflammatory response following intense exercise, although mechanisms by which they work are not very clear. The objective this review is describe main harmful effects alcohol on skeletal provide important strategies based use probiotics. excessive consumption a worldwide problem has been be crucial in progression alcoholic liver disease (ALD), for which, date, only therapy available...
In the last few years, a major goal of cardiac research has been to drive stem cell differentiation replace damaged myocardium. Several groups have attempted differentiate potential cells (CSCs) using bi- or three-dimensional systems supplemented with growth factors molecules acting as differentiating substances. We hypothesize that these failed induce complete because they lacked an architectural space. present study, we isolated pool small proliferating and fibroblast-like from adult rat...