A5047501480- Fatty Acid Research and Health
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Nutrition and Health in Aging
- Cholesterol and Lipid Metabolism
- Muscle metabolism and nutrition
- Exercise and Physiological Responses
- Frailty in Older Adults
- Cancer, Hypoxia, and Metabolism
- Cardiovascular and exercise physiology
- Clinical Nutrition and Gastroenterology
- Nutritional Studies and Diet
- Diet, Metabolism, and Disease
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Eicosanoids and Hypertension Pharmacology
- Sustainable Building Design and Assessment
- Food Allergy and Anaphylaxis Research
- Coconut Research and Applications
- IL-33, ST2, and ILC Pathways
- Adrenal and Paraganglionic Tumors
- Lipid metabolism and biosynthesis
- Obesity, Physical Activity, Diet
- Sports Performance and Training
- Effects and risks of endocrine disrupting chemicals
- Apelin-related biomedical research
Universidade Federal de Lavras
2015-2024
Federal Center for Technological Education of Minas Gerais
2020
Universidade Federal do Paraná
2010-2015
Instituto de Pesquisas Jardim Botânico do Rio de Janeiro
2015
Cancer chemotherapy is associated with neutropenia and impaired neutrophil function. This study aimed to investigate whether supplementation low dose fish oil (FO), providing n-3 polyunsaturated fatty acids, in cancer patients receiving after surgical tumor (mainly gastrointestinal) removal able improve the function of blood neutrophils. Patients (n = 38) (5-fluorouracil leucovorin) were randomized into two groups; one group (control) did not receive a supplement, while other (FO) received 2...
Obesity is commonly associated with diabetes, cardiovascular diseases and cancer. The purpose of this study was to determinate the effect a lower dose fish oil supplementation on insulin sensitivity, lipid profile, muscle metabolism in obese rats.Monosodium glutamate (MSG) (4 mg/g body weight) injected neonatal Wistar male rats. Three-month-old rats were divided normal-weight control group (C), coconut fat-treated normal weight (CO), oil-treated (FO), (Ob), (ObCO) (ObFO). Obese...
Fish oil (FO) has been shown to affect cancer cachexia, tumor mass, and immunity cell. n-3 PUFA, specifically α-linolenic fatty acid (ALA), controversial effects. We investigated this in nontumor-bearing Wistar rats fed regular chow (C), supplemented with FO or Oro Inca (OI), Walker 256 tumor-bearing (W), (WFO) OI (WOI). Rats were (1g/kg body weight/day) during 4 wk then the groups inoculated cells suspension 14 days later animals killed. WFO increased EPA fivefold DHA 1.5-fold tissue...
This study investigated the effect of interval training on blood biochemistry and immune parameters in type 1 diabetic rats.Male Wistar rats were divided into four groups: sedentary (SE, n = 15), (IT, 17), (DSE, (DIT, 17). Diabetes was induced by i.v. injection streptozotocin (60 mg/kg). Swimming Interval Training consisted 30-s exercise with rest, for 30 minutes, during 6 weeks, times a week, an overload 15% body mass. Plasma glucose, lactate, triacylglycerol total cholesterol...
Immune function changes with ageing and is influenced by physical activity (strength training, ST) diet (fish oil, FO). The present study investigated the effect of FO ST on immune system elderly women. Forty-five women (64 ( sd 1·4) years) were assigned to for 90 d (ST; n 15), plus 2 g/d (ST90; 15) or 60 followed (ST150; 15). Training was performed three times per week, 12 weeks. A number innate (zymosan phagocytosis, lysosomal volume, superoxide anion, peroxide hydrogen) adaptive (cluster...
Polyunsaturated fatty acids n-3 (PUFA n-3) have shown effects in reducing tumor growth, particular eicosapentaenoic acid (EPA) and docosahexaenoic (DHA) abundantly present fish oil (FO). When these are provided the diet, they alter functions of cells, particularly immune cells. However, α-linolenic (ALA), which is precursor EPA DHA, controversial. Thus, our objective was to test effect this parental acid.Non-tumor-bearing tumor-bearing Wistar rats (70 days) were supplemented with 1 g/kg body...
Food allergy is an abnormal immune response to antigens introduced into the body through food. Its prevalence has increased in developed and developing countries. Natural products are traditionally used alleviate treat diseases, diet can play a role both prevention management of food allergy. The effects capsaicin as anti-oxidant, anticarcinogenic, anti-inflammatory energy expenditure suppression fat accumulation have been demonstrated. This study evaluated effect oral supplementation with on model.
The objective of the present work was to study renal function healthy and tumor-bearing rats chronically supplemented with fish oil (FO), a source n-3 polyunsaturated fatty acids. Weanling male were divided in two groups, one control (C) another orally for 70 days FO (1 g/kg body weight). After this time, half animals each group injected right flank suspension Walker 256 tumor cells (W WFO). W had less proteinemia reflecting cachectic proteolysis, reversed fact. Tumor weight gain also...
It has been hypothesized that oils containing high levels of omega-3 polyunsaturated fatty acids, such as canola and fish oil, could counteract some the adverse effects induced by phthalates. In present study, influence different oily vehicles on di-butyl phthalate (DBP)-induced testicular toxicity lipid profile was investigated. Pregnant Wistar rats were treated oral gavage from gestation days 13 to 20 with DBP (500 mg/kg/day) diluted in three vehicles: corn, or oil. Male fetuses analyzed...
This study investigated the mechanisms by which β-hydroxy-β-methylbutyrate (HMB) administration in rats reduces Walker-256 tumor growth. Male Wistar were supplemented with HMB (76 mg/kg/day) (HW), or a placebo (W), during 8 wk gavage. At 6th wk, inoculated suspension of Walker 256 cells (3 × 107/mL). Fifteen days after inoculation, HW group showed higher glycemia (109.4 ± 5.53 vs. 89.87 7.02 mg/dL, P < 0.05) and lower spleen (1.35 0.05 1.65 0.12 g, weights (9.64 1.07 13.55 1.19 compared to W...
Obesity is considered a low-grade inflammatory state and has been associated with increased acute phase proteins as well changes in serum fatty acids. Few studies have assessed associations between acids morbidly obese patients.To investigate the relationship (C-Reactive Protein, Orosomucoid, Albumin) patients.Twenty-two patients were enrolled this study. Biochemical clinical data obtained before bariatric surgery, measured preoperative serum.Orosomucoid was negatively correlated lauric acid...
We investigated the effect of fish oil (FO) supplementation on tumor growth, cyclooxygenase 2 (COX-2), peroxisome proliferator-activated receptor gamma (PPARγ), and RelA gene protein expression in Walker 256 tumor-bearing rats. Male Wistar rats (70 days old) were fed with regular chow (group W) or supplemented 1 g/kg body weight FO daily WFO) until they reached 100 age. Both groups then inoculated a suspension ascitic cells (3×107 cells/mL). After 14 killed, total RNA was isolated from...
OBJETIVO: Investigar o efeito do treinamento de salto associado à suplementação com óleo peixe (1g/kg peso corporal/dia) em ratos portadores tumor Walker 256, sobre parâmetros bioquímicos caquexia e crescimento tumoral.MÉTODOS: Oitenta Ratos foram divididos sedentário sem ou (S SW), exercitado (EX EXW), suplementado (SO SWO) (EXO EXWO). Sessões consistiram 10 séries duração 30 segundos intervalo 1 minuto entre cada série. Após seis semanas treinamento, células 256 inoculadas após 15 dias os...
Present study investigated which diet, high-carbohydrate (HCD) or high-fat (HFD), most effectively induces classical characteristics of obesity in mice. Mice were fed commercial chow (control), an HCD, HFD for 12 weeks. and HCD increased body weight, fat mass, glycaemia, whereas the augmented insulinemia. In kidney, caused albuminuria, reductions fractional Na+ excretion, Thromboxane B2 (TXB2) urinary flow, reduced glomerular filtration, plasma osmolality, TXB2 Prostaglandin E2 excretion....
Com o aumento do consumo de ácidos graxos poli-insaturados (AGPI) n-6 em detrimento dos n-3, há maior produção metabólitos que apresentam potentes características pró-inflamatórias, trombóticas e agregadoras. Tais efeitos são distintos das ações derivados AGPI n-3. Atualmente, estudos modelos animais humanos portadores doença investigam uso n-3 como potenciais modulares da função renal, pode estar frequentemente alterada doenças com cunho inflamatório. Em animais, a suplementação foi capaz...
Fish oil (FO) supplementation, rich in n‐3 PUFA, has a positive effect on various diseases, including cancer, kidney diseases and diabetes. High fat (HFD) and/or high carbohydrate (HC) diets promote obesogenic effects induce insulin resistance.The objective of this study was evaluate the chronic fish supplementation renal function parameters mice fed with HFD or HC diets. Six weeks male were divided three groups different during eight weeks: regular rodent chow (S), HFD. After this, they...