A5083410684- Nutritional Studies and Diet
- Diet and metabolism studies
- Nutrition, Genetics, and Disease
- Obesity, Physical Activity, Diet
- Consumer Attitudes and Food Labeling
- Fatty Acid Research and Health
- Muscle metabolism and nutrition
- Folate and B Vitamins Research
- Child Nutrition and Water Access
- Metabolomics and Mass Spectrometry Studies
- Bioinformatics and Genomic Networks
- Iron Metabolism and Disorders
- Sleep and related disorders
- Nutrition and Health in Aging
- Pregnancy and Medication Impact
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Gut microbiota and health
- Antioxidant Activity and Oxidative Stress
- HIV-related health complications and treatments
- Congenital Anomalies and Fetal Surgery
- Obstructive Sleep Apnea Research
- Sleep and Wakefulness Research
- Infant Development and Preterm Care
- Organ Transplantation Techniques and Outcomes
- Agriculture Sustainability and Environmental Impact
University College Dublin
2019-2024
Food for Health Ireland
2019-2021
Agriculture and Food
2019-2021
Universidade de São Paulo
2016-2021
Department of Medical Sciences
2020
Clinics Hospital of Ribeirão Preto
2020
Universidade Federal de Santa Catarina
2013
Micronutrients are in small amounts foods, act concert, and require variable of time to see changes health risk for disease. These first principles incorporated into an intervention study designed develop new experimental strategies setting target recommendations food bioactives populations individuals.
Plant-based diets have gained attention for their potential benefits on both human health and environmental sustainability. The objective of this study was to investigate the association plant-based dietary patterns with endogenous metabolites healthy individuals identify that may act as mediators associations between intake modifiable disease risk factors. Adherence assessed 170 adults using diet indexes (PDI). Individuals higher healthful PDI had lower BMI fasting glucose HDL-C, while...
The Brazilian Healthy Eating Index-Revised (BHEI-R) can be used to determine overall dietary patterns. We assessed the BHEI-R scores in children and adolescents, aged from 9 13 years old, associated its component with biomarkers of health exposure. Three 24-h recalls were generate BHEI-R. Biomarkers analyzed plasma red blood cells. Correlation tests, agreement, covariance analyses associate components biomarkers. Data 167 subjects used. strongest correlations between fruits, vegetables...
Targeted nutrition is defined as dietary advice tailored at a group level. Groups known metabotypes can be identified based on individual metabolic profiles. Metabotypes have been associated with differential responses to diet, which support their use deliver advice. We aimed optimise metabotype approach targeted by encompassing more specific recommendations nutrient and food intakes behaviours.Participants (n = 207) were classified into three four biomarkers (triacylglycerol, total...
Vitamins B2, B6, B12, and folate are essential for methylation reactions possibly influence the transport of polyunsaturated fatty acids in plasma red blood cells (RBC). Associations between B-vitamin biomarkers acid (FA) profile were analyzed Brazilian children adolescents. This cross-sectional study included 249 adolescents, aged 9–13 years old. Dietary intake was assessed by food frequency questionnaire healthy eating index (HEI). Biomarkers vitamins measured plasma. The FA metabolites...
Scope Effective strategies for tailoring dietary advice to individuals are urgently needed. The effectiveness of personalized nutrition delivered using a metabotype framework in improving quality and metabolic health biomarkers compared population‐level is investigated. Materials results A 12‐week parallel randomized controlled trial performed with 107 healthy adults. Individuals the group classified into metabotypes four markers (triacylglycerol, high‐density lipoprotein [HDL]‐cholesterol,...
This cross-sectional study aimed to investigate the nutritional status and dietary intake of HIV-infected children adolescents relationship between CD4 + T-cell count viral load. The sample was composed 49 subjects aged 7–17 years living in Florianópolis, Brazil. Nutritional assessed by height-for-age body mass index-for-age. Dietary a food frequency questionnaire. Spearman correlations multiple linear regressions were used determine energy, nutrient index-for-age mean values –0.26 ± 0.86...
Scope Previous work identified three metabolically homogeneous subgroups of individuals (“metabotypes”) using k ‐means cluster analysis based on fasting serum levels triacylglycerol, total cholesterol, HDL and glucose. The aim is to reproduce these findings describe metabotype groups by dietary habits incident disease occurrence. Methods results 1744 participants from the KORA F4 study 2221 FF4 are assigned clusters previously minimizing Euclidean distances. In both studies, assignment in...
In a 12-week randomised controlled trial, personalised nutrition delivered using metabotype framework improved dietary intake, metabolic health parameters and the metabolomic profile compared to population-level advice. The objective of present work was investigate patterns advice during intervention alterations in intake profiles obtain further insights into effectiveness framework. Forty-nine individuals were group subsequently classified metabotypes four biomarkers (triacylglycerol,...
This study evaluated the validity of nutrient and food group intakes estimated by an FFQ against biomarkers. A 71-item semiquantitative was administered to 210 Brazilian children adolescents aged 9–13 years. Intakes were correlated with biomarkers in plasma red blood cells. Correlations between nutrients their presented for animal protein, myristic acid (C14:0), EPA, DHA, β-carotene, folate, vitamins B3, B5 B6. Food groups as follows: fish products EPA DHA; milk dairy C14:0, pyridoxal...
Obesity is considered a low-grade inflammatory state and has been associated with increased acute phase proteins as well changes in serum fatty acids. Few studies have assessed associations between acids morbidly obese patients.To investigate the relationship (C-Reactive Protein, Orosomucoid, Albumin) patients.Twenty-two patients were enrolled this study. Biochemical clinical data obtained before bariatric surgery, measured preoperative serum.Orosomucoid was negatively correlated lauric acid...
Abstract Micronutrients and their metabolites are cofactors in proteins involved lipid metabolism. The present study was a subproject of the Harmonized Micronutrient Project (ClinTrials.gov # NCT01823744). Twenty participants were randomly selected from 136 children adolescents that consumed daily dose 12 vitamins 5 minerals supplementation for 6 weeks. 20 individuals divided into two pools 10 individuals, according to profile at baseline (Pool 1 with lower triglycerides, LDL, VLDL)....
This study aimed to investigate the association between DNA damage and blood levels of docosahexaenoic acid (DHA), eicosapentaenoic (EPA), retinol, beta-carotene riboflavin in Brazilian children adolescents.
Chronic kidney disease in children often determines poor nutritional status. Although renal transplantation (RTx) resolves endocrine and metabolic disorders, growth continues to be suboptimal excessive weight gain may result obesity.Evaluating the development of height body mass index transplanted adolescents identifying associated factors with final status.We reviewed medical records 17 patients regular follow-ups up 24 months after RTx. Nutritional status was assessed by height-for-age...
Bioelectrical impedance vectorial analysis (BIVA) can be considered a favorable method for evaluation and monitoring of nutritional hydration status without assumptions regarding body composition or requirement prediction formulas. The present study aimed to determine bivariate tolerance intervals the whole-body vector healthy term infants aged 1 3 months.This is descriptive cross-sectional study. Anthropometric bioelectrical data (800 mA-50 kHz) were obtained. Bivariate was conducted with...
Certain B-vitamins and vitamin A may be involved in inflammatory pathways associated with homocysteine omega-3 fatty acids. The aims of this study were (i) to determine whether different metabolic profiles Brazilian children adolescents positively or negatively related acids using k-means clustering analysis, (ii) compare nutrient intakes metabolites between the profiles, (iii) evaluate if statistically significant found groups, can predict variation leukotriene A4 hydrolase (LTA4H) levels,...
Fatty acids play a significant role in maintaining cellular and DNA protection we previously found an inverse relationship between blood levels of eicosapentaenoic acid (EPA) docosahexaenoic (DHA) damage. The aim this study was to explore differences proteomic profiles, for 117 pro-inflammatory proteins, two defined groups individuals with different damage EPA DHA levels. Healthy children adolescents (n = 140) aged 9 13 years old urban area Brazil were divided by k-means cluster test into...