A5003874766- Nutritional Studies and Diet
- Nutrition, Genetics, and Disease
- Metabolomics and Mass Spectrometry Studies
- Diet and metabolism studies
- Consumer Attitudes and Food Labeling
- Obesity, Physical Activity, Diet
- Adipose Tissue and Metabolism
- Pancreatic function and diabetes
- Gestational Diabetes Research and Management
- Gut microbiota and health
- Fatty Acid Research and Health
- Muscle metabolism and nutrition
- Birth, Development, and Health
- Nutrition and Health in Aging
- Protein Hydrolysis and Bioactive Peptides
- Diet, Metabolism, and Disease
- Reproductive Biology and Fertility
- Folate and B Vitamins Research
- Metabolism, Diabetes, and Cancer
- Vitamin D Research Studies
- Photosynthetic Processes and Mechanisms
- Advanced Chemical Sensor Technologies
- Hemoglobin structure and function
- Biochemical effects in animals
- Infant Nutrition and Health
Food for Health Ireland
2016-2025
University College Dublin
2016-2025
Teagasc - The Irish Agriculture and Food Development Authority
2021-2024
Bristol Royal Infirmary
2023
Joint Research Center
2022
Public Health England
2022
Federal Office of Public Health
2022
Agriculture and Food
2021
Conway School of Landscape Design
2010-2020
Michigan Medicine
2018
Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have become methods choice to characterize the human metabolome MS-based metabolomics is increasingly used complex metabolic effects nutrients or foods. However progress still hampered by many unsolved problems most notably lack well established standardized procedures, difficulties met in identification metabolites influenced a given nutritional intervention. The purpose this paper review main obstacles...
Metabolomics is the comprehensive study of metabolome, repertoire biochemicals (or small molecules) present in cells, tissues, and body fluids. The metabolism at global or "-omics" level a rapidly growing field that has potential to have profound impact upon medical practice. At center metabolomics, concept person's metabolic state provides close representation individual's overall health status. This reflects what been encoded by genome, modified diet, environmental factors, gut microbiome....
Background: Optimal nutritional choices are linked with better health, but many current interventions to improve diet have limited effect. We tested the hypothesis that providing personalized nutrition (PN) advice based on information individual and lifestyle, phenotype and/or genotype would promote larger, more appropriate, sustained changes in dietary behaviour. Methods: Adults from seven European countries were recruited an internet-delivered intervention (Food4Me) randomized to: (i)...
Abstract The menstrual cycle is an essential life rhythm governed by interacting levels of progesterone, estradiol, follicular stimulating, and luteinizing hormones. To study metabolic changes, biofluids were collected at four timepoints in the from 34 healthy, premenopausal women. Serum hormones, urinary hormone self-reported timing used for a 5-phase classification. Plasma urine analyzed using LC-MS GC-MS metabolomics lipidomics; serum clinical chemistries; plasma B vitamins HPLC-FLD. Of...
Background: Advances in nutritional assessment are continuing to embrace developments computer technology. The online Food4Me food frequency questionnaire (FFQ) was created as an electronic system for the collection of nutrient intake data. To ensure its accuracy assessing both and group intake, further validation against data obtained using a reliable, but independent, instrument reproducibility required. Objective: aim assess validity FFQ 4-day weighed record (WFR). Methods:...
There has been a marked decline in the fertility of dairy cows over past decades, and metabolomic analysis offers potential to investigate underlying causes. Metabolite composition follicular fluid, which presents intrafollicular environment, may be an important factor affecting oocyte maturation subsequent early embryo development. The aim present study was metabolic differences between fluid from dominant follicle lactating heifers using gas chromatography mass spectrometry (GC-MS)-based...
Abstract Background Data from metabolomic studies are typically complex and high-dimensional. Principal component analysis (PCA) is currently the most widely used statistical technique for analyzing data. However, PCA limited by fact that it not based on a model. Results Here, probabilistic principal (PPCA) which addresses some of limitations PCA, reviewed extended. A novel extension PPCA, called covariates (PPCCA), introduced provides flexible approach to jointly model data additional...
Purpose: The primary purpose of this study was to compare the effects two different exercise training programs on executive cognitive functions and functional mobility in older adults. A secondary explore potential mediators function with particular reference physical fitness gains. Methods: sample 42 healthy community dwelling adults aged 65 75 years participated twice weekly for 3 months either: (1) multicomponent training, prioritizing neuromuscular coordination, balance, agility,...