A5039957036- Gut microbiota and health
- Birth, Development, and Health
- Infant Nutrition and Health
- Diet and metabolism studies
- Food composition and properties
- Child Nutrition and Water Access
- Lipid Membrane Structure and Behavior
- Nutritional Studies and Diet
- Probiotics and Fermented Foods
- Nutrition, Genetics, and Disease
- Pediatric health and respiratory diseases
- Breastfeeding Practices and Influences
- Consumer Attitudes and Food Labeling
- Ethics in Clinical Research
- Diabetes Treatment and Management
- SARS-CoV-2 and COVID-19 Research
- Meta-analysis and systematic reviews
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Infection Control and Ventilation
- Health, Environment, Cognitive Aging
- Sphingolipid Metabolism and Signaling
- COVID-19 and Mental Health
Nestlé (Switzerland)
2018-2025
Nestlé (France)
2019-2024
Nestlé (United Kingdom)
2023
Abstract Sphingomyelin (SM) supports brain myelination, a process closely associated with cognitive maturation. The presence of SM in breast milk suggests role infant nutrition; however, little is known about contribution to healthy development. We investigated the link between early life dietary SM, later development and myelination using an exploratory observational study neurotypical children. levels were quantified nutrition products fed first three months myelin content (brain MRI) as...
Emerging science shows that probiotic intake may impact stress and mental health. We investigated the effect of a 6-week intervention with Bifidobacterium longum (BL) NCC3001 (1 × 1010 CFU/daily) on stress-related psychological physiological parameters in 45 healthy adults mild-to-moderate using randomized, placebo-controlled, two-arm, parallel, double-blind design. The main results showed supplementation significantly reduced perceived improved subjective sleep quality score compared to...
Introduction Novel technologies have enabled the decentralization of many aspects clinical trials, but little research has been done on impact these changes participant experience, trial operations, or environment. Methods A fully decentralized conducted in Singapore is used as a case study to evaluate operational outcomes, environmental (via life cycle assessment), and participants experience (qualitative interviews) model compared traditional with in-person visits. Results The achieved...
Micronutrients are in small amounts foods, act concert, and require variable of time to see changes health risk for disease. These first principles incorporated into an intervention study designed develop new experimental strategies setting target recommendations food bioactives populations individuals.
<title>Abstract</title> The gut microbiomes during pregnancy and infancy play a critical role in maternal infant health, yet our understanding of what determines their temporal dynamics, interactions, health impacts remains poor. In this study, we profiled 4,577 longitudinal fecal samples from 714 mother-infant pairs the Dutch birth cohort LLNEXT, 12 weeks to one year postpartum. Hospital records questionnaires were longitudinally evaluated assess 474 clinical, dietary, exposure variables,...
The complexity of the carbohydrate structure is associated with post-prandial glucose response and diverse health benefits. aim this study was to determine whether, thanks usage minimally invasive monitors, it possible evaluate, in a decentralized setup, glycemic (PPGR) α-glucans differing systematically their degree polymerization (DP 3 vs. DP 60) linkage (dextrin dextran). Ten healthy subjects completed double-blind, randomized, crossover trial, testing at home, real life conditions, four...
During the COVID-19 pandemic, many companies implemented working from home to mitigate spread of disease among their employees. Using data Corona Immunitas Nestlé, a seroepidemiological study conducted employees two Nestlé sites in Switzerland, we aimed investigate whether there was difference SARS-CoV-2 infection rates between most time and mobilized workplace equipped with specialized occupational safety unit strict sanitary measures. We also investigated this association modified by...
The Bone And MicroBiOme Onset (BAMBOO) study is an ongoing prospective observational cohort conducted in Tianjin, China, aiming to determine age-appropriate trajectories for microbiome maturation and bone development identify the influence of dietary factors process.
Abstract Background: Early childhood growth and development is critical for long term health. Emerging science spotlights the significance of optimal gut microbiome bone during this period. The aim Bone And MicroBiOme Onset (BAMBOO) study to determine age-appropriate trajectories maturation development, identify influence dietary factors in process. This paper describe rationale design, reports progress. Methods: BAMBOO an ongoing prospective observational cohort conducted Tianjin, China....