Edenil Costa Aguilar

ORCID: 0000-0001-9035-8230
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About
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Research Areas
  • Celiac Disease Research and Management
  • Peroxisome Proliferator-Activated Receptors
  • Antioxidant Activity and Oxidative Stress
  • Microscopic Colitis
  • Adipose Tissue and Metabolism
  • Atherosclerosis and Cardiovascular Diseases
  • Fatty Acid Research and Health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cholesterol and Lipid Metabolism
  • Liver Disease Diagnosis and Treatment
  • Gut microbiota and health
  • Diet, Metabolism, and Disease
  • Nutrition, Genetics, and Disease
  • Birth, Development, and Health
  • Cancer, Hypoxia, and Metabolism
  • Tea Polyphenols and Effects
  • Phytochemistry Medicinal Plant Applications
  • Pharmacological Effects of Natural Compounds
  • Eosinophilic Esophagitis
  • Parasites and Host Interactions
  • Diet and metabolism studies
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Nitric Oxide and Endothelin Effects
  • Viral gastroenteritis research and epidemiology
  • Consumer Attitudes and Food Labeling

Universidade Federal de Minas Gerais
2013-2024

Icahn School of Medicine at Mount Sinai
2024

Laboratoire de Biochimie
2011

Benemérita Universidad Autónoma de Puebla
2000

This study evaluated the relationship between ulcerative colitis and obesity, which are both chronic diseases characterized by inflammation increases in immune cells pro-inflammatory cytokines. Mice with induced 2 cycles of dextran sodium sulfate (DSS) first fourth week experiment were fed a high-fat diet (HFD) to induce obesity 8 weeks. The animals divided into 4 \ groups (control, colitis, HFD + HFD). Obesity alone did not raise histopathology scores, but combination worsened scores colon...

10.1186/1476-511x-10-204 article EN cc-by Lipids in Health and Disease 2011-01-01

Capsaicin, a pungent compound in chili peppers, is described as having potent anti-inflammatory, antioxidant, and antimicrobial properties. It also potential modulator of the immune system intestinal microbiota. Oral or rectal administration capsaicin has been studied to treat prevent colitis. However, those vias are often not well accepted due burning sensation that can cause. Our objective was evaluate whether application skin creams (0.075%) would be effective improving inflammation...

10.1021/acsptsci.4c00207 article EN cc-by ACS Pharmacology & Translational Science 2024-06-12

Pequi is the fruit of Caryocar brasiliense and its oil has a high concentration monounsaturated saturated fatty acids, which are anti- pro-atherogenic agents, respectively, carotenoids, give it antioxidant properties. Our objective was to study effect intake cholesterol-rich diet supplemented with pequi oil, compared same containing soybean on atherosclerosis development, oxidative stress in atherosclerosis-susceptible LDL receptor-deficient mice (LDLr(-/-), C57BL/6-background). Female were...

10.1590/s0100-879x2012007500074 article EN cc-by Brazilian Journal of Medical and Biological Research 2012-05-05

The classical renin-angiotensin system pathway has been recently updated with the identification of additional molecules [such as angiotensin converting enzyme 2, ANG-(1-7), and Mas receptor] that might improve some pathophysiological processes in chronic inflammatory diseases. In present study, we focused on potential protective role receptor activation mouse lipid profile, liver steatosis, atherogenesis. Mas/apolipoprotein E (ApoE)-double-knockout (DKO) mice (based C57BL/6 strain 20 wk...

10.1152/ajpregu.00249.2013 article EN AJP Regulatory Integrative and Comparative Physiology 2013-10-03

ABSTRACT Apolipoprotein E deficient (Apo E−/−) mice are more resistant to the development of obesity compared C57BL/6 wild type mice. They also hold a high basal oxidative status due loss antioxidant action apolipoprotein E. Since is an inducer inflammation, we studied effect high‐fat diet on and stress in Apo E−/− for 9 weeks. The results confirmed that fed increase both body weight adiposity Despite this, presented higher was enhanced by diet. Macrophage infiltration, macrophage forming...

10.1111/j.1740-0929.2011.00982.x article EN Animal Science Journal 2011-12-08

Capsaicin, a bioactive compound found in peppers, is recognized for its anti-inflammatory, antioxidant, and anti-lipidemic properties. This study aimed to evaluate the effects of capsaicin on atherosclerosis progression.

10.3390/nu16183167 article EN Nutrients 2024-09-19

White tea is an unfermented made from young shoots of Camellia sinensis protected sunlight to avoid polyphenol degradation. Although its levels catechins are higher than those green (derived the same plant), there no studies addressing relationship between this and obesity associated with oxidative stress.The objective study was evaluate effect white on complications using a diet induced model. Forty male C57BL/6 mice were fed high-fat induce (Obese group) or supplemented 0.5% extract + WTE)...

10.1590/s0101-20612012005000099 article EN Food Science and Technology 2012-09-04

Abstract Gluten is only partially digested by intestinal enzymes and can generate peptides that alter permeability, facilitating bacterial translocation, thus affecting the immune system. Few studies addressed role of diet with gluten in development colitis. Therefore, we investigate effects wheat gluten-containing on evolution sodium dextran sulphate (DSS)-induced Mice were fed a standard without (colitis group) or 4·5 % + gluten) for 15 d received DSS solution (1·5 %, w/v) instead water...

10.1017/s0007114518003422 article EN British Journal Of Nutrition 2018-12-17

Caryocar brasiliense (popular name pequi) is widely consumed by the population of Brazilian Savannah. This fruit has a high concentration monounsaturated fatty acids that can influence positively lipid profile. In addition, pequi also an important saturated which, in turn, associated with atherosclerosis risk. study aimed to investigate effect pequi-supplemented diet on blood and glucose levels hepatic histology. Female Albino swiss mice were divided into three groups fed standard chow...

10.1590/s0101-20612011000400008 article EN Food Science and Technology 2011-12-01

Background Hookworms infect millions of people worldwide and can cause severe clinical symptoms in their hosts. Prospective cohort studies Brazil show high rates hookworm reinfection malnourished children compared to well-nourished children, despite previous treatment. Additionally, soil-transmitted helminth (STH) infections worsen the nutritional status affected populations. Therefore, this study aims clarify effects host malnutrition during Ancylostoma ceylanicum infection how affects...

10.1371/journal.pntd.0003184 article EN cc-by PLoS neglected tropical diseases 2014-09-25

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic disorder in world. We have seen that gluten intake exacerbated obesity and atherosclerosis apolipoprotein E knockout (ApoE-/-) mice. In this study, we investigated effect of consumption on inflammation oxidative stress mice with NAFLD. Male ApoE-/- were fed a gluten-free (GF-HFD) or gluten-containing (G-HFD) high-fat diet for 10 weeks. Blood, liver, spleen collected to perform analyses. The animals group had increased...

10.1039/d3fo00149k article EN Food & Function 2023-01-01

Food allergy is an abnormal immune response to antigens introduced into the body through food. Its prevalence has increased in developed and developing countries. Natural products are traditionally used alleviate treat diseases, diet can play a role both prevention management of food allergy. The effects capsaicin as anti-oxidant, anticarcinogenic, anti-inflammatory energy expenditure suppression fat accumulation have been demonstrated. This study evaluated effect oral supplementation with on model.

10.1016/j.waojou.2019.100045 article EN cc-by World Allergy Organization Journal 2019-01-01
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