Cândido Celso Coimbra

ORCID: 0000-0001-8981-6724
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About
Contact & Profiles
Research Areas
  • Adipose Tissue and Metabolism
  • Thermoregulation and physiological responses
  • Exercise and Physiological Responses
  • Heart Rate Variability and Autonomic Control
  • Cardiovascular and exercise physiology
  • Circadian rhythm and melatonin
  • Sports Performance and Training
  • Stress Responses and Cortisol
  • Neuroscience of respiration and sleep
  • Muscle metabolism and nutrition
  • Diet and metabolism studies
  • Infrared Thermography in Medicine
  • Regulation of Appetite and Obesity
  • Sports injuries and prevention
  • Dietary Effects on Health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Sleep and Wakefulness Research
  • Neuroendocrine regulation and behavior
  • Cardiovascular Effects of Exercise
  • Pharmacological Effects and Assays
  • Osteoarthritis Treatment and Mechanisms
  • Hypothalamic control of reproductive hormones
  • Growth Hormone and Insulin-like Growth Factors
  • High Altitude and Hypoxia
  • Effects of Vibration on Health

Universidade Federal de Minas Gerais
2016-2025

Universidade Federal dos Vales do Jequitinhonha e Mucuri
2011-2024

Sociedade Brasileira de Cardiologia
2016

Institut des Sciences Biologiques
2009-2015

Czech Academy of Sciences, Institute of Physiology
2010

GTx (United States)
2009

Institute of Molecular Biology and Biophysics
2008

University of Geneva
1989

Thiamine is an important cofactor of metabolic enzymes, and its deficiency leads to cardiovascular dysfunction. First, we characterized the status measuring resting oxygen consumption rate lactate blood concentration after 35 days thiamine (TD). The results pointed a decrease in twofold increase lactate. Confocal microscopy showed that intracellular superoxide (∼40%) H 2 O (2.5 times) contents had been increased. In addition, biochemical activities protein expression SOD, glutathione...

10.1152/ajpheart.00820.2009 article EN AJP Heart and Circulatory Physiology 2010-03-20

This study evaluated the relationship between ulcerative colitis and obesity, which are both chronic diseases characterized by inflammation increases in immune cells pro-inflammatory cytokines. Mice with induced 2 cycles of dextran sodium sulfate (DSS) first fourth week experiment were fed a high-fat diet (HFD) to induce obesity 8 weeks. The animals divided into 4 \ groups (control, colitis, HFD + HFD). Obesity alone did not raise histopathology scores, but combination worsened scores colon...

10.1186/1476-511x-10-204 article EN cc-by Lipids in Health and Disease 2011-01-01

The study objectives were to evaluate the effects of adding whole-body vibration squat training on functional performance and self-report disease in elderly individuals with knee osteoarthritis (OA).This was a prospective, randomized trial which selected variables evaluated at three periods: 3 weeks prior training, immediately prior, after end training.Twenty-three (23) subjects using four tests: Berg Balance Scale (BBS), Timed Get Up Go Test (TGUG), Chair Stand (CST), 6-Minute Walk (6MWT),...

10.1089/acm.2010.0782 article EN The Journal of Alternative and Complementary Medicine 2011-11-17

Intense exercise is a physiological stress capable of inducing the interaction neutrophils with muscle endothelial cells and their transmigration into tissue. Mechanisms driving this inflammatory response are not known. Here, we investigate whether production reactive oxygen species relevant for neutrophil recruitment quadriceps in mice subjected to treadmill fatiguing protocol. Mice exercised until fatigue by running 56.3±6.8 min on an electric treadmill. Skeletal was evaluated intravital...

10.1371/journal.pone.0096464 article EN cc-by PLoS ONE 2014-05-05

Dietary glutamine (Gln) supplementation improves intestinal function in several stressful conditions. Therefore, the present study, effects of dietary Gln on core body temperature ( T ), bacterial translocation (BT) and permeability mice subjected to acute heat stress were evaluated. Male Swiss (4 weeks old) implanted with an abdominal sensor randomly assigned one following groups fed isoenergetic isoproteic diets for 7 d before experimental trials: group standard AIN-93G diet exposed a high...

10.1017/s0007114514002608 article EN British Journal Of Nutrition 2014-10-17

Ramos, GP, Nakamura, FY, Penna, EM, Wilke, CF, Pereira, LA, Loturco, I, Capelli, L, Mahseredjian, F, Silami-Garcia, E, and Coimbra, CC. Activity profiles in U17, U20, senior women's Brazilian national soccer teams during international competitions: are there meaningful differences? J Strength Cond Res 33(12): 3414-3422, 2019-The aim of this study was to compare locomotor activity top-class female players competing at distinct age brackets (under 17 [U17], under [U20], senior). External match...

10.1519/jsc.0000000000002170 article EN The Journal of Strength and Conditioning Research 2017-08-01

This study investigates the potential associations between isokinetic torque ratio of women’s hamstring and quadriceps musculature soccer players’ on-field performance during official games. Data from Brazilian U-20 National Soccer Team (19.22 ± 0.83 years, n = 9) elite (29.17 5.49 6) were analyzed. Isokinetic concentric muscle strength tests at 60°/s conducted bilaterally using a dynamometer. Peak (measured in newton meters) to peak for both legs recorded. During games, total distance...

10.1123/wspaj.2024-0025 article EN Women in Sport and Physical Activity Journal 2025-01-01

Bone loss is common with aging, particularly due to reduced sex hormones, as seen in menopause. While physical training a known non-pharmacological therapy for osteopenia and sarcopenia, few studies compare resistance aerobic protocols, especially systemic inflammatory markers. This study evaluated the effects of on performance, femoral trabecular bone quality (micro-computed tomography), serum markers (IL-1β, IL-6, TNF-α, IL-10) gastrocnemius muscle area ovariectomized (OVX) female mice....

10.1080/13697137.2025.2471059 article EN Climacteric 2025-03-18

The pathogenesis of nonalcoholic fatty liver disease (NAFLD) is not fully understood, and experimental models are an alternative to study this issue. We investigated the effects a simple carbohydrate-rich diet on development obesity-related NAFLD impact physical training metabolic abnormalities associated with disorder. Sixty Wistar rats were randomly separated into control groups, which fed sucrose-enriched (18% carbohydrates) standard diet, respectively. At end each period (5, 10, 20, 30...

10.1155/2016/9127076 article EN cc-by Journal of Diabetes Research 2015-12-14

The understanding of obsesity-related vascular dysfunction remains controversial mainly because the diseases associated with injury. Exercise training is known to prevent dysfunction. Using an obesity model without comorbidities, we aimed at investigating underlying mechanism and how exercise interferes this process.High-sugar diet was used induce in mice. performed 5 days/week. Body weight, energy intake, adipose tissues were assessed; blood metabolic hormonal parameters determined; serum...

10.3389/fphys.2016.00386 article EN cc-by Frontiers in Physiology 2016-09-07

The aim of this study was to determine the match locomotor characteristics a sample U-20 Brazilian female soccer players. Seven international matches were analyzed during 2015 South American Championship, using global positioning technology. During typical match, fullbacks and forwards covered greater distances in high-intensity running sprinting than central defenders midfielders (effect size [ES]=1.42-3.69). In final 15 min game, total distance player load ≈20 35% (ES=0.41-3.86) lower...

10.1055/s-0043-110767 article EN International Journal of Sports Medicine 2017-08-07

What is the central question of this study? The aim was to identify factors predicting body core temperature athletes at end a 10 km self-paced run in hot environment. main finding and its importance? Hyperthermia subjected running depends on several factors, highlighting integrated control during exercise under environmental heat stress. Five seven variables that significantly predicted are not invasive and, therefore, practical for use outside laboratory environment: heart rate, sweat...

10.1113/ep091017 article EN cc-by Experimental Physiology 2023-04-05

The aim of the present study was to evaluate Ca2+ handling and contractility properties cardiomyocytes isolated from rats with high intrinsic aerobic exercise capacity. Standard-performance (SP) high-performance (HP) were categorized a treadmill progressive test according time fatigue (TTF). SP group included TTF between 16.63 46.57 min, HP TTF>46.57 min. Isolated ventricular dissociated hearts rats, intracellular global ([Ca2+]i) transients measured. [Ca2+]i transient peak increased in...

10.1152/japplphysiol.91218.2008 article EN Journal of Applied Physiology 2009-06-05
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