A5076550241- Influenza Virus Research Studies
- Respiratory viral infections research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Urinary Tract Infections Management
- Vaccine Coverage and Hesitancy
- Pneumocystis jirovecii pneumonia detection and treatment
- Nosocomial Infections in ICU
- Long-Term Effects of COVID-19
- Viral Infections and Outbreaks Research
- Immune Response and Inflammation
- Antimicrobial Resistance in Staphylococcus
- Bacterial Infections and Vaccines
- Infective Endocarditis Diagnosis and Management
- Disaster Response and Management
- COVID-19 and Mental Health
- Antibiotic Use and Resistance
- Infection Control and Ventilation
- Viral Infections and Immunology Research
- COVID-19 Pandemic Impacts
- Animal Disease Management and Epidemiology
- Streptococcal Infections and Treatments
Hallym University Kangnam Sacred Heart Hospital
2016-2024
Hallym University
2014-2024
Hallym University Medical Center
2016-2024
Lithuanian University of Health Sciences
2019-2022
Universitair Ziekenhuis Brussel
2019
Office of Infectious Diseases
2015
Chuncheon National Hospital
2015
Korea University
2007-2014
Korea University Medical Center
2013
Due to limited therapeutic options, the spread of extended-spectrum beta-lactamases (ESBLs) have become a major public health concern. We conducted prospective, randomized, open-label comparison efficacy piperacillin-tazobactam (PTZ), cefepime, and ertapenem in febrile nosocomial urinary tract infection with ESBL-producing Escherichia coli (ESBL-EC). This study was at three university hospitals between January 2013 August 2015. Hospitalized adult patients presenting fever were screened for...
OBJECTIVES:Since the report of first confirmed case in Daegu on February 18, 2020, local transmission coronavirus disease 2019 (COVID-19) Korea has continued.In this study, we aimed to identify pattern COVID-19 using mathematical modeling and predict epidemic size timing end spread. METHODS:We modeled outbreak by applying a model that factors behavioral changes.We used Centers for Disease Control Prevention data daily cases country estimate nationwide Daegu/Gyeongbuk area-specific rates as...
To determine the in vitro activities and interactions of imipenem, colistin tigecycline with old antibacterial agents against carbapenem-resistant Acinetobacter baumannii.Forty-three A. baumannii isolates from intensive care unit a university hospital were collected their MICs determined. With eight randomly selected isolates, an time-kill study was performed for evaluation activity colistin, tigecycline, imipenem/sulbactam colistin/rifampicin.The demonstrated bactericidal at concentrations...
Although some intravenous drugs have been used to treat coronavirus disease 2019 (COVID-19), no effective antiviral agents are currently available in the outpatient setting. We aimed evaluate efficacy and adverse events of 14-day ciclesonide treatment vs. standard care for patients with mild-to-moderate COVID-19. A randomized, open-label, multicenter clinical trial inhalers was conducted Patients were enrolled within 3 days diagnosis or 7 from symptom onset randomly assigned receive either...
Despite use of the 13-valent pneumococcal conjugate vaccine (PCV13) and 23-valent polysaccharide (PPSV23) over last decade, disease burden pneumonia is still high. We evaluated field effectiveness PCV13, PPSV23, sequential vaccination against in older adults.This prospective multicenter study was conducted adults aged ≥65 years hospitalized with community-acquired (CAP) between September 2015 August 2017. The case-control test-negative design used to estimate (VE) CAP.Of 1525 cases CAP...
Herpes zoster (HZ) is a prevalent disease characterized by painful rash. A multi‑country study was conducted to elicit public and physician knowledge, attitude, practice (KAP) toward HZ vaccination for the assessment of local factors influencing vaccine perceptions in four Asian-Pacific countries/territories One-to-one qualitative interviews were 2022, among (people aged ≥ 50 years, adults with parents live-vaccinated individuals years Republic Korea, patients; n = 78) physicians (general...
Background During the 2011/2012 winter influenza season in Republic of Korea, A (H3N2) was predominant virus first peak period activity during second half January 2012. On other hand, B March The objectives this study were to compare clinical and epidemiological characteristics patients with laboratory-confirmed or B. Methodology/Principal Findings We analyzed data from 2,129 adult influenza-like illnesses who visited emergency rooms seven university hospitals Korea October 2011 May Of 850...
Etiologies and clinical profiles of acute respiratory viral infections need to be clarified improve preventive therapeutic strategies.A retrospective observational study at a single, university-affiliated center was performed evaluate the infection etiologies in children compared that adults document features common for from July 2009 April 2012.The viruses detected (2,800 total patients) were human rhinovirus (hRV) (31.8%), adenovirus (AdV) (19.2%), syncytial virus (RSV) A (17.4%), RSV B...
Serosurveillance studies reveal the actual disease burden and herd immunity level in population. In Seoul, Korea, a cross-sectional investigation showed 0.07% anti-severe acute respiratory syndrome coronavirus-2 antibody seropositivity among 1,500 outpatients of university hospitals. Low seroprevalence reflects well-implemented social distancing. should be repeated as pandemic progresses.
ABSTRACT The influenza vaccination is known as the most effective method for preventing infection and its complications in elderly. Conventional subunit (Agrippal S1; Novartis), MF59-adjuvanted (Fluad; intradermal (IDflu15; Sanofi Pasteur) vaccines are widely used throughout South Korea. However, few comparative studies evaluating safety immunogenicity of these available. Prior to beginning 2011-2012 season, 335 healthy elderly volunteers randomly received one three seasonal trivalent...
Pneumonia is a leading infectious cause of morbidity and mortality among adults. Pneumococcal pneumonia (PP) the most common vaccine-preventable bacterial etiology pneumonia. In this study, we estimated incidence community-acquired (CAP) pneumococcal diseases Korean adults.Clinical microbiological databases from three hospitals were retrospectively reviewed to determine case fatality rates CAP in adults aged ≥19 years 2011 2014. Incidence CAP, PP invasive (IPD) evaluated based on catchment...
Reliable results regarding serologic positivity for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody before and after AstraZeneca (AZ) vaccination are essential estimating the efficacy of vaccination. We assessed rates associated factors using five SARS-CoV-2 assays. A total 228 paired serum samples (456 samples) were obtained from participants. After baseline sampling, second sampling was conducted between 11 28 days first dose AZ vaccine. Sera tested assays, including...
Background Whether or not a single-dose Ad26.COV2.S prime and boost vaccination induces sufficient immunity is unclear. Concerns about the increased risk of breakthrough infections in Ad26.COV2.S-primed population have also been raised. Methods A prospective cohort study was conducted. Participants included healthy adults who were primed scheduled to receive booster with BNT162b2, mRNA-1273, Ad26.COV2.S. The IgG anti-receptor binding domain (RBD) antibody titers, neutralizing (NAb) titers...
Abstract Background With the global increase in older population, proportion of those receiving care long-term facilities (LTCFs) has also been increasing. We assessed epidemiology, antibiotic susceptibility, and colonization status drug-resistant organisms patients transferred from LTCFs. Methods retrospectively reviewed medical records LTCFs between 2017 2022. The reasons for admission, antimicrobial rates carbapenem-resistant Enterobacterales (CRE), methicillin-resistant Staphylococcus...
Backgrounds: Patients with chronic kidney disease (CKD) are at an increased risk of morbidity and mortality from influenza. However, the immunogenicity influenza vaccine is known to be attenuated in these patients. In this study, MF59-adjuvanted non-adjuvanted trivalent vaccines was compared CKD patients undergoing hemodialysis (HD).Methods: During 2013–2014, 179 HD participated study. The were randomized into either group or immunized respective vaccine. Sera collected prior vaccination 1...
Although the 13-valent pneumococcal conjugate vaccine (PCV13) showed good efficacy against disease in CAPiTA trial, 23-valent polysaccharide vaccination (PPSV23) program has been ongoing for older adults aged ≥ 65 years Korea since May of 2013. This study aimed to evaluate cost-effectiveness current strategy (a single-dose PPSV23 vaccination) compared a PCV13 and sequential PCV13-PPSV23 vaccinations elderly population years.Using Markov model, incremental ratios (ICERs) three strategies were...
ABSTRACT No previous studies have assessed the persistence of immune responses in individuals with diabetes. We conducted this study to evaluate long-term immunogenicity and safety an influenza vaccine type 2 diabetic subjects compared nondiabetic controls. A randomized controlled was at two university hospitals during 2012-2013 season. The a standard-dose trivalent subunit inactivated intramuscular vaccine. Serum hemagglutination-inhibiting (HI) antibodies were measured time vaccination 1...
Abstract Elderly people are at great risk for influenza‐related serious complications. However, influenza vaccine‐induced antibodies believed to decline more rapidly in the elderly. This study was designed evaluate long‐term and cross‐reactive immunogenicity among those aged ≥65 years two seasonal trivalent vaccines during 2009–2010 season. One vaccine had MF59 adjuvant, while other did not contain an adjuvant. Serum hemagglutinin inhibition (HI) titers were determined pre‐vaccination 1 6...
With prolonged life expectancies, mental illness has emerged as a disabling disorder among people with HIV.This study was conducted to assess the prevalence of depression and its risk factors Korean patients HIV infections. Eighty-two HIV-infected completed structured questionnaires including Beck Depression Inventory State-Trait Anxiety Inventory. Subjects were compared those without in terms demographics, comorbidities, CD4 T-cell count, RNA copy numbers, highly active antiretroviral...