- Microbial Metabolic Engineering and Bioproduction
- Genetic and phenotypic traits in livestock
- thermodynamics and calorimetric analyses
- Evolution and Genetic Dynamics
- Viral Infectious Diseases and Gene Expression in Insects
- Metabolomics and Mass Spectrometry Studies
- Virus-based gene therapy research
- Protein Structure and Dynamics
- Bacterial Genetics and Biotechnology
- Aluminum Alloys Composites Properties
- Gene Regulatory Network Analysis
- Image and Video Quality Assessment
- CAR-T cell therapy research
- Genetic Mapping and Diversity in Plants and Animals
- Photodynamic Therapy Research Studies
- Photosynthetic Processes and Mechanisms
- CRISPR and Genetic Engineering
- Computational Drug Discovery Methods
- Enzyme Catalysis and Immobilization
- Antibiotics Pharmacokinetics and Efficacy
- Text and Document Classification Technologies
- Advancements in Battery Materials
- Chronic Kidney Disease and Diabetes
- Advanced ceramic materials synthesis
- Biochemical and biochemical processes
Inner Mongolia University of Science and Technology
2024
Chinese Academy of Sciences
2016-2024
Affiliated Hospital of North Sichuan Medical College
2024
Shanghai Aerospace Automobile Electromechanical (China)
2023-2024
Baotou Medical College
2024
National Institute for Viral Disease Control and Prevention
2024
North China University of Water Resources and Electric Power
2023-2024
Qingdao Institute of Bioenergy and Bioprocess Technology
2023-2024
Northwest A&F University
2022-2023
Qinghai New Energy (China)
2023
Abstract Ferulic acid is a ubiquitous phenolic compound in lignocellulose, which recognized for its role the microbial carbon catabolism and industrial value. However, recalcitrance toxicity poses challenge ferulic acid-to-bioproducts bioconversion. Here, we develop genome editing strategy Pseudomonas putida KT2440 using an integrated CRISPR/Cas9n-λ-Red system with pyrF as selection marker, maintains cell viability genetic stability, increases mutation efficiency, simplifies manipulation....
In this paper, we present a simple but effective method to enhance blind video quality assessment (BVQA) models for social media videos. Motivated by previous researches that leverage pre-trained features extracted from various computer vision as the feature representation BVQA, further explore rich quality-aware image (BIQA) and BVQA auxiliary help model handle complex distortions diverse content of Specifically, use SimpleVQA, consists trainable Swin Transformer-B fixed SlowFast, our base...
Fine-grained IP geolocation plays a critical role in applications such as location-based services and cybersecurity. Most existing fine-grained methods are regression-based; however, due to noise the input data, these typically encounter kilometer-level prediction errors provide incorrect region information for users. To address this issue, paper proposes novel hierarchical multi-label classification framework prediction, named HMCGeo. This treats problem employs residual connection-based...
Achieving superior ductility, microstructure, and strength simultaneously in tailor-welded blanks remains challenging. To address this, pre-aging before friction stir welding was proposed. Systematic studies were conducted on the post-aging of pre-aged 2219 aluminium alloy after welding. Uniaxial tensile tests evaluated ductility at room cryogenic temperatures, along with their mechanical properties artificial aging. Microstructural characterization Vickers hardness measurements elucidated...
Abstract Nonmetal‐dual doped graphene has attracted considerable attention as high‐performance anode material for lithium‐ion batteries (LIBs) due to the synergistic effects of heteroatom dopants. Herein, nitrogen and halogen (including Cl, Br, I) dual‐doped is successfully synthesized by a general wet chemical method lithium storage performance N, Cl codoped LIBs investigated in detail. The heteroatoms introduce abundant defects expand interlayer spacing benefit insertion extraction. When...
Abstract Background The laboratory mouse was domesticated from the wild house mouse. Understanding genetics underlying domestication in mice, especially widely used classical inbred is vital for studies using models. However, genetic mechanism of remains unknown due to lack adequate genomic sequences mice. Results We analyze relationships by whole-genome resequencing 36 mice and strains. All cluster together distinctly wild-derived Using nucleotide diversity analysis, Fst, XP-CLR, we...
Fructose is an important monosaccharide product widely applied in the food, medicine, and chemical industries. Currently, fructose mainly manufactured with plant biomass-sourced polysaccharides through multiple steps of digestion, conversion, separation, purification. The development cyanobacterial metabolic engineering provides attractive alternative route for one-step direct production utilizing carbon dioxide solar energy. In this work, we developed a paradigm chassis cells into efficient...
Abstract Glucosylglycerol (GG) is a natural compatible solute that can be synthesized by many cyanobacteria and few heterotrophic bacteria under high salinity conditions. In cyanobacteria, GG GG-phosphate synthase phosphatase, hydrolase GGHA catalyzes its degradation. (such as some Marinobacter species), fused form of phosphatase present, but the cyanobacteria-like degradation pathway not available. Instead, phosphorylase GGP, which coding gene located adjacent to encodes GG-synthesizing...
The transitional expression and aggregation of amyloid β (Aβ) are the most important causative factors leading to deterioration Alzheimer's disease (AD), a commonly occurring metabolic among older people. Antioxidant agents such as vitamin C (Vc) have shown potential effects against AD aging. We applied an liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method differential metabolites strategy explore disorders Vc restoration in human Aβ transgenic (Punc-54::Aβ1-42)...
Mouse adenoviruses (MAdV) play important roles in studying host–adenovirus interaction. However, easy-to-use reverse genetics systems are still lacking for MAdV. An infectious plasmid pKRMAV1 was constructed by ligating genomic DNA of wild-type MAdV-1 with a PCR product containing backbone through Gibson assembly. A fragment excised from restriction digestion and used to generate intermediate pKMAV1-ER, which contained E3, fiber, E4, E1 regions MAdV-1. CMV promoter-controlled GFP expression...
In recent years, artificial intelligence (AI) driven video generation has garnered significant attention due to advancements in stable diffusion and large language model techniques. Thus, there is a great demand for accurate quality assessment (VQA) models measure the perceptual of AI-generated content (AIGC) videos as well optimize However, assessing AIGC quite challenging highly complex distortions they exhibit (e.g., unnatural action, irrational objects, etc.). Therefore, this paper, we...
AI-driven video generation techniques have made significant progress in recent years. However, AI-generated videos (AGVs) involving human activities often exhibit substantial visual and semantic distortions, hindering the practical application of technologies real-world scenarios. To address this challenge, we conduct a pioneering study on activity AGV quality assessment, focusing evaluation identification distortions. First, construct AI-Generated Human Video Quality Assessment...
The processes involved in cell growth are extremely complicated even for a single organism such as Escherichia coli, while the relationship between rate and size is simple. We aimed to reveal systematic link them from aspect of genome-scale metabolic network. Since reflects rates bacteria relates phospholipid synthesis, part bacterial networks, we calculated length cardiolipin synthesis rate, where reaction able represent metabolism coli exponential phase. Combined with flux balance...
Currently, the single-point incremental forming process often faces issues such as insufficient formability of sheet metal and low strength formed parts. To address this problem, study proposes a pre-aged hardening (PH-SPIF) that offers several notable benefits, including shortened procedures, reduced energy consumption, increased limits while maintaining high mechanical properties geometric accuracy in components. investigate limits, an Al-Mg-Si alloy was used to form different wall angles...
The aim of this study was to locate SSTR5 polymorphisms and evaluate their association with growth traits in Hulun Buir sheep. followed up 884 sheep from birth 16 months age, which were born the same pasture year, a consistent grazing management strategy maintained. weight (BRW) recorded at birth, body (BW), height (BH), length (BL), chest circumference (ChC), depth (ChD), width (ChW), hip (HW), cannon (CaC) measured 4 9 age. BW, BH, BL, ChD, HW, CaC also Based on traits, 233 selected as...
Oxidative hair dyes consist of two components (I and II) that are mixed before use. Aromatic amines in component I their reaction with hydrogen peroxide after mixing them II have been primary concern. In addition, vitro genotoxicity assays still required for the approval final products oxidative China, substance dye causes high rate positive results tests, especially Ames test, has not fully elucidated. this study, we analyzed formulation 55 different from 7 color series performed tests...
Genomic imprinting is an epigenetic phenomenon mainly occurs in endosperm of flowering plants. Genome-wide identification imprinted genes have been completed several dicot Cruciferous plant and monocot crops.Here, we analyzed global patterns allelic gene expression developing sunflower which belongs to the composite family. Totally, 691 loci candidates were identified 12 day-after-pollination including 79 maternally expressed (MEG) 596 paternally (PEG), 6 noncoding RNAs (MNC) 10 (PNC). And a...