A5056918405- Algal biology and biofuel production
- Photosynthetic Processes and Mechanisms
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Microbial Metabolic Engineering and Bioproduction
- Microbial Natural Products and Biosynthesis
- Enzyme Catalysis and Immobilization
- Biofuel production and bioconversion
- Biocrusts and Microbial Ecology
- Microbial Community Ecology and Physiology
- Microbial Metabolism and Applications
- Fungal Biology and Applications
- Plant biochemistry and biosynthesis
- Geology and Paleoclimatology Research
- Enzyme Production and Characterization
- Genomics and Phylogenetic Studies
- Cancer Research and Treatments
- Enzyme Structure and Function
- Microbial Metabolites in Food Biotechnology
- CRISPR and Genetic Engineering
- Pleistocene-Era Hominins and Archaeology
- RNA and protein synthesis mechanisms
- Bacterial Genetics and Biotechnology
- Plant Gene Expression Analysis
- Genetic Mapping and Diversity in Plants and Animals
Chinese Academy of Sciences
2016-2025
Qingdao Institute of Bioenergy and Bioprocess Technology
2016-2025
Qingdao National Laboratory for Marine Science and Technology
2017-2025
University of Chinese Academy of Sciences
2008-2025
Lanzhou University of Technology
2016-2025
Dalian National Laboratory for Clean Energy
2019-2025
Qinghai New Energy (China)
2021-2025
Shanghai Jiao Tong University
2010-2024
Ministry of Agriculture and Rural Affairs
2024
Guizhou Academy of Agricultural Sciences
2023-2024
Two atmospheric circulation systems, the mid-latitude Westerlies and Asian summer monsoon (ASM), play key roles in northern-hemisphere climatic changes. However, variability of Asia their relationship to ASM remain unclear. Here, we present longest highest-resolution drill core from Lake Qinghai on northeastern Tibetan Plateau (TP), which uniquely records both since 32 ka, reflecting interplay these two systems. These document anti-phase for glacial-interglacial glacial millennial...
The rapidly growing demand for energy and the environmental concerns about carbon dioxide emissions make development of renewable biofuels more attractive. Tremendous academic industrial efforts have been made to produce bioethanol, which is one major type biofuel. current production bioethanol limited commercialization because issues with food competition (from food-based biomass) or cost effectiveness lignocellulose-based biomass). In this report we applied a consolidated bioprocessing...
Cyanobacteria can utilize solar energy and convert carbon dioxide into biofuel molecules in one single biological system. Synechocystis sp. PCC 6803 is a model cyanobacterium for basic applied research. Alkanes are the major constituents of gasoline, diesel jet fuels. A two-step alkane biosynthetic pathway was identified cyanobacteria recently. It opens door to achieve photosynthetic production alka(e)nes with high efficiency by genetically engineering cyanobacteria.A series PCC6803 mutant...
Cytochrome P450 OleTJE from Jeotgalicoccus sp. ATCC 8456, a new member of the CYP152 peroxygenase family, was recently found to catalyze unusual decarboxylation long-chain fatty acids form α-alkenes using H2O2 as sole electron and oxygen donor. Because aliphatic are important chemicals that can be used biofuels replace fossil fuels, or for making lubricants, polymers detergents, studies on acid decarboxylase significant may lead commercial production biogenic in future, which renewable more...
Developing efficient CO2 utilization technologies can alleviate the urgent pressure on energy and environment. Moreover, these are crucial for achieving goal of net zero emissions. Microalgae photoautotrophic microorganisms that main sources primary productivity in biosphere. Cyanobacteria, only prokaryotic microalgae, have also been considered as promising chassis photosynthetic biosynthesis, directly converting solar into various bio-based products. This technological route is called...
Photosynthesis can be impaired by combined high light and temperature (HLHT) stress. Obtaining HLHT tolerant photoautotrophs is laborious time-consuming, in most cases the underlying molecular mechanisms remain unclear. Here, we increase mutation rates of cyanobacterium Synechococcus elongatus PCC 7942 three orders magnitude through combinatory perturbations genetic fidelity machinery cultivation environment. Utilizing hypermutation system, isolate mutants with improved tolerance identify...
Abstract Flavonoids are important plant natural products with variable structures and bioactivities. All known flavonoids generated under the catalysis of a type III polyketide synthase (PKS) followed by chalcone isomerase (CHI) flavone (FNS). In this study, biosynthetic gene cluster chlorflavonin, fungal flavonoid acetolactate inhibitory activity, was discovered using self‐resistance‐gene‐directed strategy. A novel pathway in fungi revealed. core nonribosomal peptide synthetase‐polyketide...
Itaconic acid, which has been declared to be one of the most promising and flexible building blocks, is currently used as monomer or co-monomer in polymer industry, produced commercially by Aspergillus terreus. However, production level itaconic acid hasn’t improved past 40 years, mutagenesis still main strategy improve itaconate productivity. The genetic engineering approach applied industrial A. terreus strains increase production. In this study, genes closely related production, including...
Fatty alcohols are widely used in industrial chemicals. The biosynthetic pathways for fatty diverse and existing nature. They display a high capacity to produce by the metabolic engineering of different microbe hosts. Direct recycling carbon dioxide can be achieved introducing alcohol-producing pathway into photosynthetic cyanobacteria. According our precious reports, relatively low yield was obtained genetically engineered cyanobacterium Synechocystis sp. PCC 6803. production 6803 improved...
Sucrose and glycogen syntheses in cyanobacteria share the common precursor glucose-1-phosphate. It is generally assumed that lowering synthesis could drive more carbon toward sucrose can be induced by salt stress among cyanobacteria. By using a theophylline-dependent riboswitch system, expression of glgC, key gene synthesis, was downregulated quantitative manner sucrose-secreting strain Synechococcus elongatus PCC 7942. We observed stepwise suppression limited rather than stimulated...
Abstract Calcium/calmodulin-dependent protein serine kinase (CASK) is a key player in vesicle transport and release neurons. However, its precise role, particularly nonneuronal systems, incompletely understood. We report that CASK functions as an important regulator of insulin secretion. depletion mouse islets/β cells substantially reduces secretion docking/fusion. forms ternary complex with Mint1 Munc18-1, this event regulated by glucose stimulation β cells. The crystal structure the...
Abstract Marine microbial ecosystems can be viewed as a huge ocean-battery charged by solar energy. It provides model for fabricating bio-solar cell, bioelectrochemical system that converts light into electricity. Here, we fabricate cell consisting of four-species community mimicking the ecological structure marine ecosystems. We demonstrate such primary producer, degrader, and ultimate consumers is essential achieving high power density stability. Furthermore, assembled spatial-temporally...
Glucose is the most abundant monosaccharide, serving as an essential energy source for cells in all domains of life and important feedstock biorefinery industry. The plant-biomass-sugar route dominates current glucose supply, while direct conversion carbon dioxide into through photosynthesis not well studied. Here, we show that potential Synechococcus elongatus PCC 7942 photosynthetic production can be unlocked by preventing native glucokinase activity. Knocking out two genes causes...
Zhu, C., Ma, Yu, S.‐Y., Tang, L., Zhang, W. & Lu, X. 2009: A detailed pollen record of vegetation and climate changes in Central China during the past 16 000 years. Boreas , 10.1111/j.1502‐3885.2009.00098.x. ISSN 0300‐9483. Detailed analyses, along with magnetic loss‐on‐ignition (LOI) measurements, were conducted on a 3 m long peat sequence recovered from Dajiuhu Basin, Shennongjia Mountains China. Ten AMS 14 C dates provide firm age control this terms governed essentially by rise fall...
Biodiesel is a renewable alternative to petroleum diesel fuel that can contribute carbon dioxide emission reduction and energy supply. composed of fatty acid alkyl esters, including methyl esters (FAMEs) ethyl (FAEEs), currently produced through the transesterification reaction methanol (or ethanol) triacylglycerols (TAGs). TAGs are mainly obtained from oilseed plants microalgae. A sustainable supply major bottleneck for current biodiesel production. Here we report de novo biosynthesis FAEEs...