A5101505602- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Acupuncture Treatment Research Studies
- Ophthalmology and Visual Impairment Studies
- Visual perception and processing mechanisms
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Corneal Surgery and Treatments
- Ophthalmology and Eye Disorders
- Advanced MRI Techniques and Applications
- Neural dynamics and brain function
- Renal cell carcinoma treatment
- Inflammatory Biomarkers in Disease Prognosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Lung Cancer Research Studies
- Vestibular and auditory disorders
- MRI in cancer diagnosis
- Corneal surgery and disorders
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Retinal Diseases and Treatments
- Neurological Disease Mechanisms and Treatments
- Magnetism in coordination complexes
- Neonatal and fetal brain pathology
- Optical Imaging and Spectroscopy Techniques
Affiliated Hospital of Southwest Medical University
2024
Fudan University
2023-2024
The University of Texas Southwestern Medical Center
2015-2023
Tianjin University of Traditional Chinese Medicine
2017-2023
Chinese People's Liberation Army
2023
First Affiliated Hospital of Nanchang University
2016-2022
Nanchang University
2016-2022
Zhejiang University
2022
State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
2022
University of South China
2021
Abstract: Docetaxel is an adjuvant chemotherapy drug widely used to treat multiple solid tumors; however, its toxicity and side effects limit clinical efficacy. Herein, docetaxel-loaded lipid nanoparticles (DSNs) were developed reduce systemic of docetaxel while still keeping anticancer activity. To evaluate activity toxicity, understand the molecular mechanisms DSNs, different cellular, molecular, whole genome transcription analysis approaches utilized. The DSNs showed lower cytotoxicity...
Previous studies have demonstrated that strabismus or amblyopia can result in markedly brain function and anatomical alterations. However, the differences spontaneous activities of with (SA) patients still remain unclear. This current study intended to use amplitude low-frequency fluctuation (ALFF) technique investigate intrinsic activity changes SA subjects.A total 16 (6 males 10 females) healthy controls (HCs; 6 similarly matched age, gender, education status were recruited examined...
Previous studies have demonstrated that strabismus or amblyopia can result in marked brain function and anatomical alterations. However, differences spontaneous activity (SA) patients as compared with control individuals remain unclear. The present study aimed to analyze the potential changes SA their association behavioral performance. In total, 16 (10 women 6 men) healthy controls (HCs; men 10 women) matched age sex were recruited. All subjects examined resting‑state functional magnetic...
To evaluate the differences in functional connectivity (FC) of primary visual cortex (V1) between youth comitant exotropia (CE) patients and health subjects using resting magnetic resonance imaging (fMRI) data.Totally, 32 CEs (25 males 7 females) healthy control (HCs) were enrolled study underwent MRI scanning. Two-sample t-test was used to examine FC maps CE HCs.The showed significantly less left brodmann area (BA17) lingual gyrus/cerebellum posterior lobe, right middle occipital gyrus,...
Abstract Objective Neuroimaging studies have shown that patients with pain‐related conditions altered neuronal activity and structural functions. The purpose of this study was to investigate whether classical trigeminal neuralgia ( CTN ) exhibit changes in corresponding via analysis regional homogeneity (ReHo). Methods A total 28 presenting sore eyes (12 men 16 women) were matched healthy controls women). All participants underwent functional magnetic resonance imaging fMRI ). This ReHo...
Objective: Breast cancer is the most common primary lesion resulting in intraocular metastasis (IOM). In this study, we investigated differences between breast patients with and without IOM, clarified risk factors for IOM cancer. Methods: A total of 2,381 were included study from January 2005 to December 2017. The chi-square test Student's t-test applied evaluate non-IOM (NIOM) groups. Risk calculated using binary logistic regression analysis. Receiver operating curve (ROC) analysis was used...
Objective: Many previous studies have reported that pain symptoms can lead to significant brain function and anatomical changes, whereas the intrinsic activity changes in acute eye (EP) patients remain unknown. Using amplitude of low-frequency fluctuation (ALFF) method, this study aimed evaluate spontaneous alterations their relationships with clinical features EP patients. Participants methods: A total 20 (15 males 5 females) healthy controls (HCs; 15 closely matched age, sex, education...
Background Neuroimaging studies revealed that trigeminal neuralgia was related to alternations in brain anatomical function and regional function. However, the functional characteristics of network organization whole is unknown. Purpose The aim present study analyze potential brain-activity changes their relationships with clinical features patients via voxel-wise degree centrality method. Material Methods This involved a total 28 (12 men, 16 women) healthy controls matched sex, age,...
// Yi Shao 1, * , Jing Bao Xin Huang 2 Fu-Qing Zhou 3 Lei Ye 1 You-Lan Min Lin Yang Zubin Sethi 4 Qing Yuan and Qiong Department of Ophthalmology, The First Affiliated Hospital Nanchang University, 330006, Jiangxi, China People's Hubei Province, Wuhan 430060, Hubei, Radiology, University Miami, Florida 33146, USA These authors contributed equally to this work Correspondence to: Zhou, email: 375135747@qq.com Keywords: monocular blindness; voxel-mirrored homotopic connectivity; resting state;...
This study investigated the changes in interhemispheric functional connectivity (FC) of whole brain open globe injury (OGI) patients, using voxel-mirrored homotopic (VMHC), and their relationships with clinical features. Totally, 16 male 2 female acute OGI patients 18 sex, age, education-matched healthy volunteers were enrolled study. All subjects scanned through magnetic resonance imaging (fMRI). Receiver operating characteristic (ROC) curves analyses had been used to identify VMHC these...
Leaf photosynthesis largely determines the daughter corm yields in vegetative growth for saffron (Crocus sativus L.). Most of previous researches focus on spectral response various species, but research leaves at different leaf ages is lacking. In this study, action spectrum based photosynthetic photon flux density (PPFD) and irradiance were distinguished interpreted. The optical properties performances were, respectively, investigated two ages, dependent customized narrow-band LED...
Salvianolate lyophilized injection (SLI) has been clinically used in China for the treatment of acutely cerebral infarction. Clinical and experimental studies have shown that Diabetes mellitus (DM) not only increases risk ischemic stroke recurrence but also leads to poor outcomes fatality rates after stroke. Our previous study proved SLI can reduce infarct volume type 1 diabetic rats. The aim is explore mechanism on outcome (T1DM) rats.Type diabetes rats model was induced male Wistar by...
Alkali burn is one of the main causes corneal injury. The inflammation and neovascularization caused by alkali burns aggravate damage, resulting in loss vision. aim present study was to evaluate efficacy xanthatin treatment burn‑induced neovascularization. A CCK‑8 assay used detect effects different concentrations on proliferation human umbilical vein endothelial cells (HUVECs). migration HUVECs ability lumen formation were examined using a scratch test assay, respectively. total 60...
Previous neuroimaging studies have demonstrated that pain-related diseases are associated with brain function and anatomical abnormalities, whereas altered synchronous neural activity in acute eye pain (EP) patients has not been investigated. The purpose of this study was to explore whether or changes were measured the regional homogeneity (ReHo) method EP patients.A total 20 (15 males 5 females) healthy controls (HCs) consisting 15 age-, sex-, education-matched females, respectively,...
Abstract Present indoor cultivation of saffron ( Crocus sativus L.) only depends on artificial planting experience, so that flower number and stigma yield are seriously affected in case cloudy or rainy days temperature changes. In this study, a luminaire was used at 10-h photoperiod combined 450 nm blue LEDs with 660 broad-band red LEDs, which respectively had full width half maximum (FWHM) 15 85 nm, ratio blue: red: far-red light = 20%: 62%: 18%. The influence total daily integral (TDLI)...
Purpose: The present study was attempted to compare the differences in gray matter volume (GMV) between acute eye pain (EP) patients and healthy controls (HCs) using voxel-based morphometry (VBM), explore relationship with clinical features behavioral performance. Methods: A total of 24 (17 males, 7 females) EP age-, sex-, education-matched HCs were recruited from Ophthalmology Department First Affiliated Hospital Nanchang University. Functional magnetic resonance imaging (fMRI) scans...
Abstract Background The prognostic significance of preoperative plasma fibrinogen in patients with operable gastric cancer remains under debate. This study aimed to elucidate the value underwent gastrectomy. Methods A total 4351 collected from three comprehensive medical centers were retrospectively evaluated. Patients categorized by minimum P using X‐tile, while baseline confounders for was balanced through propensity score matching (PSM). relationships between and other clinicopathologic...