- Corneal Surgery and Treatments
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Functional Brain Connectivity Studies
- Ocular Diseases and Behçet’s Syndrome
- Ocular Disorders and Treatments
- Visual perception and processing mechanisms
- Retinal Diseases and Treatments
- S100 Proteins and Annexins
- Advanced Neuroimaging Techniques and Applications
- Cerebral Venous Sinus Thrombosis
- HER2/EGFR in Cancer Research
- Pharmacological Effects of Natural Compounds
- PARP inhibition in cancer therapy
- Consumer Packaging Perceptions and Trends
- Click Chemistry and Applications
- Digital Media and Visual Art
- Wound Healing and Treatments
- Advanced Decision-Making Techniques
- Cancer Mechanisms and Therapy
- Protein Degradation and Inhibitors
- Bryophyte Studies and Records
- Vestibular and auditory disorders
- Intraocular Surgery and Lenses
- Ocular Infections and Treatments
Huaqiao University
2023
Xiamen University
2023
First Affiliated Hospital of Nanchang University
2013-2022
Nanchang University
2014-2022
Nankai University
2022
Jilin College of the Arts
2011
Modern Electron (United States)
2004
Purpose: This study investigated the role of S100 calcium binding protein A4 (S100A4) in corneal wound healing and underlying mechanism S100A4-mediated PI3K/Akt/mammalian target rapamycin (mTOR) pathway. Methods: The rabbit alkali burn model was established vivo. S100A4 expression, healing, inflammation, autophagy cornea after were detected. NaOH-treated stromal cells (rCSCs) transfected with overexpressed or silencing to examine effect on vitro. cell viability, proliferation, migration,...
To investigate the potential regional homogeneity (ReHo) brain activity changes in patients with corneal ulcer (CU) and their possible relationship clinical symptoms.Forty CU (26 men 14 women), 40 healthy controls (HCs) women) closely matched age, sex, weight underwent resting-state functional MRI scans, respectively. The ReHo method was applied to evaluate synchronous neural changes. Receiver operating characteristic curve (ROC curve) used show high test-retest stability degree of...
Previous neuroimaging studies have demonstrated that pain-related diseases are associated with brain function and anatomical abnormalities, whereas altered synchronous neural activity in acute eye pain (EP) patients has not been investigated. The purpose of this study was to explore whether or changes were measured the regional homogeneity (ReHo) method EP patients.A total 20 (15 males 5 females) healthy controls (HCs) consisting 15 age-, sex-, education-matched females, respectively,...
Abstract Background Previous studies have demonstrated that strabismus amblyopia can result in markedly brain function alterations. However, the differences spontaneous activities of (SA) patients still remain unclear. Therefore, current study intended to employthe voxel-mirrored homotopic connectivity (VMHC) method investigate intrinsic activity changes SA patients. Purpose To cerebral hemispheric functional connections with and their relationship clinical manifestations using VMHC method....
Polycyclic aromatic hydrocarbons (PAHs), as the main components of petroleum (PHCs), are carcinogenic organic pollutants that occur widely in atmospheric environment with increasing concentration. Moreover, PAHs widespread all over world due to their high volatility and long-range transport potential. The monitoring is often limited by working conditions, especially around oil field operation areas other industrial areas. Mosses (Bryophyta), most sensitive atmosphere pollution indicators,...
To investigate the effects of catalpol on corneal neovascularization (CNV) and associated inflammation, eye drops (5 mM or PBS) were administered four times daily to alkali‑burn rat models CNV inflammation. Clinical evaluations degree inflammation performed days 0, 4, 7, 10 14 under slit lamp microscopy. Eyes collected day prepared for hematoxylin eosin, immunofluorescence staining; cell apoptosis was investigated via terminal deoxynucleotidyl transferase‑mediated nick end labeling (TUNEL)...
Objectives To determine the typical corneal changes in pure microphthalmia using a topography system and identify characteristics that may assist early diagnosis. Methods Patients with healthy control subjects underwent analysis (Orbscan IIZ® Corneal Topography System; Bausch Lomb, Bridgewater, NJ, USA) to degree of astigmatism (mean A), simulation (sim mean keratometry K), simulated irregularities 3 - 5-mm zone, thickness nine distinct regions. Results ( n = 12) had significantly higher K,...
We studied the clinical efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema. From May 2009 to April 2013, 78 patients seeking treatment for edema First Affiliated Hospital Nanchang University were enrolled this study. Patients randomly divided into two groups: i) The experimental group (n=39) and control (n=39). treated (Avastin®) laser, those exclusively laser. Therapeutic effects compared, postoperative adverse reactions caused by both methods compared....
To investigate the efficiency of Spanishneedles Herb eye drops in treating perimenopausal xerophthalmia rabbits.Totally 36 rabbits (36 right eyes) were ovariectomized, and 2 months later divided into three groups: experimental group (group A, n = 12) given drops, control B, PBS model C, no drug. The Schirmer I test (SIT), fluorescent (FL), total tear protein, diastase activity, lactoferrin lysozyme contents confocal scanning microscopy performed at before treatment 1 w, mo, mo after...
To investigate the efficacy and safety of Honghua preserved amniotic membrane (AM) for preventing scar formation filtering bleb in a rabbit model glaucoma trabeculectomy surgery.Totally 36 rabbits (36 eyes) were randomly divided into 3 groups: experimental group (ocular combination with AM transplantation), control surgery implantation), blank (single trabeculectomy). Clinical observations [including intraocular pressure (IOP), blebs complications], Masson-Trichrome staining, real-time...
Objective To investigate therapeutic efficiency of Pranoprofen capsule on middle and severe xerophthalmia chronic graft versus host disease (cGVHD) after hematopoietic stem cell transplantation (HSCT).Methods A prospective random controlled study.Totally sixteen patients diagnosed cGVHD HSCT from March,01 2007 to July,01 2012 were divided into two groups:Pranoprofen group (group A) control (Vitamin C capsule,group B),eight cases in each group.All groups had been added with Forte eye drops...
Abstract Purpose To investigate the retinal vascular network alterations in eyes of patients with pterygium. Method 18 left from female pterygium and healthy control subjects were enrolled. Optical coherence tomography angiography (OCTA) images generated superficial layer (SRL) deeper (DRL) macular retina for each eye. The microvascular (MIR) macrovascular (MAR) densities calculated MIR, MAR, total MIR (TMI) density was compared groups. Results In group, SRL, SMIR (superficial MIR), SR, IR,...
Abstract Purpose To investigate the retinal vascular network alterations in eyes of patients with pterygium. Method 18 left from female pterygium and 18left 18female healthy control subjectswere enrolled.Optical coherence tomography angiography(OCTA) images were generated superficial retinallayer (SRL) deeper layer (DRL) macular retina for each eye. The microvascular(MIR) macrovascular (MAR) densities calculated MIR, MAR, total MIR (TMI) density was compared healthycontrol groups. Results In...
Abstract BACKGROUND AND PURPOSE This study investigated changes in brain structural connectivity network and "small-world" topology children with strabismus amblyopia by resting-state functional magnetic resonance imaging (rs-fMRI)and graph theory. MATERIALS METHODS A total of 18 (SA) matched healthy control (HC) subjects were enrolled. We use rs-fMRI theory to preprocess the date, Difference parameters area under integral curve between two groups evaluated 2 sample t-test. Network-based...