A5042985738- Viral gastroenteritis research and epidemiology
- Vibrio bacteria research studies
- Marine Toxins and Detection Methods
- Viral Infections and Immunology Research
- Hepatitis Viruses Studies and Epidemiology
- Environmental Toxicology and Ecotoxicology
- Phytoplasmas and Hemiptera pathogens
- Aquaculture disease management and microbiota
- Environmental Chemistry and Analysis
- Hepatitis B Virus Studies
- Migration, Health and Trauma
- Animal Virus Infections Studies
- Family Support in Illness
- Child Nutrition and Water Access
- HIV/AIDS Impact and Responses
- Animal Ecology and Behavior Studies
- Viral Infections and Outbreaks Research
- Adolescent and Pediatric Healthcare
- Parasites and Host Interactions
- Cocoa and Sweet Potato Agronomy
- Travel-related health issues
- Virus-based gene therapy research
- Marine Sponges and Natural Products
- Bacterial Infections and Vaccines
- Salmonella and Campylobacter epidemiology
Istituto Zooprofilattico Sperimentale della Sardegna
2012-2024
Public Health Institute
2018-2021
University of Sassari
2018-2019
Regione Autonoma della Sardegna
2018
Diarrhoetic shellfish poisoning (DSP), an alimentary intoxication known to lead intestinal symptoms, and caused by toxins produced some dinoflagellates (including several Dinophysis), represents a serious threat public health. The aim of this paper was provide information about the occurrence abundance potentially toxic harmful algal species causing DSP, associated concentration okadaic acid (OA) toxins. departing assumption that in study area there increase presence both Dinophysis OA its...
Edible lamellibranch molluscs can be involved in foodborne disease and infections of varying severity. They are filter feeding animals able to retain concentrate their organism bacteria, parasites, viruses biotoxins marine algae present external environment. Major shellfish harvesting relaying areas from different Sardinia region were defined studied by analysing physicochemical parameters the water levels Escherichia coli (E. coli), Norovirus (NoVs) genogroup I (NoVGI), NoVs II (NoVGII)...
Control of vaccine preventable diseases, while constituting a priority European health policies, is challenged by migrations from countries with suboptimal levels immunization coverage. We report here two different types vaccination campaign strategy in one the bigger Italian asylum seekers' centres. The service staff local national institute came monthly during first three years observation, last year, vaccinations were offered directly upon arrival migrants centre.we performed descriptive...
Introduction: North Africa has become a key migratory hub where large number of migrants attempt the journey by sea from Libyan coastline to south Europe. In this humanitarian disaster scenario, Mediterranean route been one most used illegal boats.
 Methodology: report, state physical and psychological health cluster Eritrean migrants, escaped Libya rescued in Sea after shipwreck, was described epidemiological, clinical laboratory investigations.
 Results: Data suggest that despite...
Childhood neurodevelopmental disorders (NDDs), including specific learning (SLD), attention deficit/hyperactivity disorder (ADHD) and autism spectrum (ASD), are pathogenically linked to familial autoimmunity maternal immune-mediated diseases during pregnancy.We studied MS as a potential risk factor for NDDs occurrence in offspring.MS control mothers were subjected questionnaires ascertain NDD diagnosis their progeny the of both autoimmune neurodevelopment families. Suspected cases evaluated...
This work reports the first communication relating to presence of yessotoxins in Mytilus galloprovincialis from coastal mussel farms (Sardinia, western Mediterranean) detected during 2008 and 2013 through a monitoring programme. The paper emphasizes how changes both yessotoxin permitted limits used methods, established by legislation, have influenced interpretation obtained results. Consequently, samples that resulted negative would been positive until August September up now, were nowadays,...
Xylella fastidiosa, a bacterial species infecting broad range plants, includes five subspecies, multiplex, pauca, mulberry and sandyi. In Europe, was isolated in olive trees southern Italy (Apulia region) during the year 2013. The aim of present study to apply phylogenetic evolutionary analysis trace possible origin way entrance fastidiosa Italy. All genomes available for spp were downloaded from NCBI. A phylogeographic performed using BEAST. X. strains belonging subsp. pauca sandyi have...
Despite a significant decrease in acute hepatitis A the last 2 decades Italy, outbreaks were observed occurring mostly southern Italy. In this study, Bayesian phylogenetic analysis was used to analyze origin of these epidemics. With aim, 5 different data sets virus sequences built perform genotyping by neighbor-joining method estimate evolutionary rates using Markov chain Monte Carlo approach and investigate demographic history independent runs enforcing both strict relaxed clock. The...
The aim of the present study was to evaluate Vibrio parahaemolyticus occurrences in bivalve molluscs harvested from Sardinian coastal environments between 2013 and 2015. prevalence pathogenic V. isolates is based on detection two major virulence genes thermostable direct hemolysin (tdh) thermolabile (trh) To assess changes 2011 2018 molluscs, we compared our results with those previous investigations. In total, 2,933 samples were collected: 1,079 2013, 1,288 2014, 566 mean shellfish 3.5%...
Introduction: We describe an outbreak of hepatitis A among men who have sex with (MSM) which evolved in Sassari (Italy), between January 2017 and December 2018, close to a contextual large concurrent reported Europe recently, Italy.
 Methodology: HAV RNA detection molecular characterization was performed from serum samples and/or stool by RT - PCR VP1/2A junction region that ranges nt. 2,873 3,376. The phylogenetic correlation the circulating strains assessed sequencing method according...
African swine fever virus (ASFV) causes a devastating disease affecting domestic and wild pigs. ASF was first introduced in Sardinia 1978 until 2019 only genotype I isolates were identified. A remarkable genetic stability of Sardinian ASFV described, nevertheless two boar with sustained genomic deletion (4342 base pairs) identified (7303WB/19, 7212WB/19). In this study, we therefore performed vitro experiments monocyte-derived macrophages (moMФ) to unravel the phenotypic characteristics...
Objective: To evaluate the evolution of pathogen Mayaro virus, causing fever (a mosquito-borne disease) and to perform selective pressure analysis homology modelling. Methods: Nine different datasets were built, one for each protein (from C non-structural 4) last complete genome. Selective modelling analyses applied. Results: Two main clades (A B) pointed in maximum likelihood tree. The clade A included five Brazilian sequences sampled from 1955 2015. sequence 2014 significantly clustered...
Transplanted patients are particularly exposed to a major risk of infectious diseases due prolonged immunosuppressive treatment. Over the last decade, growing migration flows and transplant tourism have led increasing infections caused by geographically restricted organisms. Malaria is an unusual event in organ recipients than can be acquired primarily or reactivation following immunosuppression, transfusion blood products through transplanted organ. We report rare case Plasmodium falciparum...
In Sardinia (Italy), bivalve molluscs production plays an important role in the trade balance. Diarrhoetic shellfish poisoning (DSP), intoxication caused by ingestion of that have accumulated high levels Okadaic acid (OA), may represent a serious risk for public health and remarkable economic loss producers. Aim this work was to improve knowledge about repeatability OA accumulation phenomena various seasons trying understand whether or not there trend. Also, interaction between toxic algae...
Noroviruses (NoVs), known as Norwalk-Like Viruses (NLV) or Small-Round-Structured-Viruses (SRVS), are among the most frequent causes of acute viral gastroenteritis in human beings, often associated with food poisoning, if raw poorly cooked bivalve molluscs (mussels, clams and oysters) ingested. In compliance EU regulations, safety these products is evaluated according to bacteriological paramenters (Salmonella E.coli) provided for by Regulation (EC) No. 2073/2005, biotoxicological...
Introduction: Salivirus (SalV) represents an emerging problem in public health especially during the recent years. In this study, Bayesian evolutionary history and spread of virus through different countries have been reported.
 Methodology: a database 81 sequences SalV structural VP1 fragment were downloaded from GenBank, aligned manually edited by Bioedit Software. ModelTest v. 3.7 software was used to estimate simplest model fitting sequence dataset. A Maximum-Likelihood tree has...
Several planktonic dinoflagellates can produce lipophilic phycotoxins that represent a significant threat to public health as well shellfish and fish farming. Poisoning related some of these toxins is categorised diarrhetic poisoning. We analysed 975 samples from Tortolì in the central-eastern region Sardinia (Italy) January 2016 March 2020, investigate prevalence different marine biotoxins mollusc bivalves. The results highlighted predominant presence belonging okadaic acid group all with...