A5010225402- HIV/AIDS drug development and treatment
- Plant-based Medicinal Research
- HIV Research and Treatment
- HIV-related health complications and treatments
- Traditional Chinese Medicine Analysis
- Membrane Separation Technologies
- Asthma and respiratory diseases
- Neurological Disease Mechanisms and Treatments
- Membrane-based Ion Separation Techniques
- Pharmacological Effects and Toxicity Studies
- Genomics, phytochemicals, and oxidative stress
- Nanopore and Nanochannel Transport Studies
- Drug-Induced Hepatotoxicity and Protection
- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Nephrotoxicity and Medicinal Plants
- Rheumatoid Arthritis Research and Therapies
- Phytochemistry and Biological Activities
- Dermatology and Skin Diseases
- Coal and Its By-products
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Extraction and Separation Processes
- Heavy metals in environment
- HIV/AIDS Research and Interventions
- Diet, Metabolism, and Disease
Nanjing University of Chinese Medicine
2021-2023
First People's Hospital of Chongqing
2023
Chongqing Public Health Medical Center
2018-2020
Chengdu University of Traditional Chinese Medicine
2016
Traditional Chinese medicine (TCM) is an important part of culture and the pharmaceutical industry. The adoption stricter requirements for quality medicines has resulted in loss conformity some traditional techniques used to prepare TCMs modern methods. TCM industry begun seek out novel methods improve product increase economic efficiency. Membrane technology efficient, energy saving, environmentally friendly. It widely food processing, desalination, wastewater treatment, medical also been...
Purpose: To determine the heavy metal content of Chinese prickly ash (CPA) produced in various areas China.Methods: CPA samples collected from different production China were subjected to microwave digestion, and contents copper (Cu), nickel (Ni), chromium (Cr), lead (Pb), cadmium (Cd), arsenic (As), mercury (Hg), tin (Sn), antimony (Sb) determined by inductively coupled plasma-mass spectrometry (ICP-MS).Results: Heavy levels followed order: Cu (3.29-24.17 mg/kg) > Cr (0.04-7.33 Ni...
The present study investigated the effect of immersion in excipient lime water on toxic component lectin protein and explained scientific connotation detoxication during processing Pinelliae Rhizoma Praeparatum. Western blot was used to investigate effects with different pH(pH 10, 11, 12.4), saturated sodium hydroxide, bicarbonate solution content protein. compositions supernatant precipitate after immersing pH were determined by SDS-PAGE method combined silver staining technique....
Purpose: To determine the molecular mechanism involved in anti-migraine effect of Asari Radix et Rhizoma (ARR) using network pharmacology.
 Methods: The compounds present ARR were identified through information retrieval from literature and public databases, screened based on absorption, distribution, metabolism, excretion toxicity. Target genes related to selected migraine or predicted databases. Hub against analysis interactions overlapping between target genes, STRING database. Gene...
This study investigated the anti-ascites effect of total saponins Phytolaccae Radix(PRTS) and mechanism.H22 cell suspension was used(ip) to induce ascites in ICR male mice, model mice were randomized into group, positive drug group(furosemide, 6 mg·kg~(-1)), extract Radix(PRTE) PRTS(1.29 g·kg~(-1)).Another 10 selected as blank group.Mice group given(ig) normal saline containing 0.5% CMC-Na, those PRTE PRTS received(ig) corresponding doses drugs, once a day, for 8 consecutive days.The volume,...
The present study aims to investigate the correlation between irritant toxicity variation and lectin content during processing of Pinelliae Rhizoma products explore feasibility Western blot as a method for detection lectin. We processed Praeparatum Cum Alumine, Praeparatum, Praeparatumcum Zingibere et Alumine different degrees then analyzed their via Draize rabbit eye test. was employed determine in with methods. analyzed. Different decoction pieces were collected determination content....
To determine the content of endogenous toxic substance Pinellia ternata lectin(PTL) protein in Pinelliae Rhizoma and related processed products, this study prepared specific monoclonal antibodies against PTL by hybridoma cell technology, established a quantitative double-antibody sandwich enzyme linked immunosorbent assay(ELISA) for antigen. The detection conditions were 2.5 μg·mL~(-1) working concentration captured antibody 1∶450 dilution multiple detected antibody. coating condition was...
Purpose: To conduct a systematic analysis on data from randomized controlled trials (RCTs) different doses of guselkumab, and provide high-quality evidence for its use in the treatment patients with moderate-to-severe plaque psoriasis (PsO).
 Methods: Related studies were searched using online search engines including MEDLINE, PubMed, central registry Cochrane January 2001 to October 2017. Only randomized, placebo-controlled, double-blind clinical involving guselkumab- placebo-treated...