A5101471783- Cancer Risks and Factors
- Breast Cancer Treatment Studies
- Cancer-related molecular mechanisms research
- Adipose Tissue and Metabolism
- Metabolism, Diabetes, and Cancer
- Cancer, Lipids, and Metabolism
- Cancer Genomics and Diagnostics
- Estrogen and related hormone effects
- MicroRNA in disease regulation
- Protein Tyrosine Phosphatases
- Cancer Immunotherapy and Biomarkers
- Genetic factors in colorectal cancer
- Dietary Effects on Health
- Endometrial and Cervical Cancer Treatments
- Cancer-related Molecular Pathways
- HER2/EGFR in Cancer Research
- Cancer, Hypoxia, and Metabolism
- Circular RNAs in diseases
- Cytokine Signaling Pathways and Interactions
- Metastasis and carcinoma case studies
- Extracellular vesicles in disease
- Cancer Treatment and Pharmacology
- Exercise and Physiological Responses
- RNA regulation and disease
- Galectins and Cancer Biology
Renmin Hospital of Wuhan University
2011-2025
Wuhan University
2011-2025
The aim of this study was to evaluate the outcomes patients with inflammatory breast cancer (IBC), emphasis on role molecular subtypes and radiotherapy.A retrospective cohort investigate overall survival (OS) cancer-specific mortality (BCSM) in IBC conducted using data obtained by Surveillance, Epidemiology, End Results (SEER) program from 2010-2013. Cox multivariate regression used calculate adjusted Hazard Ratios (aHR).403 were eligible for study. Patients group hormone receptors...
Tamoxifen and anastrozole are widely used as adjuvant treatment for early stage breast cancer, but their hepatotoxicity is not fully defined. We aimed to compare of with tamoxifen in the setting postmenopausal cancer patients. Three hundred fifty-three Chinese women hormone receptor-positive were randomized or after optimal primary therapy. The end-point was fatty liver disease, defined a liver-spleen ratio <0.9 determined using computed tomography scan. secondary end-points included...
The objective of this study was to investigate the clinical pathological characteristics breast cancer (BC) patients with secondary diabetes after systemic therapy without preexisting diabetes. A total 1434 BC received and were analyzed retrospectively. Fasting plasma glucose (FPG) levels monitored prior treatments, during course therapy, at follow-up visits. Cox regression models used estimate associations between cause-specific hazard developing Among patients, 151 had type 2 Of remaining...
Breast cancer is widespread in females. The role of circular RNA (circRNA) breast has aroused much attention. However, the function several circRNAs remain unclear. aim our study was to determine circ_0001955 cancer. Quantitative real-time PCR (qPCR) and western blot employed for expression analysis circ_0001955, miR-1299 glucose transporter 1 (GLUT1). Cell functions including proliferation, apoptosis, migration, invasion angiogenesis, were assessed using EdU, flow cytometry, transwell tube...
// Qi Wu 1 , Juanjuan Li Si Sun 2 Shan Zhu Chuang Chen Juan 3 Qian Liu Wen Wei and Shengrong Department of Breast Thyroid Surgery, Renmin Hospital Wuhan University, Wuhan, Hubei, P. R. China Clinical Laboratory, Pathology, Correspondence to: Sun, email: Keywords : breast carcinoma in situ, tumor subtype, treatment, outcomes Received September 14, 2016 Accepted November 23, Published December 02, Abstract Background & Aims: To evaluate the clinical presentation, treatment outcome patients...
Objective Whether a first-degree family history of others cancers (FHOC) than breast or ovarian cancer (BOC) is associated with prognosis remains unknown. Thus, the aim present study was to clarify this issue. Methods Women who were diagnosed invasive at Renmin Hospital Wuhan University from 2010 2013 included in study. The demographic and clinicopathological characteristics these patients extracted. FHOC considered positive for any patient had relative been other BOC. Disease-free survival...
Abstract Background Luminal A breast cancer has the best prognosis of all malignant types. In clinical practice, some patients with luminal present small tumors (usually <20 mm) but lymph node metastases or even distant organ metastasis. Owing to their insensitivity chemotherapy and lack conclusive evidence, there is a significant gap in research on high invasiveness. This study aimed identify genes that drive invasiveness explore underlying mechanisms. Methods this study, we first...
Abstract Background: Emerging evidence supports the pivotal roles of adipocytes in breast cancer progression. Beige/brown adipose tissue that activates thermogenesis is suggested to contribute hypermetabolic state. However, mediators and mechanisms remain unclear. Methods: Survival probabilities for recurrence-free survival (RFS) 106 patients were estimated using Kaplan-Meier method based on immunohistochemistry results several biomarkers. Biochemical studies performed characterize novel...
Background: Emerging evidence supports the pivotal roles of adipocytes in breast cancer progression. Beige/brown adipose tissue that activates thermogenesis is suggested to contribute hypermetabolic state. However, mediators and mechanisms remain unclear.Methods: Survival probabilities for recurrence-free survival (RFS) 106 patients were estimated using Kaplan-Meier method based on immunohistochemistry results several biomarkers. Biochemical studies performed characterize novel interrelation...