A5056477467- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Esophageal Cancer Research and Treatment
- Pancreatic and Hepatic Oncology Research
- Metastasis and carcinoma case studies
- Pancreatitis Pathology and Treatment
- Celiac Disease Research and Management
- Colorectal Cancer Screening and Detection
- Neuroendocrine Tumor Research Advances
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Vascular Malformations and Hemangiomas
- Microscopic Colitis
- Organ Transplantation Techniques and Outcomes
- Amyloidosis: Diagnosis, Treatment, Outcomes
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Gastroesophageal reflux and treatments
- COVID-19 Clinical Research Studies
- Liver Disease and Transplantation
- Veterinary medicine and infectious diseases
Pontificia Universidad Católica de Chile
2016-2025
Chilean Air Force
2022-2023
ORCID
2021
St. Michael's Hospital
2014-2019
University of Toronto
2014-2019
Landscape Research Group
2018
Hospital Clínico de la Universidad Católica
2017
Universidad del Desarrollo
2012-2014
Clínica Alemana
2014
Apolipoprotein E type 4 allele (apoE epsilon4) is associated with Alzheimer's disease (AD) in the late-onset familial form and sporadic cases, but age-associated risk a randomly sampled elderly population not established. We examined association of apoE epsilon4 AD other dementias (mainly multi-infarct or dementia following stroke) 1,030 persons aged 71 to 100 years population-based Framingham Study cohort. Kaplan-Meier survival analysis revealed that 55% epsilon4/epsilon4 homozygotes...
In recent years there has been a growing body of evidence on water-assisted colonoscopy (WAC). Water exchange (WE) colonoscopy, one the WAC techniques, demonstrated higher intubation rate, adenoma detection rate (ADR), and reduced patient discomfort compared to gas insufflation colonoscopy. our clinical practice, we have observed increased mucus production in rectosigmoid segments during withdrawal when techniques are used with water infusion saline infusion. This white, opaque often...
Background and study aims: Medical professional liability (MPL) is a significant concern for gastrointestinal physicians, yet there are limited data available from Latin America. We aimed to assess frequency of complaints lawsuits related digestive endoscopy among endoscopists in Chile identify associated factors. Methods: An online survey collected sociodemographic data, information about unit characteristics, MPL-related experiences. Invitations were sent 525 between August September 2022....
Abstract Drug-induced esophageal ulcers constitute an acquired chemical injury to the mucosa, most frequently associated with tetracyclines, particularly doxycycline. We report a case of "kissing ulcers" diagnosed through esophagogastroduodenoscopy in young woman undergoing doxycycline treatment for rosacea. The pathogenesis is linked drug-specific factors, such as caustic effects, hyperosmolar properties, and prolonged mucosal contact medication, addition patient-specific risks, including...
Introducción: El cáncer gástrico (CG) es la primera causa de muerte oncológica en Chile. Desde 2006 autoridad sanitaria recomienda endoscopía digestiva alta (EDA) a población sintomática ≥40 años. En 2010 se estimó una cobertura EDA durante el último año este grupo 14%. Objetivo: Describir para cribado del CG Chile partir Encuesta Nacional Salud (ENS) 2016-17. Materiales y métodos: La ENS 2016- 17 realizó 6.233 encuestas adultos sobre presencia epigastralgia persistente, posible hemorragia...
To optimize diagnosis and treatment guidelines for this geographic region, a panel of gastroenterologists, epidemiologists, basic scientists carried out structured evaluation available literature.
The management of ampullary lesions has shifted from surgical approach to endoscopic resection. Previous reports were limited by small numbers patients and short follow-up. aim this study is describe short- long-term outcomes in a large cohort undergoing ampullectomy.
Helicobacter pylori infection in symptomatic patients with benign gastroduodenal diseases.Analysis of 5.664 cases Infection (H.pylori) is highly prevalent Chile, but there are no systematic studies upper gastrointestinal symptoms.Aim: To determine the prevalence H. infection, according to age, gender and endoscopic pathology a large sample patients.Methods: We studied 7,893 submitted endoscopy between July 1996 December 2003 context screening program gastric cancer high risk population.H....
Background. The plasminogen activator inhibitor type-1 (PAI-1) has been implicated in the regulation of fibrinolysis and extracellular matrix components. single base pair guanine insertion/deletion polymorphism (4G/5G) within promoter region PAI-1 gene influences synthesis may modulate hepatic fibrogenesis. Aim. To evaluate influence serum levels 4G/5G on risk liver fibrosis associated to non-alcoholic fatty disease (NAFLD) morbidly obese patients. Material methods. Case-control study 50...
Autoimmune gastritis (AIG) is associated with nutritional deficiencies, autoimmune diseases, and gastric malignancies. The aims of the study were to test hypothesis that mucocutaneous (MC) manifestations occur more often in patients vs without AIG delineate patterns MC AIG.A single-center, prospective 2:1 case-control was conducted. Cases diagnosis based on consistent serologic histologic findings. Controls had a normal biopsy. independently evaluated by 3 experienced dermatologists. We...
Acute pulmonary edema caused by thiazides is uncommon and of difficult diagnosis. It considered an idiosyncratic reaction the physiopathology or cardiac function changes are not well known. We report a 60 year-old female with thiazide induced acute who was followed serial measurements type B n-terminal natriuretic peptide fraction as marker for dysfunction. There significant elevation peptide, associated to evidences ventricular Its normalization paralleled resolution clinical picture.
A national online survey applied to patients with celiac disease in ChileBackground: Celiac (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten genetically susceptible individuals.Its prevalence Europe and USA 0.5 1%.Aim: To analyze epidemiological aspects degree compliance gluten-free diet (GFD) among Chilean individuals CD.Material Methods: Subjects confi rmed or suspected CD were invited answer published on web at www.fundacionconvivir.cl.The answers reinforced a...
Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disease, induced by food allergens, clinically characterized symptoms of esophageal dysfunction. Pathologically there predominant eosinophilic inflammation. This disease relatively new, and its definitions have evolved over time. Its prevalence incidence are increasing causes clinical problems both in children adults. include impaction, dysphagia, that resemble gastroesophageal reflux, abdominal pain, vomiting. It can also...