A5100356349- Porphyrin and Phthalocyanine Chemistry
- Ionic liquids properties and applications
- COVID-19 and Mental Health
- DNA and Nucleic Acid Chemistry
- Inorganic and Organometallic Chemistry
- X-ray Diffraction in Crystallography
- Advanced biosensing and bioanalysis techniques
- Crystallization and Solubility Studies
- Blind Source Separation Techniques
- Metal-Catalyzed Oxygenation Mechanisms
- Metal complexes synthesis and properties
- Carbohydrate Chemistry and Synthesis
- Photochemistry and Electron Transfer Studies
- Electrochemical Analysis and Applications
- Health and Wellbeing Research
- Chemical Synthesis and Reactions
- Asymmetric Synthesis and Catalysis
- Health and Well-being Studies
- Porphyrin Metabolism and Disorders
- Sulfur-Based Synthesis Techniques
- Molecular Sensors and Ion Detection
- Semiconductor materials and devices
- HIV/AIDS drug development and treatment
- Consumer Market Behavior and Pricing
- Surface Chemistry and Catalysis
Saitama University
2025
Wuhan University
2006-2024
Sichuan University
2015-2024
West China Hospital of Sichuan University
2024
Dalian Minzu University
2010-2024
Beijing Polytechnic
2024
Wuhan Technical College of Communications
2023
Fujian Agriculture and Forestry University
2023
Hunan Normal University
2023
Tongji Hospital
2022
China has been severely affected by coronavirus disease 2019 (COVID-19) since December 2019. Military healthcare workers in have experienced many pressures when combating COVID-19. This study aimed to investigate the current psychological status and associated risk factors among military workers.We collected data from 194 three inpatient wards two specialized COVID-19 hospitals using a web-based cross-sectional survey. The survey covered demographic information, patient health...
The self-assembly of 2,7-bis(10-ethoxycarbonyl-decyloxy)-9-fluorenone (BEF) has been investigated by scanning tunneling microscopy at the liquid/solid interface. coexistence and reversible transformation linear structure cyclic network were observed. Solvents with different polarity had little effect on BEF HOPG surface. observed structural was found to be driven voltage pulses applied STM tips. influence dipole–dipole interactions van der Waals (vdWs) packing patterns scrutinized comparing...
Challenges for stereoselective glycosylation of deoxy sugars are notorious in carbohydrate chemistry. We herein report a novel strategy the construction less investigated β-glycosidic bonds 3,5-trans-3-amino-2,3,6-trideoxy (3,5-trans-3-ADSs), which constitute core structure several biologically important antibiotics. Current protocol leverages C-3 axial sulfonamide group 3,5-trans-3-ADSs as hydrogen-bond (H-bond) donor and repurposes substoichiometric phosphine oxide an exogenous...
Herein, we reported on a highly efficient glycosylation reaction comprising two chronological meticulously designed catalytic cycles: (1) rhodium-catalyzed formation of sulfonium ylide and (2) Brønsted acid-catalyzed ion. This protocol highlighted an effective robust tactic to prepare glycosyl ion from precursor amenable for glycosylation.
Anti-inflammatory approaches are emerging as a new strategy for the treatment of depressive disorders. Ginsenoside Rb1 (GRb1), major component Panax ginseng, can inhibit inflammatory cascade and alleviate depressive-like behaviors. Microglia promote or adult hippocampal neurogenesis according to their functional phenotypes. Here, we examine whether GRb1 may exert antidepressant effects by promoting pro-neurogenic phenotype microglia thereby increasing neurogenesis.The licensed imipramine...
Unauthorized unmanned aerial vehicles (UAVs) pose threats to public safety and individual privacy. Traditional object-detection approaches often fall short during their application in anti-UAV technologies. To address this issue, we propose the YOLOv7-GS model, which is designed specifically for identification of small UAVs complex low-altitude environments. This research primarily aims improve model’s detection capabilities backgrounds. Enhancements were applied YOLOv7-tiny including...
A deoxyribozyme that hydrolyzes DNA phosphodiester linkages with a requirement for both Zn2+ and Mn2+ is switched by only two nucleotide mutations to require alone, demonstrating DNA-catalyzed hydrolysis can be achieved using one metal ion cofactor.
We recently reported that a DNA catalyst (deoxyribozyme) can site-specifically hydrolyze on the minutes time scale. Sequence specificity is provided by Watson-Crick base pairing between substrate and two oligonucleotide binding arms flank 40-nt catalytic region of deoxyribozyme. The from our recent in vitro selection effort, 10MD5, cleave single-stranded sequence with aid Zn 2+ Mn cofactors, as long cleavage site encompasses four particular nucleotides ATG^T. Thus, 10MD5 only 1 out every 256...
Functional nucleic acids are DNA and RNA aptamers that bind targets, or they deoxyribozymes ribozymes have catalytic activity. These functional sequences can be identified from random-sequence pools by in vitro selection, which requires choosing the length of random region. Shorter regions allow more complete coverage sequence space but may not permit structural complexity necessary for binding catalysis. In contrast, longer sampled incompletely adoption complicated structures enable...
A water‐soluble cationic gallium corrole, 5,10,15‐tris( N ‐methyl‐4‐pyridyl)corrolatogallium(III) ( 3 ), was prepared and characterized. The photocytotoxicity of investigated using Hep G2 cancer cell line. Upon treatment with corrole irradiation, fragmentation tumor nuclei observed, which led to apoptosis. Flow cytometric analysis clearly showed the efficient induction apoptotic death, exhibited high towards cells (IC 50 = 60 nM). Furthermore, binding behavior c‐MYC G‐quadruplex DNA, a...
Abstract Background: Current replacement procedures for stenosis or occluded arteries using prosthetic grafts have serious limitations in clinical applications, particularly, endothelialization of the luminal surface is a long-standing unresolved problem. Method: We produced cell-based hybrid vascular graft bioink engulfing adipose-derived mesenchymal stromal cells (ADSCs) and 3D bioprinting process lining ADSCs on GORE-Tex grafts. The was implanted as an interposition conduit to replace...
We recently reported the identification by in vitro selection of 10MD5, a deoxyribozyme that requires both Mn2+ and Zn2+ to hydrolyze single-stranded DNA substrate with formation 5′-phosphate 3′-hydroxyl termini. cleavage 10MD5 proceeds kobs = 2.7 h−1 rate enhancement 1012 over uncatalyzed P−O hydrolysis reaction. has very sharp pH optimum near 7.5, greatly reduced yield when is changed only 0.1 unit either direction. Here we have optimized reselection (in evolution), leading variants...
Kernel approximation using randomized feature maps has recently gained a lot of interest. In this work, we identify that previous approaches for polynomial kernel create are rank deficient, and therefore do not utilize the capacity projected space effectively. To address challenge, propose compact random (CRAFTMaps) to approximate kernels more concisely accurately. We prove error bounds CRAFTMaps demonstrating their superior reconstruction performance compared schemes. show how structured...