Paul Simusika

ORCID: 0000-0001-5755-6163
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About
Contact & Profiles
Research Areas
  • Influenza Virus Research Studies
  • Data-Driven Disease Surveillance
  • Respiratory viral infections research
  • SARS-CoV-2 and COVID-19 Research
  • Pneumonia and Respiratory Infections
  • Viral Infections and Outbreaks Research
  • Animal Virus Infections Studies
  • COVID-19 Clinical Research Studies
  • Healthcare cost, quality, practices
  • Quality and Safety in Healthcare
  • SARS-CoV-2 detection and testing
  • Congenital Diaphragmatic Hernia Studies
  • Hepatitis Viruses Studies and Epidemiology
  • Viral Infections and Vectors
  • Viral gastroenteritis research and epidemiology
  • COVID-19 epidemiological studies
  • Health Systems, Economic Evaluations, Quality of Life

University Teaching Hospital
2015-2024

Tohoku University
2024

Lusaka Apex Medical University
2023

Copperbelt University
2021

University of Zambia
2015-2020

Ministry of Health
2020

National Influenza Center
2019

Morbidity and mortality from respiratory infections are higher in resource-limited countries than developed countries, but limited studies have been conducted settings to examine pathogens patients with acute infections. Influenza surveillance has Zambia since 2008; however, only 4.3% of enrolled 2011-2012 were positive for influenza. Therefore, we examined non-influenza children severe illness (SARI) Zambia, estimate the scope disease burden determine commonly-identified pathogens.

10.1186/s12879-015-0779-1 article EN cc-by BMC Infectious Diseases 2015-02-11

Background Estimates of influenza‐associated hospitalization are limited in low‐ and middle‐income countries, especially Africa. Objective To estimate the national number severe acute respiratory illness ( SARI ) Zambia. Methods We conducted active prospective hospital‐based surveillance for at University Teaching Hospital UTH situated Lusaka Province during 2011‐2014. Upper tract samples were tested influenza virus using a reverse transcriptase polymerase chain reaction assay. estimated...

10.1111/irv.12492 article EN cc-by Influenza and Other Respiratory Viruses 2017-12-15

Abstract Background Influenza surveillance helps time prevention and control interventions especially where complex seasonal patterns exist. We assessed influenza sustainability in Africa activity varies external funds for have decreased. Methods surveyed African Network Surveillance Epidemiology ( ANISE) countries about 2011‐2017 system characteristics. Data were summarized with descriptive statistics analyzed univariate multivariable analyses to quantify sustained or expanded capacity...

10.1111/irv.12818 article EN cc-by Influenza and Other Respiratory Viruses 2020-11-04

Annual outbreaks of human respiratory syncytial virus (HRSV) are caused by newly introduced and locally persistent strains. During the COVID-19 pandemic, global local circulation HRSV significantly decreased. This study was conducted to characterize in 2018-2022 analyze impact on evolution HRSV.

10.1016/j.ijregi.2024.03.009 article EN cc-by-nc-nd IJID Regions 2024-03-22

Abstract Background Over the past decade, influenza surveillance has been established in several African countries including Zambia. However, information on data quality and reliability of systems Africa are limited. Such would enable to assess performance their systems, identify shortfalls for improvement provide evidence policy making public health interventions. Methods We used Centers Disease Control Prevention guidelines evaluate system (ISS) Zambia during 2011–2017 using 9 attributes:...

10.1186/s12913-019-4884-5 article EN cc-by BMC Health Services Research 2020-01-13

The coronavirus disease 2019 (COVID-19) which was first reported in Wuhan City, China, has spread to many countries worldwide. It declared a global pandemic by the World Health Organisation (WHO) on 11th March, 2020. As of 12th January, 2021, total 89,707,115 cases and 1,940,352 deaths had been globally, while 28,596 471 Zambia.

10.11604/pamj.2021.38.290.27836 article EN cc-by Pan African Medical Journal 2021-01-01

Background:The emergency of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) variants has led to COVID-19 worldwide with substantial social and economic consequences.SARS CoV-2 S-glycoproteins are involved in viral entry human cells.They naturally the main target host immune responses, most vaccine designs based on them.SARS-CoV-2 categorized as interest (VOI) or concern (VOC) because they deadly highly transmissible, causing illness by overcoming system.Material Methods: The...

10.21608/mid.2023.229457.1592 article EN cc-by Microbes and Infectious Diseases /Microbes and Infectious Diseases 2023-09-09

The occurrence of rotavirus (RV) infection among vaccinated children in high-burden settings poses a threat to further disease burden reduction. Genetically altered viruses have the potential evade both natural and vaccine-induced immune responses, leading diarrheal diseases children. Studies characterizing RV strains responsible for breakthrough infections resource-limited countries where RV-associated are endemic limited. We aimed characterize detected fully residing Zambia using...

10.3390/vaccines11121759 article EN cc-by Vaccines 2023-11-26

Abstract Background Over the past decade, influenza surveillance has been established in several African countries including Zambia. However, information on data quality and reliability of systems Africa are limited. Such would enable to assess performance their systems, identify shortfalls for improvement provide evidence policy making public health interventions. Methods We used Centers Disease Control Prevention guidelines evaluate system (ISS) Zambia during 2011-2017 using 9 attributes:...

10.21203/rs.2.16794/v3 preprint EN cc-by Research Square (Research Square) 2019-12-31

Abstract Background Over the past decade, influenza surveillance has been established in several African countries including Zambia. However, information on data quality and reliability of systems Africa are limited. Such would enable to assess performance their systems, identify shortfalls for improvement provide evidence policy making public health interventions. Methods We used Centers Disease Control Prevention guidelines evaluate system (ISS) Zambia during 2011-2017 using 9 attributes:...

10.21203/rs.2.16794/v2 preprint EN cc-by Research Square (Research Square) 2019-12-19

Abstract Background Over the past decade, influenza surveillance has been established in several African countries including Zambia. However, information on data quality and reliability of systems Africa are limited. Such would enable to assess performance their systems, identify shortfalls for improvement provide evidence policy making public health interventions. Methods We used Centers Disease Control Prevention guidelines evaluate system (ISS) Zambia during 2011-2017 using 9 attributes:...

10.21203/rs.2.16794/v1 preprint EN cc-by Research Square (Research Square) 2019-11-05
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