A5031794132- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Mosquito-borne diseases and control
- Vector-borne infectious diseases
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Rabies epidemiology and control
- Viral Infections and Immunology Research
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Resistance in Bacteria
- Mycobacterium research and diagnosis
- Virology and Viral Diseases
- Tuberculosis Research and Epidemiology
- Trypanosoma species research and implications
- Microbial infections and disease research
- Viral Infections and Outbreaks Research
- COVID-19 Clinical Research Studies
- Animal Virus Infections Studies
- Fire effects on ecosystems
- SARS-CoV-2 detection and testing
- Poxvirus research and outbreaks
- Respiratory viral infections research
- Salmonella and Campylobacter epidemiology
- COVID-19 epidemiological studies
- T-cell and Retrovirus Studies
Ministry of Agriculture and Livestock
2014-2025
Hokkaido University
2019-2023
University of Zambia
2020-2022
Africa Centres for Disease Control and Prevention
2022
University of Edinburgh
2020-2022
Golden Valley Agricultural Research Trust
2020-2022
The University of Tokyo
2022
Global Virus Network
2022
National Center for Global Health and Medicine
2022
Centers for Disease Control and Prevention
2020
Increased antimicrobial resistance (AMR) among bacteria underscores the need to strengthen AMR surveillance and promote data-based prescribing. To evaluate trends associations between usage (AMU) AMR, we explored a dataset of 34,672 bacterial isolates collected 2015 2020 from clinical samples at University Teaching Hospital (UTH) in Lusaka, Zambia. The most frequently isolated species were Escherichia coli (4,986/34,672; 14.4%), Staphylococcus aureus (3,941/34,672; 11.4%), Klebsiella...
SARS-CoV-2 uses its spike protein to enter target cells. The is cleaved by a host protease, and this event facilitates viral entry broadens cell tropism.
The inappropriate use of antibiotics in hospitals contributes to the development and spread antimicrobial resistance (AMR). This study evaluated prevalence antibiotic adherence World Health Organization (WHO) Access, Watch Reserve (AWaRe) classification across 16 Zambia.
Background: Shigella species are the leading cause of human shigellosis. In Zambia, more than 30% children experiencing diarrhea infected with species. The increasing resistance to recommended therapy is great concern. Therefore, this study investigated antibiotic profiles and phenotypic genotypic characteristics isolates at largest referral hospital in Zambia. Methodology: Of forty-eight archived presumptive isolates, thirty-two were serologically confirmed subjected antimicrobial...
During 2013–2015, several and severe outbreaks of African swine fever (ASF) affected domestic pigs in six provinces Zambia. Genetic characterization ASF viruses (ASFVs) using standardized genotyping procedures revealed that genotypes I, II XIV were associated with these outbreaks. Molecular epidemiological data suggest genotype ASFV (Georgia 2007/1-like) detected Northern Province Zambia may have been introduced from neighbouring Tanzania. Also, a virus Eastern showed p54 phylogenetic...
The emergence of pre-extensively drug-resistant tuberculosis (pre-XDR-TB) is a threat to TB control programs in developing countries such as Zambia. Studies Zambia have applied molecular techniques understand drug-resistance-associated mutations, circulating lineages and transmission patterns multi-drug-resistant (MDR) Mycobacterium tuberculosis. However, none has reported genotypes mutations associated with pre-XDR TB. This study characterized 63 M. strains from the University Teaching...
Multidrug-resistant (MDR) Escherichia coli in food animals such as chickens is an emerging public health concern Zambia. Additionally, the country's high demand for poultry products necessitates further investigation into link between and human MDR E. coli. Twenty cefotaxime-resistant isolates collected from Lusaka, Zambia, were screened multidrug resistance sequenced on MiSeq MinION platforms. Genomes assembled de novo compared with 36 previously reported inpatients at University Teaching...
Escherichia coli (E. coli), a major foodborne disease-causing pathogen found in raw cow milk, has even far more reaching public health ramifications as it encodes for antimicrobial resistance (AMR). This study aimed to identify multidrug-resistant (MDR) E. from cow's milk and evaluate their antimicrobial-resistant profiles. In total, 418 pooled samples were collected collection centers analysed using standard culture methods isolate coli. Antimicrobial Susceptibility Testing (AST) was...
African swine fever (ASF) is a contagious haemorrhagic disease associated with causing heavy economic losses to the industry in many countries. In 2017, Zambia experienced ASF outbreaks Mbala District (Northern province) and for first time Isoka Chinsali districts (Muchinga province). Meanwhile, another outbreak was observed Chipata (Eastern Genetic analysis of part B646L gene, E183L CP204L gene central variable region B602L virus (ASFV) conducted. The results revealed that ASFV detected...
Abstract Background Piroplasms are vector-borne intracellular hemoprotozoan parasites that infect wildlife and livestock. Wildlife species reservoir hosts to a diversity of piroplasms play an important role in the circulation, maintenance evolution these parasites. The potential for likely spillover both pathogenic non-pathogenic piroplasm from livestock is underlined when common ecological niche shared presence competent vector. Method To investigate cattle population greater Kafue...
Antimicrobial resistance (AMR) among
Mutations have driven the evolution and development of new variants severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with potential implications for increased transmissibility, disease severity vaccine escape among others. Genome sequencing is a technique that allows scientists to read genetic code an organism has become powerful tool studying emerging infectious diseases. Here, we conducted cross-sectional study in selected districts Eastern Province Zambia, from November 2021...
We detected West Nile virus (WNV) nucleic acid in crocodiles (Crocodylus niloticus) Zambia. Phylogenetically, the belonged to lineage 1a, which is predominant Northern Hemisphere. These data provide evidence that WNV circulating Africa and increases risk for animal human transmission.
The Kafue ecosystem is a vast conservation protected area comprising the National Park (KNP) and Game Management Areas (GMA) that act as buffer around national park. KNP has been neglected potential foci for rhodesiense sleeping sickness despite widespread presence of tsetse vector abundant wildlife reservoirs. aim this study was to generate information on circulating trypanosomes their eminent threat/risk public health livestock production steadily growing human population surrounding We...
African swine fever (ASF) causes persistent outbreaks in endemic and non-endemic regions Zambia. However, the epidemiology of disease is poorly understood, particularly during inter-epidemic periods. We conducted surveillance for ASF asymptomatic domestic pigs soft ticks selected Zambian provinces. While serum samples (n = 1,134) were collected from crossbred all study sites between 2014 2017, whole blood 300) was both indigenous Eastern Province (EP) 2017. Soft Mosi-oa-Tunya National Park...
Rift valley fever (RVF) is a mosquito-borne disease of animals and humans. Although RVF outbreaks are usually reported at 5-15-year intervals in sub-Saharan Africa, Zambia has experienced an unusually long inter-epizootic/-epidemic period more than three decades. However, serological evidence virus (RVFV) infection domestic ruminants during this underscores the need for comprehensive investigation mechanisms perpetuation emergence. Mosquitoes ( n = 16,778) captured from eight ten provinces...
Background An estimated 75% or more of the human rabies cases in Africa occur rural settings, which underscores importance control these areas. Understanding dog demographics can help design strategies for and plan conduct canine mass vaccination campaigns effectively African countries. Methodology/Principal findings A cross-sectional survey was conducted to investigate domestic Kalambabakali, Mazabuka District Zambia. The population ownerless dogs total achievable coverage among using...