A5061185006- Network Security and Intrusion Detection
- Plant biochemistry and biosynthesis
- Advanced Malware Detection Techniques
- Information and Cyber Security
- Complex Network Analysis Techniques
- Insect-Plant Interactions and Control
- Insect and Pesticide Research
- Opinion Dynamics and Social Influence
- Plant Gene Expression Analysis
- Tissue Engineering and Regenerative Medicine
- Biofuel production and bioconversion
- Advanced Decision-Making Techniques
- Internet Traffic Analysis and Secure E-voting
- Radiomics and Machine Learning in Medical Imaging
- Privacy-Preserving Technologies in Data
- Mesenchymal stem cell research
- Microbial Metabolic Engineering and Bioproduction
- Microbial infections and disease research
- Advanced Computational Techniques and Applications
- Fungal and yeast genetics research
- Biochemical and biochemical processes
- COVID-19 diagnosis using AI
- Cardiac Fibrosis and Remodeling
- Medical Imaging Techniques and Applications
- Enzyme Production and Characterization
Third Affiliated Hospital of Sun Yat-sen University
2010-2025
Sun Yat-sen University
2010-2025
Nanjing University of Chinese Medicine
2011-2025
Shanghai Jiao Tong University
2013-2024
Microbiology Institute of Shaanxi
2015-2024
Institute of Microbiology
2015-2024
Chinese Academy of Sciences
2010-2024
Wuhan University of Technology
2024
Hanseo University
2024
Zhongkai University of Agriculture and Engineering
2020-2022
Introduction Vancomycin-resistant Enterococcus faecalis (VRE) poses a significant challenge in clinical settings due to its resistance multiple antibiotics. Phage therapy offers promising alternative address this crisis. However, critical gaps remain regarding optimal dosing, therapeutic design, and treatment timing for phage targeting VRE-induced bacteremia. Methods The biological genomic characteristics of novel lytic specific VRE were investigated. Its vitro bactericidal antibiofilm...
Evaluating security threat status is very important in network management and analysis. A quantitative hierarchical evaluation model developed this paper to evaluate of a computer system the computational method based on structure importance services hosts. The policy from bottom top local global adopted model. indexes services, hosts networks are calculated by weighting attack frequency, severity bandwidth consumption, then evaluated. experiment results show that can provide intuitive three...
Pogostemon cablin (Blanco) Benth. (Patchouli) is an important aromatic and medicinal plant widely used in traditional Chinese medicine as well the perfume industry. Patchoulol primary bioactive component P. cablin, its biosynthesis has attracted widespread interests. Previous studies have surveyed putative genes involved patchoulol using next-generation sequencing method; however, technical limitations generated by short-read restrict yield of full-length genes. Additionally, little known...
ABSTRACT The increase in multidrug-resistant (MDR) Enterobacter cloacae complex (ECC) infections, particularly those resistant to carbapenems, underscores the urgent need for alternative therapies. Phage therapy, with its specific bactericidal action, offers a promising solution. However, there remains shortage of well-characterized ECC-targeting phages, and dosing timing optimization ECC-specific phage cocktails is largely unexplored. In this study, we isolated characterized three novel...
This study aimed to investigate the relationship between imaging features of pure ground-glass opacities (pGGOs) and pathological subtypes minimally invasive adenocarcinoma (MIA) precursor lesions. A retrospective analysis was conducted on data from 1521 patients diagnosed with GGOs as lung or lesions January 2015 March 2021. The pGGOs were categorized into atypical adenomatous hyperplasia (AAH) / in situ (AIS) MIA groups. Clinical information CT collected. Statistical analysis, logistic...
Changes of soil microbial communities are one the main factors continuous cropping problem. Andrographis paniculata has been reported to have replant problem in cultivation. However, little is known about variations rhizosphere A. under a system. Here, Illumina MiSeq was used investigate shifts rhizospheric bacterial and fungal after paniculata.The diversity increased whereas decreased consecutive monoculture; community structure differed between newly plant cropped soil. Taxonomic analyses...
Nicotinamide mononucleotide (NMN), a key precursor of NAD
Farnesyl pyrophosphate synthase (FPPS) plays an important role in the synthesis of plant secondary metabolites, but its function and molecular regulation mechanism remain unclear Pogostemon cablin . In this study, full-length cDNA FPP gene from P. ( PcFPPS ) was cloned characterized. The expressions are different among tissues (highly flowers). Subcellular localization analysis protoplasts indicated that located cytoplasm. functionally complemented lethal FPPS deletion mutation yeast CC25....
Target identification by modification-free proteomic approaches can potentially reveal the pharmacological mechanism of small molecular compounds. By combining recent solvent-induced protein precipitation (SIP) method with TMT-labeling quantitative proteomics, we propose proteome profiling (SIPP) approach to identify molecule-protein interactions. The SIPP enables depict denaturation curves target varying concentrations organic solvents induce unfolding and cellular proteome. using this...
Lysine succinylation is a novel, naturally occurring posttranslational modification (PTM) in living organisms. Global lysine identification has been performed at the proteomic level various species; however, study of plant species relatively limited. Patchouli (P. cablin (Blanco) Benth., Lamiaceae) globally important industrial and medicinal herb. In present study, succinylome analysis was carried out patchouli plants to determine potential regulatory role growth, development, physiology....
Open social network (OSN) plays a more significant role in information propagation through the rapid developing of technology. Since diffusion is an essential process happens OSN, it has been studied many studies. Several models have proposed to infer and reproduce network. However, these methods two critical problems: 1) ignoring effects user characteristics 2) inaccuracy resulted from calculating influence different features independently. To address limitations, inferring method based on...
Patchoulol, the major active ingredient in Pogostemon cablin (Blanco) Benth., has considerable clinical and industrial value. A number of genes that participate patchoulol biosynthesis pathway have been identified; however, little is known about transcription factors involved regulating synthesis. In this study, PatSWC4, a homologous protein Arabidopsis SWC4 belonging to MYB (v-myb avian myeloblastosis viral oncogene homolog)-related factor family, was identified characterized. Subcellular...
The production of patchoulol in the patchouli (Pogostemon cablin) plant determines its application value, as it is principal active sesquiterpene essential oil extracted from this plant. Here, promoter synthase gene (PatPTSpro) was isolated and found to be methyl jasmonate (MeJA)-induced. A nucleus-localized AP2/ERF transcription factor PatDREB identified a activator binding PatPTSpro, regulating biosynthesis through modulating expression. also interacts with ZIM-domain 4 (JAZ4)....