Obesity and abnormal lipid metabolism increase the risk of various cardiometabolic diseases, including diabetes, heart disease, stroke. However, impact abdominal obesity (AO) non-traditional parameters on multimorbidity (CMM) remains unclear. This study aims to investigate separate combined effects AO incidence CMM. enrolled 7,597 eligible participants from China health retirement longitudinal (CHARLS). Cox proportional hazards models were used perform adjusted regression analyses mediation...

Diagrams serve as a fundamental form of visual language, representing complex concepts and their inter-relationships through structured symbols, shapes, spatial arrangements. Unlike natural images, inherently symbolic abstract nature poses significant challenges for Multimodal Large Language Models (MLLMs). However, current benchmarks conflate perceptual reasoning tasks, making it difficult to assess whether MLLMs genuinely understand mathematical diagrams beyond superficial pattern...

Introduction Psychological distress in patients with pituitary adenomas affects their quality of life and is influenced by various aspects such as sociocultural factors, personal resources, stressors. Therefore, the aim this study was to investigate chain-mediated role self-efficacy rumination relationship between social support psychological distress. Methods The based on Wilson-Cleary model health-related theory. We investigated 500 surgically treated three tertiary hospitals Shaanxi...

Rice blast caused by Magnaporthe grisea is considered to be one of the most devastating diseases in rice-growing regions. In order search for an effective agent protect against rice infection, elicitor activity algino-oligosaccharides was evaluated germinating rice, which accumulation oryzalexin C could detected sensitively. The maximal seedlings when fractions alginate degradation products with a degree polymerization 7.9 (S3) and 6.5 (S4) were used as elicitors. Algino-oligosaccharides...

As a foodborne pathogen of global importance, Salmonella enterica serovar Enteritidis (S. Enteritidis) is threat to public health that mainly spread by poultry products. Intestinal Enterobacteriaceae can inhibit the colonization S. and are regarded as potential antibiotic substitute. We investigated, in chicks, anti-S. effects Escherichia coli (E. coli) Nissle 1917, most well-known probiotic member Enterobacteriaceae. Eighty 1-d-old healthy female AA broilers were randomly divided into 4...

Green mold of citrus, caused by Penicillium digitatum, is the most serious postharvest disease citrus. Sterol 14alpha-demethylase (CYP51) one key enzymes sterol biosynthesis in biological kingdoms and a prime target antifungal drugs. To exploit novel inhibitor (DMI) fungicides, DNA total RNA were isolated from P. digitatum. The CYP51 digitatum was cloned expressed Escherichia coli, yielding recombinant protein with molecular weight c. 59 kDa. (PdCYP51) purified polyclonal antibodies...

Hemoglobin (Hb)-based oxygen carriers (HBOCs) have been used as blood substitutes in surgery medicine and therapeutics for ischemic stroke. As a potent HBOC, the PEGylated Hb has received much attention its delivery plasma expanding ability. Two Hbs, Euro-Hb, MP4 developed clinical trials, using human adult hemoglobin (HbA) original substrate. However, HbA was obtained from outdated quantity available this source may not be sufficient mass production of HbA. In contrast, bovine (bHb) no...

Abstract Background Melatonin has attracted substantial attention because of its excellent prospects for both medical applications and crop improvement. The microbial production melatonin is a safer more promising alternative to chemical synthesis approaches. Researchers have failed produce high yields in common heterologous hosts due either the insolubility or low enzyme activity proteins encoded by gene clusters related biosynthesis. Results Here, combinatorial pathway was successfully...

This study developed an online solid-phase extraction ultra-high performance liquid chromatography-tandem mass spectrometry (Online-SPE-UHPLC-MS/MS) method for the analysis of 28 illegal drugs in sewage. To achieve this, isotope internal standards (ISTDs) were added to 3 mL sewage samples, pH was adjusted 7–8 using hydrochloric acid or 20% ammonia water, followed by centrifugation, filtration, and UHPLC-MS/MS. The results indicated excellent linearity 1–300 ng L−1, cotinine concentration...

Coronary heart disease (CHD) is the leading cause of mortality worldwide. Identifying effective diagnostic markers and understanding risk factors crucial for prevention management. This study aimed to investigate levels homocysteine (Hcy) lipoprotein-associated phospholipase A2 (Lp-PLA2) in human plasma their roles diagnosis prognosis CHD. A retrospective was conducted on 232 patients with CHD, divided into Acute Myocardial Infarction, unstable angina pectoris, stable pectoris groups, a...

To investigate the effects of Clostridium butyricum (C. butyricum) on breast muscle lipid metabolism broilers, 192 one-day-old male Arbor Acres broilers were randomly allocated into 2 treatments with 6 replicates in a completely randomised design. The fed corn-soybean meal-based diets and supplemented 0 or 1 × 109 cfu C. butyricum/kg diet for 42 days. birds butyricum-supplemented group showed higher (p < .05) average daily gain during grower phase throughout entire period experiment lower =...

Abstract Cells prevent heat damage through a highly conserved canonical stress response (HSR) in which shock factors (HSFs) bind elements (HSEs) to activate proteins (HSPs). Plants generate short HSFs that originate from HSF splicing variants, but little is known about S-HSFs. Although an enhanced HSR confers thermotolerance, its hyperactivation inhibits plant growth. How this process prevented ensure proper growth has not been determined. Here, we report Arabidopsis S-HsfA2, S-HsfA4c, and...

Cells prevent heat damage through a highly conserved canonical stress response (HSR) in which shock factors (HSFs) bind elements (HSEs) to activate proteins (HSPs). Plants generate short HSFs that originate from HSF splicing variants, but little is known about S-HSFs. Although an enhanced HSR confers thermotolerance, its hyperactivation inhibits plant growth. How this process prevented ensure proper growth has not been determined. Here, we report Arabidopsis S-HsfA2, S-HsfA4c, and S-HsfB1...

A high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (HPLC/Q-TOF MS) was developed for the analysis of chemical composition change in production process Re Du Ning injection, a Chinese medicine preparation combination Lonicera japonica Thunb., Gardenia jasminoides Ellis and Artemisia annua L. total 90 compounds from raw materials-intermediates-Re injection were detected; among them, 55 identified or tentatively characterized, characteristic ions...

This experiment was to study the effects of newly harvested corn on growth performance, intestine development and metabolism nutrients in broilers. A total 380 one-day-old Arbor Acres male broilers were assigned ageing group (AC group), 1/3 (1/3 NC 2/3 (2/3 (NC which according proportion amount basal diets. Each included six replicates with 16 birds. Digestion trials conducted at 39 42 days age. Results showed that feed: gain ratio (F/G) higher than 22 1 age (p < .05). The metabolic rates...