A5042318647- Bioactive natural compounds
- Power Systems and Renewable Energy
- Cancer, Stress, Anesthesia, and Immune Response
- Electric Power System Optimization
- Yersinia bacterium, plague, ectoparasites research
- Anesthesia and Neurotoxicity Research
- Lung Cancer Diagnosis and Treatment
- Extracellular vesicles in disease
- Radiomics and Machine Learning in Medical Imaging
- Child and Adolescent Psychosocial and Emotional Development
- Child Abuse and Trauma
- Nanoplatforms for cancer theranostics
- Plant Pathogens and Resistance
- Cardiac, Anesthesia and Surgical Outcomes
- Plant Gene Expression Analysis
- Plant Pathogens and Fungal Diseases
- Bacterial biofilms and quorum sensing
- Ovarian function and disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Plant Virus Research Studies
- Reproductive Biology and Fertility
- Nosocomial Infections in ICU
- Management of metastatic bone disease
- Antimicrobial agents and applications
- Cervical and Thoracic Myelopathy
Kunming Medical University
2019-2025
Peking University
2025
Peking University Cancer Hospital
2025
Donald Danforth Plant Science Center
2025
Zhejiang University of Technology
2024
Shanghai Electric (China)
2024
First People's Hospital of Foshan
2008-2023
Chinese Academy of Agricultural Sciences
2022-2023
Shandong Normal University
2023
Institute of Environment and Sustainable Development in Agriculture
2023
Resveratrol has been garnering considerable attention as a promising chemopreventive and chemotherapeutic drug against metastatic tumors such triple-negative breast cancer (TNBC). However, the potential in vivo application of resveratrol highly limited due to its poor solubility, rapid conjugation, low bioavailability, bioactivity. In this study, silica mesoporous nanoparticle (MSN)-based delivery system (DDS), named Au–Se@MSN, is developed deliver loaded resveratrol, endowing it with...
Abstract Forward genetic screens of mutant populations are fundamental for functional genomics studies. However, isolating independent alleles to molecularly identify causal genes is challenging in species recalcitrant manipulation. Here, we demonstrate that classic seed EMS mutagenesis coupled with genome sequencing can overcome this limitation sorghum. We used method generate new sorghum MALE STERILE 8 (MS8) and identified the locus ms8 phenotype as Sobic.004G270900, which encodes ortholog...
Maltreatment has negative effects on the parent-child relationship and emotional behavioral development of children. The current study aimed to examine associations among maltreatment, relationship, problems in Chinese children with or without oppositional defiant disorder (ODD). Participants included 259 ODD their 269 non-ODD counterparts from northern, eastern, southwestern China. We also collected data teachers fathers mothers. results showed that suffered more maltreatment had than...
The mechanisms by which plasminogen activator inhibitor-1 (PAI-1) regulates inflammation, especially in acute respiratory distress syndrome (ARDS), are largely unknown.To assess the relationship between PAI-1 and autophagy inflammatory reactions induced LPS rat NR8383 cells.ELISA was used to amounts of TNF-α, IL-1β, cell culture supernatants; TLR4, MyD88, PAI-1, LC3, Beclin1, mTOR protein mRNA levels were determined western blot quantitative RT-PCR, respectively; determine NF-κB levels. To...
Abstract The prickly nightshade Solanum rostratum , an annual malignant weed, is native to North America and has globally invaded 34 countries, causing serious threats ecosystems, agriculture, animal husbandry, human health. In this study, we constructed a chromosome-level genome assembly annotation of S. . contig-level was initially assembled in 898.42 Mb with contig N50 62.00 from PacBio high-fidelity reads. With Hi-C sequencing data scaffolding, 96.80% the sequences were anchored...
Recent studies have shown that propofol and sevoflurane, two common anesthetics, can prevent tumor development. The prevalence of lung adenocarcinoma in China is highest Yunnan Xuanwei, many patients with cancer this area are often resistant to platinum-based treatments.The objective the study was investigate effects sevoflurane on malignant biological behavior cisplatin resistance Xuanwei adenocarcinoma.Herein, XWLC-05/R, a cisplatin-resistant cell line XWLC-05 cells from adenocarcinoma,...
Growing evidence indicates that the tumor biomarker cytokeratin 19 fragment (CYFRA21-1) is significant for a variety of cancers. However, its role in epithelial ovarian cancer (EOC) has rarely been reported. In this study, receiver operating characteristic (ROC) curve was utilized to estimate diagnostic efficiency CYFRA21-1. The correlation between CYFRA21-1 level and prognosis analyzed by Kaplan-Meier survival analysis univariable multivariable analyses. relationship serum levels different...
Abstract Background Iris lactea var. chinensis , a perennial herbaceous species, is widely distributed and has good drought tolerance traits. However, there little information in public databases concerning this herb, so it difficult to understand the mechanism underlying its tolerance. Results In study, we used Illumina sequencing technology conduct an RNA (RNA-seq) analysis of I. plants under water-stressed conditions rehydration explore potential mechanisms involved plant The resulting de...
To explore the molecular mechanism of sevoflurane-induced neurotoxicity and to determine whether lncRNA HOXA11-AS affects neuronal apoptosis inflammation by regulating miR-98-5p/EphA4.Morris water maze (MWM) test was used detect learning memory ability rats, HE staining observe hippocampal pathology, TUNEL level apoptosis, RT-qPCR expression HOXA11-AS, miR-98-5p, IL-6, IL-1β, TNF-α. At same time, contents TNF-α in serum were detected ELISA. The expressions apoptosis-related proteins EphA4,...
Objectives. To estimate the incidence of chronic postthoracotomy pain (CPTP) in lung tumor patients and to explore influencing factors intensity CPTP. Methods. Lung who underwent video-assisted thoracoscopic surgery (VATS) or thoracotomy were consecutively recruited from October 2016 December 2017 at Yunnan Cancer Hospital. All eligible interviewed via telephone end third month after surgeries identify presence The potential CPTP, including pre-, intra-, postoperative variables, collected...
Concerns regarding the hepatotoxicity of adenovirus for cancer gene therapy have led to attempts engineer viruses tissue-specific expression and replication. The Tyrex2 (a tandem murine melanocyte-specific enhancer) system was used express luciferase, purine nucleoside phosphorylase (PNP), essential adenoviral E1A. In nonmelanoma cell lines, CMV promoter/enhancer (CMV p/e) 969 times stronger than construct, whereas in melanoma cells it only 2.6 stronger. An with regulating PNP (Ad2Tyr2-PNP)...
Abstract Patients receiving lipid emulsions are at increased risk of contracting catheter-related bloodstream infections (CRBSIs) in the clinic. More than 15% CRBSIs polymicrobial. The objective this study was to explore effects on formation Escherichia coli ( E. )– Candida albicans C. ) mixed-species biofilms (BFs) polyvinyl chloride (PVC) surfaces and underlying mechanism. Mixed-species BFs were produced by coculturing with PVC various concentrations emulsions. Crystal violet staining XTT...
Prostate cancer (PCa) is the second most frequently diagnosed and fifth leading cause of death from in men worldwide. Increased understanding prostate metastasis mechanisms will help identify more efficient intervention strategies to prevent or treat this deadly disease future. To candidate proteins that contribute PCa, isobaric tags for relative absolute quantitation (iTRAQ)-based proteomic analysis was performed explore differentially expressed between two homologous human cell lines...
The objective was to explore the relationships between computed tomography (CT) lung volume parameters and pulmonary function test (PFT) indexes develop predictive scores predict PFT in Chinese preoperative patients suspected with cancer. Preoperative cancer aged 18 years or more examined by chest CT scan PET were consecutively recruited from April August 2020, at Yunnan Cancer Hospital. data selected medical record. Pearson correlation used indexes. Predictive of developed unstandardized...
High dose of Zishen Yutai pill (ZYP) showed mild maternal toxicity in rat (24 g kg<sup>−1</sup> d<sup>−1</sup>, 96× clinical dose) and no reproductive rabbit (6 24× dose). ZYP could be safely used at the during pregnancy.