A5100459386- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Inflammatory mediators and NSAID effects
- Vascular Malformations and Hemangiomas
- Tumors and Oncological Cases
- Pancreatitis Pathology and Treatment
- Birth, Development, and Health
- Inflammasome and immune disorders
- Intestinal Malrotation and Obstruction Disorders
- Renal Diseases and Glomerulopathies
- Cardiac Fibrosis and Remodeling
- Abdominal Trauma and Injuries
- Lichen and fungal ecology
- Protease and Inhibitor Mechanisms
- Dermatological and COVID-19 studies
- Gastroesophageal reflux and treatments
- Gout, Hyperuricemia, Uric Acid
- Anorectal Disease Treatments and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Bone fractures and treatments
- Liver physiology and pathology
- Fibroblast Growth Factor Research
- Colorectal and Anal Carcinomas
- Chronic Kidney Disease and Diabetes
- Muscle and Compartmental Disorders
Fujian University of Traditional Chinese Medicine
2024
State Key Laboratory of Biotherapy
2017-2024
Sichuan University
2017-2024
Second Military Medical University
2024
Shanghai Pudong New Area Gongli Hospital
2024
Shanghai Children's Hospital
2022-2023
Shanghai Jiao Tong University
2022-2023
Fujian Medical University
2023
Union Hospital
2023
Mayo Clinic in Arizona
2021
Targeted gene delivery and enzyme inhibition in vascular perivascular cells promote engraftment of transplanted parenchymal for lung liver repair.
Islet transplantation is a promising therapy for Type 1 diabetes, but many attempts have failed due to early graft hypoxia or immune rejection, which generate reactive oxygen species (ROS). In the current study, we determined that transgenic overexpression of antioxidant metallothionein (MT) in pancreatic beta cells provided broad resistance oxidative stress by scavenging most kinds ROS including H2O2, peroxynitrite radical released from streptozotocin, 3-morpholinosydnonimine (SIN-1), and...
Dysfunction of the vascular angiocrine system is critically involved in regenerative defects and fibrosis injured organs. Previous studies have identified various factors found that risk such as aging metabolic disorders can disturb fibrotic One existing key gap what sense to modulate organ fibrosis. Here, using human mouse data, we discovered pathway hydrogen sulfide (H
Basic fibroblast growth factor (bFGF), a known angiogenic factor, may provide potential strategy for the treatment of myocardial infarction (MI), but it is limited by relatively short half-life. Dex-PCL-HEMA/PNIPAAm hydrogel provides reservoir controlled release factors. The aim current study was to evaluate effects bFGF incorporated into on angiogenesis and cardiac health in rat model acute MI, induced coronary artery ligation. Phosphate-buffered solution (PBS group), (Gel...
Abstract Background and purpose To investigate annular pancreas in adults using imaging features displayed on computed tomography (CT) magnetic resonance (MRI). Methods Retrospective review of patients undergoing CT or MRI examinations. Two abdominal radiologists blindly reviewed the CT, MRI, cholangiopancreatography (MRCP) images from Picture Archiving Communication Systems (PACS). A Kruskal–Wallis test was performed to evaluate subjective scoring, with Mann–Whitney for comparison. p ‐value...
Abstract Background It is challenging to identify residual or recurrent fistulas from the surgical region, while MR imaging feasible. The aim was use dynamic contrast-enhanced (DCE-MRI) technology distinguish between active anal fistula and postoperative healing (granulation) tissue. Methods Thirty-six patients following idiopathic underwent DCE-MRI. Subjects were divided into Group I (active fistula) IV (postoperative tissue), with latter II (≤ 75 days) III (> according 75-day interval...
Understanding the genomic diversity and functional implications of
Abstract Background To compare the efficacy of three-point locating versus routine techniques for implanting helical blades proximal femoral nail anti-rotation-II in treatment trochanteric fractures. Methods From January 2010 to June 2013, 90 patients with intertrochanteric fractures were surgically treated, including 48 males and 42 females an average age 70.5 ± 7.2 years. According AO classification, there 45 cases A2.1, 35 A2.2, 10 A2.3. Based on techniques, divided into two groups: group...
Background: Immune response mediated by T cells plays an important role in chronic hepatitis B (CHB). As immunoregulatory molecule, little is known about the characteristics of cell immunoglobulin and mucin-domain-containing molecule-3 (Tim-3) on cells. In this study, association Tim-3 its subset with clinical-virological features treatment-naïve CHB patients were identified. Methods: From July 2015 to January 2017, we carried-out a cross-sectional study which 320 different phases (immune...
<h3>Objectives</h3> Recentresearch porved the protective effects of synthesizced hydrogels (Gels) formyocardial infarction (MI) animals due to inhibition ventricularremodeling. However, cardiac malignant arrhythmia is one most seriouscomplications after MI, but exact mechanism underlying increased vulnerabilityof arrhythmias not clear. Synthesised hydrogel, as a kind non-bioactivematerial, whether hydrogel intra-myocardium injection could result in electrical reentry between non-bioactive...
Myocardial infarction and the subsequent heart failure remain among world’s prominent health challenges. Other studies have demonstrated that bio-derived materials improve cardiac function after implantation for angiogenic potential. In this study, we hypothesized injection of biomaterials into infarcted myocardium can preserve left ventricle (LV) through its prevention paradoxical systolic bulging. Infarction was induced in rabbit by coronary artery ligation. sham-operated rabbits (n = 5),...
组织微阵列/组织芯片技术是最近伴随基因芯片技术而发展的一种新方法,本研究对上海交通大学附属第一人民医院耳鼻喉-头颈外科85例喉癌患者的组织标本进行了研究,分析喉癌组织中环氧合酶(COX)-2、血管内皮生长因子(VEGF)和基质金属蛋白酶(MMP)-2等的表达,及探讨上述因素与流行病史,临床肿瘤、淋巴、转移分类(TNM分期)、病理分型、淋巴结转移、预后的关系,预测肿瘤的转归与预后,为手术及术后的综合治疗提供依据。