Qian Xu

ORCID: 0000-0001-5902-8305
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Research Areas
  • Acupuncture Treatment Research Studies
  • Cardiomyopathy and Myosin Studies
  • Pain Management and Placebo Effect
  • Autophagy in Disease and Therapy
  • Myofascial pain diagnosis and treatment
  • Healthcare and Venom Research
  • Pain Mechanisms and Treatments
  • Anesthesia and Pain Management
  • Traditional Chinese Medicine Studies
  • Cardiovascular Effects of Exercise
  • Viral Infections and Immunology Research
  • Botulinum Toxin and Related Neurological Disorders
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Growth Hormone and Insulin-like Growth Factors
  • Hypothalamic control of reproductive hormones
  • Obstructive Sleep Apnea Research
  • Diabetic Foot Ulcer Assessment and Management
  • Sirtuins and Resveratrol in Medicine
  • Studies on Chitinases and Chitosanases
  • Medical History and Innovations
  • Cannabis and Cannabinoid Research
  • Infant Health and Development
  • Foot and Ankle Surgery
  • Cellular Mechanics and Interactions
  • Sleep and related disorders

Nanjing University of Chinese Medicine
2019-2024

China Association of Acupuncture-Moxibustion
2024

Nanjing Second Hospital
2023

Fudan University
2020-2022

Jiangsu Province Hospital
2019-2022

Nanjing University
2019

University of California, Davis
2010

National Institutes of Health
2005

National Heart Lung and Blood Institute
2005

Dorsal root ganglia (DRG) plays an important role in mediating the peripheral sensation transduction through primary afferent neurons pain research. Neuropathic (NP) is a syndrome of hyperalgesia, spontaneous and allodynia caused by central or nerve injury. Recent trends study are turning towards development therapies for management NP. Activation autophagy glial cells spinal cord has been reported to be associated with attenuation NP, but autophagic process DRG rarely studied.The analgesic...

10.21037/atm-22-5920 article EN Annals of Translational Medicine 2022-12-01

Neuropathic pain (NP) is a syndrome that arises from central or peripheral nerve injury, which manifests primarily as hyperalgesia, spontaneous pain, and allodynia. The recent trend has exhibited shift towards the development of therapies for managing NP. Activation autophagy involved in function glial cells, may be implicated further to attenuate pain.In this study, analgesic effects electroacupuncture (EA) were evaluated among NP rats developed using spared injury (SNI). Acupuncture...

10.21037/atm-22-5273 article EN Annals of Translational Medicine 2022-12-01

Background The onset of puberty is influenced by thyroid function, and hormones (THs) fluctuate substantially during the period pubertal development. However, it needs to be further clarified how THs change at specific stages influences development in girls. So far, longitudinal data from China are scarce. Methods A cohort study was conducted among girls iodine-sufficient regions East between 2017 2019. Serum stimulating hormone (TSH), free triiodothyronine (FT3), thyroxine (FT4) were...

10.3389/fendo.2021.653680 article EN cc-by Frontiers in Endocrinology 2021-05-11

ObjectiveGrain-sized moxibustion is an effective treatment for hyperlipidemia, but how it regulates dyslipidemia and liver lipid deposits still needs to be fully understood. This study explored the molecular biological mechanism of grain-sized regulate hepatic autophagy in hyperlipidemic rats by affecting ULK1 TFEB through AMPK/mTOR signaling pathway.MethodsThirty male Sprague-Dawley (SD) were fed a high-fat diet eight weeks induce hyperlipidemia. Hyperlipidemic divided into HFD group, +...

10.1016/j.heliyon.2023.e15316 article EN cc-by-nc-nd Heliyon 2023-04-14

To observe the effect of acupuncture on expression transforming growth factor-β1(TGF-β1) in lacrimal gland rabbits with dry eye, so as to explore its underlying mechanism improving eye.Healthy male New Zealand were randomly assigned 5 groups (n=6 each group), namely, blank group, model western medicine group and sham group. The dye eye rabbit was estabilished by subcutaneous injection Scopolamine Hydrobromide solution for 21 days. After modeling, treated Flumirone drops their eyes 3 times a...

10.13702/j.1000-0607.190977 article EN PubMed 2020-09-25

Poor sleep quality and pain were common had been proved as an important influenced factor of life for patients with COPD. The association has observed in other population but remains unclear mild COPD from a community setting.A cross-sectional study was conducted to include eligible Pudong New District Shanghai. A structured questionnaire used collect general clinical information the patients. Chinese version Pittsburgh Sleep Quality Index (PSQI) short form McGill Pain Questionnaire (SF-MPQ)...

10.2147/jpr.s310036 article EN cc-by-nc Journal of Pain Research 2021-08-01

To explore the effect mechanism of moxibustion with wheat-grain size cone at "Zusanli" (ST 36) on vascular injury and oxidative stress in hyperlipidemia through mammalian target rapamycin (mTOR)/hypoxia inducible factor-1α (HIF-1α)/vascular endothelial growth factor (VEGF) signaling pathway.

10.13703/j.0255-2930.20230510-k0003 article EN PubMed 2024-04-12

To study the regularity of central response to thermal needle stimulation "Zusanli" (ST36) at different temperature, and analyze temperature difference responses.

10.13702/j.1000-0607.20221296 article EN PubMed 2024-04-25

The quantity of mild moxibustion stimulation is an important factor affecting clinical therapeutic effect. In the present study, we collected related literature by using key word "moxibustion quantity" from CNKI Database and make a summary about its concept. has two common characters, namely thermal intensity cumulative stimulating quantity, contains 6 components (parameters), including energy, stimulus, heated area skin, duration, frequency. According to facts mentioned above, hold that...

10.13702/j.1000-0607.180509 article EN PubMed 2019-07-25

To explore the antioxidant effect of moxibustion on vascular endothelial function and under-lying mechanism.Forty male SD rats were randomly divided into blank, model, nitric oxide synthase (eNOS) inhibitor groups, with 10 in each group. Hyperlipidemia rat model was established by high fat diet for 8 weeks. Rats group received 45 ℃ at "Zusanli" (ST36) min once daily consecutive 4 eNOS intraperitoneal injection L-NAME (1 mg/100 g) same time intervention. The morphology abdominal aorta...

10.13702/j.1000-0607.20220056 article EN PubMed 2023-04-25

The optimal management of intra-articular calcaneal fractures is still controversial. Open reduction and internal fixation are always associated with serious complications.Various alternative methods have been used variable effects. This retrospective study aimed to analyze the clinical efficacy safety a new "below-the-ankle" Ilizarov frame in patients caused by high-energy trauma.We retrospectively explored ten fractures, which four, five, one were Sanders type II, III, IV, respectively....

10.4103/njcp.njcp_1762_21 article EN Nigerian Journal of Clinical Practice 2022-07-01

Objective: BMI may play a protective role in reducing the mortality rate of patients with chronic obstructive pulmonary disease (COPD), but its effect on acute exacerbation COPD remain unclear. Methods: Subjects were selected from registration system established 2014 Pudong new district, Shanghai. 8 communities by cluster sampling and follow up was conducted prospectively for 18 months. Basic information obtained baseline survey, exacerbations collected during follow-up. The association...

10.3760/cma.j.cn112338-20211130-00938 article EN PubMed 2022-09-10

According to indications of Sanguan (cun, guan and chi, three places at the wrist where pulse is usually taken) described in book Mai Jing (Pulse Classic), selection acupoints based on location problems conditions. WANG Shu-he (201-280, a well-known physician Wei Jin dynasties) chose operation method stimulating intensity according nature clinical disorders, that is, performing acupuncture or moxibusion accordance with conditions, reinforcing reducing needling manipulations Clinical...

10.13702/j.1000-0607.190109 article EN PubMed 2019-08-25

Objective: To explore the effects of different puberty development stages on thyroid morphology and function in women. Methods: From October to November 2017, a multi-stage cluster sampling method was used select one junior high school Minhang district Shanghai, Haimen city Jiangsu province, Yuhuan Zhejiang province Deqing county respectively. A total 491 girls first grade 4 schools were included study. The subjects examined with B-ultrasound physical examination, their morning random urine...

10.3760/cma.j.cn112338-20190626-00470 article EN PubMed 2020-06-10

A literature review was performed to investigate the possible mechanism of scalp acupuncture in stimulating skin, fascia, muscle, and periosteum thus affecting cerebral cortex function. The results research show that effect on function may be achieved by stimulation specific anatomical structures. Stimulation muscle can activate functional areas through midbrain, thalamus, brainstem. In addition, different depths affect deep shallow sensation brain, self-monitoring subcortical central...

10.13702/j.1000-0607.190627 article EN PubMed 2020-06-25

To investigate the effects of mild moxibustion at 45°C on chronic inflammatory response abdominal aorta in rats with hyperlipidemia and different durations.Thirty-six SD were randomly divided into following groups: blank control group (2 weeks), model (4 weeks). A inflammation was established through high-fat diet feeding for 8 weeks. Rats groups received treatment bilateral "Zusanli"(ST36) 45 °C, 10 min every time, once a day, consecutive 2 or 4 The morphology each observed by using HE...

10.13702/j.1000-0607.20221039 article EN PubMed 2023-09-25
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